Search Results - "Felmlee, J."
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Mechanisms of Hepatitis C Viral Resistance to Direct Acting Antivirals
Published in Viruses (18-12-2015)“…There has been a remarkable transformation in the treatment of chronic hepatitis C in recent years with the development of direct acting antiviral agents…”
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A targeted functional RNA interference screen uncovers glypican 5 as an entry factor for hepatitis B and D viruses
Published in Hepatology (Baltimore, Md.) (01-01-2016)“…Chronic hepatitis B and D infections are major causes of liver disease and hepatocellular carcinoma worldwide. Efficient therapeutic approaches for cure are…”
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Syndecan 4 is involved in mediating HCV entry through interaction with lipoviral particle-associated apolipoprotein E
Published in PloS one (01-04-2014)“…Hepatitis C virus (HCV) is a major cause of liver disease worldwide and HCV infection represents a major health problem. HCV associates with host lipoproteins…”
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Infection with the hepatitis C virus causes viral genotype-specific differences in cholesterol metabolism and hepatic steatosis
Published in Scientific reports (01-04-2022)“…Lipids play essential roles in the hepatitis C virus (HCV) life cycle and patients with chronic HCV infection display disordered lipid metabolism which…”
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Reconstitution of the Entire Hepatitis C Virus Life Cycle in Nonhepatic Cells
Published in Journal of Virology (01-11-2012)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Cartilage T1ρ and T2 relaxation times: longitudinal reproducibility and variations using different coils, MR systems and sites
Published in Osteoarthritis and cartilage (01-12-2015)“…Summary Objective To evaluate the longitudinal reproducibility and variations of cartilage T1ρ and T2 measurements using different coils, MR systems and sites…”
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MRI as a biomarker of disease progression in a therapeutic trial of milameline for AD
Published in Neurology (28-01-2003)“…To assess the feasibility of using MRI measurements as a surrogate endpoint for disease progression in a therapeutic trial for AD. A total of 362 patients with…”
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Hepatitis C virus, cholesterol and lipoproteins--impact for the viral life cycle and pathogenesis of liver disease
Published in Viruses (23-05-2013)“…Hepatitis C virus (HCV) is a leading cause of chronic liver disease, including chronic hepatitis, fibrosis, cirrhosis, and hepatocellular carcinoma. Hepatitis…”
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Journal Article Book Review -
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New perspectives for preventing hepatitis C virus liver graft infection
Published in The Lancet infectious diseases (01-06-2016)“…Summary Hepatitis C virus (HCV) infection is a leading cause of end-stage liver disease that necessitates liver transplantation. The incidence of virus-induced…”
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Magnetic resonance elastography: Non-invasive mapping of tissue elasticity
Published in Medical image analysis (01-12-2001)“…Magnetic resonance elastography (MRE) is a phase-contrast-based MRI imaging technique that can directly visualize and quantitatively measure propagating…”
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HCV and the hepatic lipid pathway as a potential treatment target
Published in Journal of hepatology (01-12-2011)“…Atherosclerosis has been described as a liver disease of the heart [1] . The liver is the central regulatory organ of lipid pathways but since dyslipidaemias…”
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PCSK9, apolipoprotein E and lipoviral particles in chronic hepatitis C genotype 3: Evidence for genotype-specific regulation of lipoprotein metabolism
Published in Journal of hepatology (01-04-2015)“…Background & Aims Hepatitis C virus (HCV) associates with lipoproteins to form “lipoviral particles” (LVPs) that can facilitate viral entry into hepatocytes…”
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Intravascular Transfer Contributes to Postprandial Increase in Numbers of Very-Low-Density Hepatitis C Virus Particles
Published in Gastroenterology (New York, N.Y. 1943) (01-11-2010)“…Background & Aims The physical association of hepatitis C virus (HCV) particles with lipoproteins in plasma results in distribution of HCV in a broad range of…”
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Entry of hepatitis B and C viruses — recent progress and future impact
Published in Current opinion in virology (01-02-2014)“…•HCV entry is a multifactorial highly regulated process; understanding of HBV entry is in its infancy.•The importance of establishing differentiated polarized…”
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Interferon‐lambda polymorphisms and hepatitis C virus clearance revisited
Published in Hepatology (Baltimore, Md.) (01-07-2013)“…Abstract Chronic infection with hepatitis C virus (HCV) is a common cause of liver cirrhosis and cancer. We performed RNA sequencing in primary human…”
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Practical implementation of robust MR-thermometry during clinical MR-guided microwave ablations in the liver at 1.5 T
Published in Physica medica (01-11-2019)“…•Practical measures to achieve robust real-time MR thermometry during clinical hepatic microwave ablations are described.•Quality Assurance protocol was…”
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Hepatitis C Virus Nonstructural Proteins Inhibit Apolipoprotein B100 Secretion
Published in The Journal of biological chemistry (02-12-2005)“…Host genes involved in lipid metabolism are differentially regulated during the early stages of hepatitis C virus (HCV) infection. The majority of lipids…”
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An investigation of the effects from a urethral warming system on temperature distributions during cryoablation treatment of the prostate: A phantom study
Published in Cryobiology (01-08-2014)“…Introduction of urethral warmers to aid cryosurgery in the prostate has significantly reduced the incidence of urethral sloughing; however, the incidence rate…”
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SU‐E‐I‐68: Preliminary Evaluation of Potential MRI Contrast Materials for the Purpose of MR‐Ultrasound Fusion Application in the Abdomen
Published in Medical Physics (01-06-2013)“…Purpose: To evaluate a variety of materials that might serve as fiducial markers for abdominal MRI‐ultrasound fusion applications. Methods: Two experiments…”
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Conference Proceeding Journal Article