Search Results - "Fellgiebel, Andreas"

Diffusion tensor imaging of the hippocampus in MCI and early Alzheimer's disease by Fellgiebel, Andreas, Yakushev, Igor

“…The hippocampus is among the first brain structures to be affected by Alzheimer's disease (AD) pathology. Microstructural alterations within this region have…”
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Multimodal imaging in Alzheimer's disease: validity and usefulness for early detection by Teipel, Stefan, Dr, Drzezga, Alexander, MD, Grothe, Michel J, PhD, Barthel, Henryk, MD, Chételat, Gaël, PhD, Schuff, Norbert, PhD, Skudlarski, Pawel, PhD, Cavedo, Enrica, MS, Frisoni, Giovanni B, MD, Hoffmann, Wolfgang, MD, Thyrian, Jochen René, PhD, Fox, Chris, MD, Minoshima, Satoshi, MD, Sabri, Osama, MD, Fellgiebel, Andreas, MD

“…Summary Alzheimer's disease is a progressive neurodegenerative disease that typically manifests clinically as an isolated amnestic deficit that progresses to a…”
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Altered whole-brain white matter networks in preclinical Alzheimer's disease by Fischer, Florian Udo, Wolf, Dominik, Scheurich, Armin, Fellgiebel, Andreas

“…Surrogates of whole-brain white matter (WM) networks reconstructed using diffusion tensor imaging (DTI) are novel markers of structural brain connectivity…”
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Influence of loss- and restoration-oriented stressors on grief in times of COVID-19 by Palm, Svenja, Doering, Bettina K., Kubiak, Thomas, Geschke, Katharina, Fellgiebel, Andreas, Wuttke, Alexandra

“…This study aimed to examine the influence of COVID-specific stressors on cross-sectional and longitudinal bereavement outcomes. According to the Dual Process…”
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Association of structural global brain network properties with intelligence in normal aging by Fischer, Florian U, Wolf, Dominik, Scheurich, Armin, Fellgiebel, Andreas

“…Higher general intelligence attenuates age-associated cognitive decline and the risk of dementia. Thus, intelligence has been associated with cognitive reserve…”
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Public knowledge and attitudes about mental health in older age in Germany – Focus on dementia and late-life depression by Wuttke, Alexandra, Palm, Svenja, Geschke, Katharina, Fellgiebel, Andreas

“…Older people with mental disorders represent a particularly vulnerable group in the health care system. Despite this, mental disorders in this group often…”
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The Influence of Resilience on Caregiver Burden, Depression, and Stress in the Course of the COVID-19 Lockdowns by Geschke, Katharina, Steinmetz, Annika, Fellgiebel, Andreas, Wuttke-Linnemann, Alexandra

“…The COVID-19 pandemic has brought unique challenges for caregivers. This study examines whether individual resilience accounted for differences in caregiver…”
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The relationship between interhemispheric transfer time and physical activity as well as cardiorespiratory fitness in healthy older adults by Riedel, David, Lorke, Nicolai, Mierau, Andreas, Strüder, Heiko K., Wolf, Dominik, Fischer, Florian, Fellgiebel, Andreas, Tüscher, Oliver, Kollmann, Bianca, Knaepen, Kristel

“…The structural and functional degradation of the corpus callosum (CC) has been shown to play an important role in the context of cognitive aging (Reuter-Lorenz…”
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NrCAM is a marker for substrate‐selective activation of ADAM10 in Alzheimer's disease by Brummer, Tobias, Müller, Stephan A, Pan‐Montojo, Francisco, Yoshida, Fumiaki, Fellgiebel, Andreas, Tomita, Taisuke, Endres, Kristina, Lichtenthaler, Stefan F

“…The metalloprotease ADAM10 is a drug target in Alzheimer's disease, where it cleaves the amyloid precursor protein (APP) and lowers amyloid‐beta. Yet, ADAM10…”
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Robust automated detection of microstructural white matter degeneration in Alzheimer's disease using machine learning classification of multicenter DTI data by Dyrba, Martin, Ewers, Michael, Wegrzyn, Martin, Kilimann, Ingo, Plant, Claudia, Oswald, Annahita, Meindl, Thomas, Pievani, Michela, Bokde, Arun L W, Fellgiebel, Andreas, Filippi, Massimo, Hampel, Harald, Klöppel, Stefan, Hauenstein, Karlheinz, Kirste, Thomas, Teipel, Stefan J

