Search Results - "Fell, J.T"

Pectin/chitosan mixtures as coatings for colon-specific drug delivery: an in vitro evaluation by Fernández-Hervás, M.J, Fell, J.T

“…The ability of a multiple-unit dosage form to reach the colon intact has been investigated, in vitro, using conditions chosen to simulate the pH and times…”
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In vitro evaluation of alginate beads of a diclofenac salt by Fernández-Hervás, M.J, Holgado, M.A, Fini, A, Fell, J.T

“…Alginate beads containing diclofenac hydroxyethylpyrrolidine were formulated with either Eudragit or chitosan in order to achieve an enteric formulation. In…”
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The wetting of powders by bile salt solutions and gastric juice by Fell, J.T., Mohammad, H.A.H.

“…Contact angle studies using bile salt solutions and gastric juice have been carried out on phenobarbitone, a model hydrophobic powder. Interpretation of the…”
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Influence of pectin and calcium pectinate films on in vitro drug release from coated theophylline pellets by Wanasawas, P., Sinchaipanid, N., Fell, J.T., Mitrevej, A.

“…The aim of this study was to investigate the in vitro drug-release behavior of theophylline pellets coated with different films, pectin or calcium pectinate…”
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Floating dosage forms: an in vivo study demonstrating prolonged gastric retention by Whitehead, L., Fell, J.T., Collett, J.H., Sharma, H.L., Smith, A.-M.

“…Gastroretentive dosage forms have potential for use as controlled-release drug delivery systems. The use of floating dosage forms (FDFs) is one method to…”
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An investigation of the disintegration of tablets in biorelevant media by Anwar, S., Fell, J.T., Dickinson, P.A.

“…The purpose of the study was to examine the disintegration of tablets in media designed to simulate conditions pertaining in the stomach. Although many studies…”
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Hydrogel beads based on amidated pectins for colon-specific drug delivery: the role of chitosan in modifying drug release by Munjeri, O, Collett, J.H, Fell, J.T

“…A multiparticulate system with the potential for site-specific delivery to the colon has been investigated. Gelation of droplets of amidated pectin solutions…”
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Effect of particle size and speed of compaction on density changes in tablets of crystalline and spray-dried lactose by Fell, J T, Newton, J M

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Contact angles and wetting of pharmaceutical powders by Lerk, C F, Schoonen, A J, Fell, J T

“…Contact angles of pharmaceutical powders were determined by the h-epsilon method, which consists essentially of measuring the maximum height of a drop of…”
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In vivo evaluation of a novel gastric retentive formulation based on ion exchange resins by Atyabi, F., Sharma, H.L., Mohammad, H.A.H., Fell, J.T.

“…Systems that exhibit gastric retention are of value in several areas of therapy. A novel floating system based on ion exchange resins has been investigated and…”
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Studies on drug release from pectin/ethylcellulose film-coated tablets: a potential colonic delivery system by Wakerly, Z, Fell, J.T, Attwood, D, Parkins, D

“…Combinations of pectin and ethylcellulose, when applied as a film coat, have potential value as a colonic delivery system. Aqueous dispersions of pectin and…”
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Controlled drug release from coated floating ion exchange resin beads by Atyabi, F., Sharma, H.L., Mohammad, H.A.H., Fell, J.T.

“…Ion exchange resin beads can be loaded with bicarbonate and coated with a semipermeable membrane. These beads exhibit prolonged gastric residence due to…”
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Development of gastroretentive dosage form by Whishead, L., Fell, J.T., Collett, J.H.

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Production and characterisation of enteric beads by Zaniboni, H.C., Fell, J.T., Collett, J.H.

“…Enteric beads have been produced using a purely aqueous system. The method relies on the precipitation of the enteric polymer hydroxypropylmethylcellulose…”
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Determination of tablet strength by the diametral-compression test by Fell, J T, Newton, J M

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Effect of aging on physical properties of phenylbutazone tablets by Barrett, D, Fell, J T

“…A study was made of the influence of age on the physical properties of phenylbutazone tablets BP, with special reference to in vitro dissolution rates. Past…”
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Effect of hydrophilization of hydrophobic drugs on release rate from capsules by Lerk, C F, Lagas, M, Fell, J T, Nauta, P

“…The release of poorly soluble hydrophobic drugs from capsules can be improved significantly by the creation of a hydrophilic surface by intensive mixing of the…”
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The in vivo disintegration of hard gelatin capsules [proceedings] by Hunter, E, Calvert, R T, Fell, J T

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The tableting of dental cement powders by Fell, J T, Combe, E C

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Assessment of compression characteristics of powders by Fell, J T, Newton, J M

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