Search Results - "Fellner, Thomas"
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cGMP-Manufactured Human Induced Pluripotent Stem Cells Are Available for Pre-clinical and Clinical Applications
Published in Stem cell reports (13-10-2015)“…The discovery of induced pluripotent stem cells (iPSCs) and the concurrent development of protocols for their cell-type-specific differentiation have…”
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Journal Article -
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Detailed Characterization of Human Induced Pluripotent Stem Cells Manufactured for Therapeutic Applications
Published in Stem cell reviews (01-08-2016)“…We have recently described manufacturing of human induced pluripotent stem cells (iPSC) master cell banks (MCB) generated by a clinically compliant process…”
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Scalable passaging of adherent human pluripotent stem cells
Published in PloS one (30-01-2014)“…Current laboratory methods used to passage adherent human pluripotent stem cells (hPSCs) are labor intensive, result in reduced cell viability and are…”
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Human-Induced Pluripotent Stem Cells Manufactured Using a Current Good Manufacturing Practice-Compliant Process Differentiate Into Clinically Relevant Cells From Three Germ Layers
Published in Frontiers in medicine (15-03-2018)“…The discovery of reprogramming and generation of human-induced pluripotent stem cells (iPSCs) has revolutionized the field of regenerative medicine and opened…”
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A Newly Defined and Xeno-Free Culture Medium Supports Every-Other-Day Medium Replacement in the Generation and Long-Term Cultivation of Human Pluripotent Stem Cells
Published in PloS one (08-09-2016)“…Human pluripotent stem cells (hPSCs) present an unprecedented opportunity to advance human health by offering an alternative and renewable cell resource for…”
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Headcase promotes cell survival and niche maintenance in the Drosophila testis
Published in PloS one (09-07-2013)“…At the apical tip of the Drosophila testis, germline and somatic stem cells surround a cluster of somatic cells called the hub. Hub cells produce a…”
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Generation of active protein phosphatase 2A is coupled to holoenzyme assembly
Published in PLoS biology (01-06-2007)“…Protein phosphatase 2A (PP2A) is a prime example of the multisubunit architecture of protein serine/threonine phosphatases. Until substrate-specific PP2A…”
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Analysis of SOX2-Expressing Cell Populations Derived from Human Pluripotent Stem Cells
Published in Stem cell reports (19-11-2013)“…SOX2 is involved in several cell and developmental processes, including maintenance of embryonic stem cells, differentiation of neural progenitor cells, and…”
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A novel and essential mechanism determining specificity and activity of protein phosphatase 2A (PP2A) in vivo
Published in Genes & development (01-09-2003)“…Protein phosphatase 2A (PP2A) is an essential intracellular serine/threonine phosphatase containing a catalytic subunit that possesses the potential to…”
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Defining long-term maintenance conditions of human embryonic stem cells with arrayed cellular microenvironment technology
Published in Stem cells and development (01-10-2009)“…The optimization of defined growth conditions is necessary for the development of clinical application of human embryonic stem cells (hESCs). Current research…”
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Building bridges from research to therapy: a roadmap for the successful generation of clinical-grade iPSCs
Published in Cytotherapy (Oxford, England) (01-06-2015)Get full text
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Altering the holoenzyme composition and substrate specificity of protein phosphatase 2A
Published in Methods in enzymology (2003)Get more information
Journal Article -
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Parameter optimization of torque wireless sensors based on surface acoustic waves (SAW)
Published in 2012 13th International Thermal, Mechanical and Multi-Physics Simulation and Experiments in Microelectronics and Microsystems (01-04-2012)“…This paper demonstrates our approach for the design optimization of wireless torque sensor with FE simulation tools. Such a system comprises the SAW…”
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Conference Proceeding -
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Modelling of process and reliability of press-fit interconnections
Published in EuroSimE 2009 - 10th International Conference on Thermal, Mechanical and Multi-Physics Simulation and Experiments in Microelectronics and Microsystems (01-04-2009)“…This investigation is aimed at the stability of press-fit interconnections for MID. Moulded interconnect devices (MID) are 3-dimensional substrates produced by…”
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Conference Proceeding -
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Analyzing Parameters Influencing Stress and Drift in Moulded Hall Sensors
Published in 2006 1st Electronic Systemintegration Technology Conference (01-09-2006)“…sensor is described. The geometry of the device, the behaviour of the packaging materials as well as the packaging process are regarded using this method. The…”
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Conference Proceeding