“…Diffusion tensor imaging (DTI) based assessment of white matter fiber tract integrity can support the diagnosis of Alzheimer's disease (AD). The use of DTI as…”
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Introduction and Psychometric Validation of the Resilience and Strain Questionnaire (ResQ-Care)- A Scale on the Ratio of Informal Caregivers' Resilience and Stress Factors by Wuttke-Linnemann, Alexandra, Palm, Svenja, Scholz, Lea, Geschke, Katharina, Fellgiebel, Andreas

“…Informal caregivers are a particularly vulnerable population at risk for adverse health outcomes. Likewise, there are many scales available assessing…”
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Cognitive reserve impacts on inter-individual variability in resting-state cerebral metabolism in normal aging by Bastin, Christine, Yakushev, Igor, Bahri, Mohamed Ali, Fellgiebel, Andreas, Eustache, Francis, Landeau, Brigitte, Scheurich, Armin, Feyers, Dorothée, Collette, Fabienne, Chételat, Gael, Salmon, Eric

“…There is a great deal of heterogeneity in the impact of aging on cognition and cerebral functioning. One potential factor contributing to individual…”
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Relationships between brain metabolism decrease in normal aging and changes in structural and functional connectivity by Chételat, Gaël, Landeau, Brigitte, Salmon, Eric, Yakushev, Igor, Bahri, Mohamed Ali, Mézenge, Florence, Perrotin, Audrey, Bastin, Christine, Manrique, Alain, Scheurich, Armin, Scheckenberger, Mathias, Desgranges, Béatrice, Eustache, Francis, Fellgiebel, Andreas

“…Normal aging is characterized by brain glucose metabolism decline predominantly in the prefrontal cortex. The goal of the present study was to assess whether…”
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Non-Linear Association between Cerebral Amyloid Deposition and White Matter Microstructure in Cognitively Healthy Older Adults by Wolf, Dominik, Fischer, Florian U, Scheurich, Armin, Fellgiebel, Andreas

“…Cerebral amyloid-β accumulation and changes in white matter (WM) microstructure are imaging characteristics in clinical Alzheimer's disease and have also been…”
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Structural Network Efficiency Predicts Resilience to Cognitive Decline in Elderly at Risk for Alzheimer's Disease by Fischer, Florian U, Wolf, Dominik, Tüscher, Oliver, Fellgiebel, Andreas

“…: Functional imaging studies have demonstrated the recruitment of additional neural resources as a possible mechanism to compensate for age and Alzheimer's…”
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Psychobiological Evaluation of Day Clinic Treatment for People Living With Dementia – Feasibility and Pilot Analyses by Wuttke-Linnemann, Alexandra, Palm, Svenja, Geschke, Katharina, Skoluda, Nadine, Bischoff, Theresa, Nater, Urs M., Endres, Kristina, Fellgiebel, Andreas

“…Background Hospitalization is often stressful and burdensome for people living with dementia (PwD) and their informal caregivers (ICs). Day clinic treatment…”
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Enzyme replacement therapy stabilized white matter lesion progression in Fabry disease by Fellgiebel, Andreas, Gartenschläger, Martin, Wildberger, Kerstin, Scheurich, Armin, Desnick, Robert J, Sims, Katherine

“…The central nervous system manifestations in Fabry disease (FD) include progressive white matter lesions (WMLs) and stroke. Due to progressive microvascular…”
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Dorsolateral Prefrontal Functional Connectivity Predicts Working Memory Training Gains by Faraza, Sofia, Waldenmaier, Julia, Dyrba, Martin, Wolf, Dominik, Fischer, Florian U, Knaepen, Kristel, Kollmann, Bianca, Tüscher, Oliver, Binder, Harald, Mierau, Andreas, Riedel, David, Fellgiebel, Andreas, Teipel, Stefan

“…Normal aging is associated with working memory decline. A decrease in working memory performance is associated with age-related changes in functional…”
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Eight-Year Follow-Up of Neuropsychiatric Symptoms and Brain Structural Changes in Fabry Disease by Lelieveld, Irene M, Böttcher, Anna, Hennermann, Julia B, Beck, Michael, Fellgiebel, Andreas

“…Brain structural alterations and neuropsychiatric symptoms have been described repeatedly in Fabry disease, yet cognitive deficits have been shown to be only…”
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The Synthetic Retinoid Acitretin Increases IL-6 in the Central Nervous System of Alzheimer Disease Model Mice and Human Patients by Dos Santos Guilherme, Malena, Stoye, Nicolai M, Rose-John, Stefan, Garbers, Christoph, Fellgiebel, Andreas, Endres, Kristina

“…These days, the important role of retinoids in adult brain functionality and homeostasis is well accepted and has been proven by genomic as well as non-genomic…”
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