Search Results - "Felter, S"

Diapered skin and diaper dermatitis: Implications for risk assessment by Felter, S.

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Maximizing use of existing carcinogenicity data to support acceptable intake levels for mutagenic impurities in pharmaceuticals: Learnings from N-nitrosamine case studies by Felter, S.P., Ponting, D.J., Mudd, A.M., Thomas, R., Oliveira, A.A.F.

“…The unexpected finding of N-nitrosamine (NA) impurities in many pharmaceutical products raised significant challenges for industry and regulators. In addition…”
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A safety assessment of coumarin taking into account species-specificity of toxicokinetics by Felter, S.P., Vassallo, J.D., Carlton, B.D., Daston, G.P.

“…Coumarin (1,2-benzopyrone) is a naturally occurring fragrant compound found in a variety of plants and spices. Exposure to the general public is through the…”
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Skin hydration analysis by experiment and computer simulations and its implications for diapered skin by Saadatmand, M, Stone, K J, Vega, V N, Felter, S, Ventura, S, Kasting, G, Jaworska, J

“…Experimental work on skin hydration is technologically challenging, and mostly limited to observations where environmental conditions are constant. In some…”
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Evolution of Science-Based Uncertainty Factors in Noncancer Risk Assessment by Dourson, Michael L., Felter, Susan P., Robinson, Denise

“…The science behind the use of uncertainty factors has progressed considerably. Increased knowledge of inter- and intraspecies sensitivity, mechanisms of…”
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An exposure-based risk assessment approach to confirm the safety of hydrogen peroxide for use in home tooth bleaching by Mahony, C., Felter, S.P., McMillan, D.A.

“…Hydrogen peroxide has a long history of safe use in a wide variety of medical and consumer products, including oral care products. The use of hydrogen peroxide…”
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Introduction into the tiered TTC concept by Kosemund, K., Felter, S.

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Application of the threshold of toxicological concern approach to ingredients in personal and household care products by Blackburn, Karen, Stickney, Julie A., Carlson-Lynch, Heather L., McGinnis, Patricia M., Chappell, Lara, Felter, Susan P.

“…In the absence of chemical-specific data, the threshold of toxicological concern (TTC) provides a method to determine a conservative estimate of a chronic oral…”
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Understanding fragrance allergy using an exposure‐based risk assessment approach by Gerberick, G. Frank, Robinson, Michael K, Felter, Susan P, White, Ian R, Basketter, David A

“…Conducting a sound skin sensitization risk assessment prior to the introduction of new ingredients and products into the market place is essential. The process…”
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A review of the scientific basis for uncertainty factors for use in quantitative risk assessment for the induction of allergic contact dermatitis by Felter, Susan P., Robinson, Michael K., Basketter, David A., Gerberick, G. Frank

“…Safety evaluations for chemicals which possess the ability to cause sensitization by skin contact have traditionally been done using an ad hoc comparative risk…”
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A relative navigation system for formation flight by Felter, S.C., Wu, N.E.

“…A relative navigation system based on both the Inertial Navigation System (INS) and the Global Positioning System (GPS) is developed to support situational…”
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Application of the risk assessment paradigm to the induction of allergic contact dermatitis by Felter, Susan P, Ryan, Cindy A, Basketter, David A, Gilmour, Nicola J, Gerberick, G.Frank

“…The National Academy of Science (NAS) risk assessment paradigm has been widely accepted as a framework for estimating risk from exposure to environmental…”
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Hexavalent Chromium-Contaminated Soils: Options for Risk Assessment and Risk Management by Felter, Susan P, Dourson, Michael L

“…Risk assessment involves establishing scientifically defensible dose–response relationships for end points of concern. For Cr(VI)-contaminated soils, this…”
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Acrylonitrile: A Reevaluation of the Database to Support an Inhalation Cancer Risk Assessment by Felter, Susan P., Dollarhide, Joan S.

“…Acrylonitrile (ACN) is a monomer used extensively in the production of plastics, synthetic fibers, and rubber. In previous assessments conducted by IARC and…”
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Route-to-Route Extrapolation of the Toxic Potency of MTBE by Dourson, Michael L., Felter, Susan P.

“…MTBE is a volatile organic compound used as an oxygenating agent in gasoline. Inhalation from fumes while refueling automobiles is the principle route of…”
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Refining the threshold of toxicological concern (TTC) for risk prioritization of trace chemicals in food by Felter, Susan, Lane, Richard W., Latulippe, Marie E., Craig Llewellyn, G., Olin, Stephen S., Scimeca, Joseph A., Trautman, Thomas D.

“…Due to ever-improving analytical capabilities, very low levels of unexpected chemicals can now be detected in foods. Although these may be toxicologically…”
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Gastrointestinal Absorption of Metals by Diamond, Gary L., Goodrum, Philip E., Felter, Susan P., Ruoff, William L.

“…ABSTRACT Estimating gastrointestinal absorption remains a significant challenge in the risk assessment of metals. This presentation reviews our current…”
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Distribution of Exposure Concentrations and Doses for Constituents of Environmental Tobacco Smoke by LaKind, J S, Ginevan, ME, Naiman, D Q, James, A C, Jenkins, R A, Dourson, M L, Felter, S P, Graves, C G, Tardiff, R G

“…The ultimate goal of the research reported in this series of three articles is to derive distributions of doses of selected environmental tobacco smoke…”
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Gastrointestinal Absorption of Metals by Diamond, Gary L., Goodrum, Philip E., Felter, Susan P., Ruoff, William L.

“…ABSTRACT Estimating gastrointestinal absorption remains a significant challenge in the risk assessment of metals. This presentation reviews our current…”
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Yeast mitochondrial and cytoplasmic valyl-tRNA synthetases by Felter, S, Diatewa, M, Schneider, C, Stahl, A J

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