Search Results - "Felsenstein, Matthäus"

IPMNs with co-occurring invasive cancers: neighbours but not always relatives by Felsenstein, Matthäus, Noë, Michaël, Masica, David L, Hosoda, Waki, Chianchiano, Peter, Fischer, Catherine G, Lionheart, Gemma, Brosens, Lodewijk A A, Pea, Antonio, Yu, Jun, Gemenetzis, Georgios, Groot, Vincent P, Makary, Martin A, He, Jin, Weiss, Matthew J, Cameron, John L, Wolfgang, Christopher L, Hruban, Ralph H, Roberts, Nicholas J, Karchin, Rachel, Goggins, Michael G, Wood, Laura D

“…Intraductal papillary mucinous neoplasms (IPMNs) are precursor lesions that can give rise to invasive pancreatic carcinoma. Although approximately 8% of…”
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Challenges of single-stage pancreatoduodenectomy: how to address pancreatogastrostomies with robotic-assisted surgery by Timmermann, Lea, Hillebrandt, Karl Herbert, Felsenstein, Matthäus, Schmelzle, Moritz, Pratschke, Johann, Malinka, Thomas

“…Introduction Establishing a sufficient pancreatico-enteric anastomosis remains one of the most important challenges in open single stage pancreatoduodenectomy…”
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Recurrent Rearrangements in PRKACA and PRKACB in Intraductal Oncocytic Papillary Neoplasms of the Pancreas and Bile Duct by Singhi, Aatur D., Wood, Laura D., Parks, Emma, Torbenson, Michael S., Felsenstein, Matthäus, Hruban, Ralph H., Nikiforova, Marina N., Wald, Abigail I., Kaya, Cihan, Nikiforov, Yuri E., Favazza, Laura, He, Jin, McGrath, Kevin, Fasanella, Kenneth E., Brand, Randall E., Lennon, Anne Marie, Furlan, Alessandro, Dasyam, Anil K., Zureikat, Amer H., Zeh, Herbert J., Lee, Kenneth, Bartlett, David L., Slivka, Adam

“…Intraductal oncocytic papillary neoplasms (IOPNs) of the pancreas and bile duct contain epithelial cells with numerous, large mitochondria and are cystic…”
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Prevalence of Germline Mutations Associated With Cancer Risk in Patients With Intraductal Papillary Mucinous Neoplasms by Skaro, Michael, Nanda, Neha, Gauthier, Christian, Felsenstein, Matthäus, Jiang, Zhengdong, Qiu, Miaozhen, Shindo, Koji, Yu, Jun, Hutchings, Danielle, Javed, Ammar A., Beckman, Ross, He, Jin, Wolfgang, Christopher L., Thompson, Elizabeth, Hruban, Ralph H., Klein, Alison P., Goggins, Michael, Wood, Laura D., Roberts, Nicholas J.

“…Many patients with pancreatic adenocarcinoma carry germline mutations associated with increased risk of cancer. It is not clear whether patients with…”
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Internal drainage for interdisciplinary management of anastomotic leakage after pancreaticogastrostomy by Felsenstein, Matthäus, Amini, Ann-Christin, Dorfer, Sophie, Hu, Mengwen, Wang, Ruonan, Timmermann, Lea, Hillebrandt, Karl Herbert, Benzing, Christian, Fehrenbach, Uli, Pelzer, Uwe, Sauer, Igor Maximillian, Pratschke, Johann, Jürgensen, Christian, Malinka, Thomas

“…Background Anastomotic leakage and postoperative pancreatic fistula (POPF) may occur after pancreatic head resection, also in the setting of pancreato-gastric…”
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New Developments in the Molecular Mechanisms of Pancreatic Tumorigenesis by Felsenstein, Matthäus, Hruban, Ralph H, Wood, Laura D

“…Pancreatic cancer is an aggressive disease with a dismal prognosis in dire need of novel diagnostic and therapeutic approaches. The past decade has witnessed…”
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Robotic versus open pancreatic surgery: a propensity score-matched cost-effectiveness analysis by Benzing, Christian, Timmermann, Lea, Winklmann, Thomas, Haiden, Lena Marie, Hillebrandt, Karl Herbert, Winter, Axel, Maurer, Max Magnus, Felsenstein, Matthäus, Krenzien, Felix, Schmelzle, Moritz, Pratschke, Johann, Malinka, Thomas

