Search Results - "Fellowes, V"

CD4 and CD8 T-cell positive selection increases the robustness of the CD22 CAR T-cell manufacturing process by Highfill, S.L, Jin, J, Fellowes, V, Ren, J, Ramakrishna, S, Fry, T, Stroncek, D

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Specific depletion of alloreactive T cells in HLA‐identical siblings: a method for separating graft‐versus‐host and graft‐versus‐leukaemia reactions by MAVROUDIS, D. A, DERMIME, S, MOLLDREM, J, JIANG, Y. Z, RAPTIS, A, VAN RHEE, F, HENSEL, N, FELLOWES, V, ELIOPOULOS, G, BARRETT, A. J

“…Accumulating evidence indicates that alloreactive donor T cells confer both graft‐versus‐host (GVH) and graft‐versus‐leukaemia (GVL) reactivity following…”
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Development of a closed system process for purifying naive CD8+ cells, culturing and transducing with a CD19/22 chimeric antigen receptor (CAR) to produce a clinical T memory stem cell product directed against B cell malignancies by Fellowes, V., Cai, Y., Rodriguez-Mesa, E., Grandinetti, P., Jin, J., Highfill, S.L., Schneider, D., Dropulic, B., Stroncek, D., Gress, R., Gattinoni, L.

“…Currently in the Center for Cellular Engineering at the National Institutes of Health, a clinical trial which involves purifying CD8+CD62L+CD45RA+ naïve T…”
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18 - CD4 and CD8 T-cell positive selection increases the robustness of the CD22 CAR T-cell manufacturing process by Highfill, S.L., Jin, J., Fellowes, V., Ren, J., Ramakrishna, S., Fry, T., Stroncek, D.

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Minimal residual disease detection in breast cancer: improved sensitivity using cytokeratin 19 and epidermal growth factor receptor RT-PCR by Fellowes, Vicki S, Husebekk, Anne, Gress, Ronald E, Vance, Barbara A

“…Breast cancer cells pose a difficult target for detection due to their lack of tumor specific markers. Small numbers of metastatic cells circulate through the…”
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Selection and expansion of T cell from untreated patients with CLL: source of cells for immune reconstitution? by Husebekk, A., Fellowes, V., Read, E. J., Williams, J., Petrus, M. J., Gress, R. E., Fowler, D. H.

“…Background: Lymphocyte-derived malignancies can be treated with combinations of drugs that efficiently eradicate normal and malignant lymphocytes. Lack of T…”
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Adoptive Infusion of Ex Vivo Expanded Autologous Natural Killer (NK) Cells in Cancer Patients Treated with Bortezomib to Sensitize to NK-TRAIL Cytotoxicity by Lundqvist, Andreas, Berg, M., Smith, A., Cook, L., Goodwin, R., Ramos, C., Vasu, S., Pantin, J., Lopez, R., Khuu, H., Fellowes, V., Stroncek, D., Donohue, T., Childs, R.

“…Abstract 4080 Poster Board III-1015 Ligation of inhibitory receptors renders natural killer (NK) cells inactive against autologous tumors. Recently, bortezomib…”
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Fas‐mediated lysis of chronic lymphocytic leukaemia cells: role of type I versus type II cytokines and autologous FasL‐expressing T cells by Williams, Jonathan F., Petrus, Matthew J., Wright, Jacob A., Husebekk, Anne, Fellowes, Vicki, Read, Elizabeth J., Gress, Ronald E., Fowler, Daniel H.

“…Given the known role of the fas cytolytic pathway in B‐cell regulation, we evaluated whether fas–fasL interactions might induce chronic lymphocytic leukaemia…”
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Immune Reconstitution in Recipients of Photodepleted HLA-identical Sibling Donor Stem Cell Transplants: T cell Subset Frequencies Predict Outcome by McIver, Z, Melenhorst, JJ, Grim, A, Naguib, N, Weber, G, Fellowes, V, Khuu, H, Stroncek, D, Leitman, S, Battiwalla, M, Barrett, AJ

“…We evaluated an ex-vivo photodepletion technique to selectively deplete graft-versus-host disease (GVHD) alloreacting T cells given to 24 HLA-identical sibling…”
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The Prophylactic Value of Scarlet Fever Antitoxin by Harries, E. H. R., Hervey, Dorothy, Fellowes, Vera

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Selectively T cell depleted allografts from HLA-matched sibling donors followed by low-dose post transplant immunosuppression to improve transplant outcome in patients with hematological malignancies by Mielke, S, McIver, Z, Shenoy, A, Fellowes, V, Khuu, H, Stroncek, DF, Leitman, SF, Childs, R, Battiwalla, M, Koklanaris, E, Haggerty, J, Savani, BN, Rezvani, K, Barrett, AJ

“…We evaluated a photodepletion technique to selectively deplete host-reacting T cells from HLA-matched sibling stem cell transplants with the goal of reducing…”
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Selection and expansion of T cells from untreated patients with CLL: source of cells for immune reconstitution? by Husebekk, A., Fellowes, V., Read, E.J., Williams, J., Petrus, M.J., Gress, R.E., Fowler, D.H.

“…Lymphocyte-derived malignancies can be treated with combinations of drugs that efficiently eradicate normal and malignant lymphocytes. Lack of T lymphocytes…”
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A novel strategy for selective depletion of host-reactive donor lymphocytes by photodepletion is efficient at clinical scale conditions and preserves foxp3+ regulatory T cells by Mielke, S., Rezvani, K., Fellowes, V., Venne, A., Solomon, S.R., Fan, Y., Hensel, N., Carter, C.S., Read, E.J., Barrett, A.J.

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Adoptive immunotherapy with tumor-derived donor lymphocytes after allogeneic hematopoietic stem cell transplantation by Hardy, N.M., Fellowes, V., Mariotti, J., Carter, C., June, C., Levine, B., Hakim, F., Vonderheide, R., Gress, R., Read, E.J., Fowler, D., Bishop, M.R.

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All Round the Mediterranean by R. N. R. B.

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