Search Results - "Felts, Richard"
-
1
3D visualization of HIV transfer at the virological synapse between dendritic cells and T cells
Published in Proceedings of the National Academy of Sciences - PNAS (27-07-2010)“…The efficiency of HIV infection is greatly enhanced when the virus is delivered at conjugates between CD4⁺ T cells and virus-bearing antigen-presenting cells…”
Get full text
Journal Article -
2
HIV-1 activates Cdc42 and induces membrane extensions in immature dendritic cells to facilitate cell-to-cell virus propagation
Published in Blood (03-11-2011)“…HIV-1 cell-to-cell transmission confers a strong advantage as it increases efficiency of transfer up to 100-fold compared with a cell-free route. Mechanisms of…”
Get full text
Journal Article -
3
Structure of Francisella tularensis AcpA: PROTOTYPE OF A UNIQUE SUPERFAMILY OF ACID PHOSPHATASES AND PHOSPHOLIPASES C
Published in The Journal of biological chemistry (06-10-2006)“…AcpA is a respiratory burst-inhibiting acid phosphatase from the Centers for Disease Control and Prevention Category A bioterrorism agent Francisella…”
Get full text
Journal Article -
4
Crystal Structures of the Histidine Acid Phosphatase from Francisella tularensis Provide Insight into Substrate Recognition
Published in Journal of molecular biology (18-12-2009)“…Histidine acid phosphatases catalyze the transfer of a phosphoryl group from phosphomonoesters to water at acidic pH using an active-site histidine. The…”
Get full text
Journal Article -
5
Characterization of a Unique Class C Acid Phosphatase from Clostridium perfringens
Published in Applied and Environmental Microbiology (01-06-2009)“…Clostridium perfringens is a gram-positive anaerobe and a pathogen of medical importance. The detection of acid phosphatase activity is a powerful diagnostic…”
Get full text
Journal Article -
6
Structure of Recombinant Haemophilus Influenzae e (P4) Acid Phosphatase Reveals a New Member of the Haloacid Dehalogenase Superfamily
Published in Biochemistry (Easton) (02-10-2007)“…Lipoprotein e (P4) from Haemophilus influenzae belongs to the “DDDD” superfamily of phosphohydrolases and is the prototype of class C nonspecific acid…”
Get full text
Journal Article -
7
Characterization of recombinant Francisella tularensis acid phosphatase A
Published in Protein expression and purification (2006)“…Francisella tularensis is the etiologic agent of the potentially fatal human disease tularemia and is capable of survival and multiplication within…”
Get full text
Journal Article -
8
Crystallization of AcpA, a respiratory burst-inhibiting acid phosphatase from Francisella tularensis
Published in Biochimica et biophysica acta (31-08-2005)“…Francisella tularensis is a highly infectious bacterial pathogen that is classified as a Category A Pathogen by the Centers for Disease Control and Prevention…”
Get full text
Journal Article -
9
Structure of Francisella tularensis AcpA
Published in The Journal of biological chemistry (06-10-2006)“…AcpA is a respiratory burst-inhibiting acid phosphatase from the Centers for Disease Control and Prevention Category A bioterrorism agent Francisella…”
Get full text
Journal Article -
10
Expression, purification and crystallization of class C acid phosphatases from Francisella tularensis and Pasteurella multocida
Published in Acta crystallographica. Section F, Structural biology and crystallization communications (01-03-2009)“…Class C nonspecific acid phosphatases are bacterial enzymes that are secreted across the cytoplasmic membrane and hydrolyze a variety of phosphomonoesters at…”
Get full text
Journal Article -
11
Cloning, purification and crystallization of Bacillus anthracis class C acid phosphatase
Published in Acta crystallographica. Section F, Structural biology and crystallization communications (01-07-2006)“…Cloning, expression, purification and crystallization studies of a recombinant class C acid phosphatase from the Category A pathogen Bacillus anthracis are…”
Get full text
Journal Article -
12
Crystallization of recombinant Haemophilus influenzae e (P4) acid phosphatase
Published in Acta crystallographica. Section F, Structural biology and crystallization communications (01-05-2006)“…Haemophilus influenzae infects the upper respiratory tract of humans and can cause infections of the middle ear, sinuses and bronchi. The virulence of the…”
Get full text
Journal Article -
13
Crystallization of a newly discovered histidine acid phosphatase from Francisella tularensis
Published in Acta crystallographica. Section F, Structural biology and crystallization communications (01-01-2006)“…Francisella tularensis is a highly infectious bacterial pathogen that is considered by the Centers for Disease Control and Prevention to be a potential…”
Get full text
Journal Article -
14
HTV-1 activates Cdc42 and induces membrane extensions in immature dendritic cells to facilitate cell-to-cell virus propagation
Published in Blood (2011)Get full text
Journal Article -
15
Crystallization of recombinant Haemophilus influenzaee (P4) acid phosphatase
Published in Acta crystallographica. Section F, Structural biology and crystallization communications (01-05-2006)“…Haemophilus influenzae infects the upper respiratory tract of humans and can cause infections of the middle ear, sinuses and bronchi. The virulence of the…”
Get full text
Journal Article -
16
Structural studies of acid phosphatases from pathogenic bacteria
Published 01-01-2007“…Acid phosphatases are important, ubiquitous, and diverse group of enzymes that catalyze the transfer of phosphoryl from phosphomonoester to water forming…”
Get full text
Dissertation