“…Background Robotic pancreatic surgery (RPS) is associated with high intraoperative costs compared to open pancreatic surgery (OPS). However, it remains unclear…”
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Molecular characterization of organoids derived from pancreatic intraductal papillary mucinous neoplasms by Huang, Bo, Trujillo, Maria A, Fujikura, Kohei, Qiu, Miaozhen, Chen, Fei, Felsenstein, Matthäus, Zhou, Cancan, Skaro, Michael, Gauthier, Christian, Macgregor‐Das, Anne, Hutchings, Danielle, Hong, Seung‐Mo, Hruban, Ralph H, Eshleman, James R, Thompson, Elizabeth D, Klein, Alison P, Goggins, Michael, Wood, Laura D, Roberts, Nicholas J

“…Intraductal papillary mucinous neoplasms (IPMNs) are commonly identified non‐invasive cyst‐forming pancreatic neoplasms with the potential to progress into…”
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Robotic-assisted pancreatic surgery in the elderly patient: experiences from a high-volume centre by Hillebrandt, Karl H, Knitter, Sebastian, Timmermann, Lea, Felsenstein, Matthäus, Benzing, Christian, Schmelzle, Moritz, Pratschke, Johann, Malinka, Thomas

“…Robotic-assisted pancreatic surgery (RPS) has fundamentally developed over the past few years. For subgroups, e.g. elderly patients, applicability and safety…”
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PBRM1 loss is a late event during the development of cholangiocarcinoma by Luchini, Claudio, Robertson, Scott A, Hong, Seung‐Mo, Felsenstein, Matthäus, Anders, Robert A, Pea, Antonio, Nottegar, Alessia, Veronese, Nicola, He, Jin, Weiss, Matthew J, Capelli, Paola, Scarpa, Aldo, Argani, Pedram, Kapur, Payal, Wood, Laura D

“…Aims Somatic mutations in genes encoding chromatin remodellers have been reported recently in several cancer types, including approximately half of…”
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Perineural Invasion in Pancreatic Ductal Adenocarcinoma (PDAC): A Saboteur of Curative Intended Therapies? by Felsenstein, Matthäus, Lindhammer, Flora, Feist, Mathilde, Hillebrandt, Karl Herbert, Timmermann, Lea, Benzing, Christian, Globke, Brigitta, Zocholl, Dario, Hu, Mengwen, Fehrenbach, Uli, Sinn, Bruno Valentin, Pelzer, Uwe, Sauer, Igor Maximillian, Pratschke, Johann, Malinka, Thomas

“…(1) Background: Perineural invasion (PNI) is a common characteristic of pancreatic ductal adenocarcinoma (PDAC) and is present in most resection margins. We…”
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Clinical prognosticators and targets in the immune microenvironment of intrahepatic cholangiocarcinoma by Lozzi, Isis, Arnold, Alexander, Barone, Matthias, Johnson, Juliette Claire, Sinn, Bruno V, Eschrich, Johannes, Gebert, Pimrapat, Wang, Ruonan, Hu, Mengwen, Feldbrügge, Linda, Schirmeier, Anja, Reutzel-Selke, Anja, Malinka, Thomas, Krenzien, Felix, Schöning, Wenzel, Modest, Dominik P, Pratschke, Johann, Sauer, Igor M, Felsenstein, Matthäus

“…Intrahepatic cholangiocarcinoma (ICC) is a disease with poor prognosis and limited therapeutic options. We investigated the tumor immune microenvironment…”
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Whole-exome sequencing of duodenal neuroendocrine tumors in patients with neurofibromatosis type 1 by Noë, Michaël, Pea, Antonio, Luchini, Claudio, Felsenstein, Matthäus, Barbi, Stefano, Bhaijee, Feriyl, Yonescu, Raluca, Ning, Yi, Adsay, N. Volkan, Zamboni, Giuseppe, Lawlor, Rita T., Scarpa, Aldo, Offerhaus, G. Johan A., Brosens, Lodewijk A.A., Hruban, Ralph H., Roberts, Nicholas J., Wood, Laura D.

“…Neurofibromatosis type 1 (NF1) is a hereditary cancer predisposition syndrome characterized by frequent cutaneous and nervous system abnormalities. Patients…”
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Generation and characterization of a cell line from an intraductal tubulopapillary neoplasm of the pancreas by Felsenstein, Matthäus, Trujillo, Maria A., Huang, Bo, Nanda, Neha, Jiang, Zhengdong, Jeong, Yea Ji, Pflüger, Michael, Goggins, Michael G., Hruban, Ralph H., Thompson, Elizabeth D., Heaphy, Christopher M., Roberts, Nicholas J., Wood, Laura D.

“…Intraductal tubulopapillary neoplasm (ITPN) is a distinct precancerous lesion in the pancreas with unique clinical and molecular features. Although in vitro…”
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Feasibility of robotic-assisted pancreatic resection in patients with previous minor abdominal surgeries: a single-center experience of the first three years by Ritschl, Paul Viktor, Miller, Hannah Kristin, Hillebrandt, Karl, Timmermann, Lea, Felsenstein, Matthäus, Benzing, Christian, Globke, Brigitta, Öllinger, Robert, Schöning, Wenzel, Schmelzle, Moritz, Pratschke, Johann, Malinka, Thomas

“…Robotic-assisted pancreatic surgery is limited to specialized high-volume centers and selected patient cohorts. Especially for patients with a history of…”
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Sensing Acute Cellular Rejection in Liver Transplant Patients Using Liver-Derived Extracellular Particles: A Prospective, Observational Study by Kamali, Kaan, Schmelzle, Moritz, Kamali, Can, Brunnbauer, Philipp, Splith, Katrin, Leder, Annekatrin, Berndt, Nadja, Hillebrandt, Karl-Herbert, Raschzok, Nathanael, Feldbrügge, Linda, Felsenstein, Matthäus, Gaßner, Joseph, Ritschl, Paul, Lurje, Georg, Schöning, Wenzel, Benzing, Christian, Pratschke, Johann, Krenzien, Felix

“…Acute cellular rejection (ACR) after liver transplantation (LT) goes along with allograft dysfunction, which is diagnosed by liver biopsy and concomitant…”
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Extracellular NAD+ response to post-hepatectomy liver failure: bridging preclinical and clinical findings by Kamali, Can, Brunnbauer, Philipp, Kamali, Kaan, Saqr, Al-Hussein Ahmed, Arnold, Alexander, Harman Kamali, Gulcin, Babigian, Julia, Keshi, Eriselda, Mohr, Raphael, Felsenstein, Matthäus, Moosburner, Simon, Hillebrandt, Karl-Herbert, Bartels, Jasmin, Sauer, Igor Maximilian, Tacke, Frank, Schmelzle, Moritz, Pratschke, Johann, Krenzien, Felix

“…Liver fibrosis progressing to cirrhosis is a major risk factor for liver cancer, impacting surgical treatment and survival. Our study focuses on the role of…”
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Gastric cancer following pancreaticoduodenectomy: Experience from a high-volume center and review of existing literature by Pflüger, Michael Johannes, Felsenstein, Matthäus, Schmocker, Ryan, Wood, Laura DeLong, Hruban, Ralph, Fujikura, Kohei, Rozich, Noah, van Oosten, Floortje, Weiss, Matthew, Burns, William, Yu, Jun, Cameron, John, Pratschke, Johann, Wolfgang, Christopher Lee, He, Jin, Burkhart, Richard Andrew

“…Prolonged survival of patients after pancreaticoduodenectomy can be associated with late complications due to altered gastrointestinal anatomy. The incidence…”
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Multiregion whole-exome sequencing of intraductal papillary mucinous neoplasms reveals frequent somatic KLF4 mutations predominantly in low-grade regions by Fujikura, Kohei, Hosoda, Waki, Felsenstein, Matthäus, Song, Qianqian, Reiter, Johannes G, Zheng, Lily, Beleva Guthrie, Violeta, Rincon, Natalia, Dal Molin, Marco, Dudley, Jonathan, Cohen, Joshua D, Wang, Pei, Fischer, Catherine G, Braxton, Alicia M, Noë, Michaël, Jongepier, Martine, Fernández-Del Castillo, Carlos, Mino-Kenudson, Mari, Schmidt, C Max, Yip-Schneider, Michele T, Lawlor, Rita T, Salvia, Roberto, Roberts, Nicholas J, Thompson, Elizabeth D, Karchin, Rachel, Lennon, Anne Marie, Jiao, Yuchen, Wood, Laura D

“…Intraductal papillary mucinous neoplasms (IPMNs) are non-invasive precursor lesions that can progress to invasive pancreatic cancer and are classified as…”
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VEGF as a modulator of the innate immune response in glioblastoma by Turkowski, Kati, Brandenburg, Susan, Mueller, Annett, Kremenetskaia, Irina, Bungert, Alexander D., Blank, Anne, Felsenstein, Matthäus, Vajkoczy, Peter

“…VEGF is an important factor in tumor vascularization and used as target for anti‐angiogenic treatment strategies in glioma. In this study, we demonstrate for…”
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