Search Results - "Felker, Allison M"
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The relationship between sex hormones, the vaginal microbiome and immunity in HIV-1 susceptibility in women
Published in Disease models & mechanisms (01-09-2018)“…The role of sex hormones in regulating immune responses in the female genital tract has been recognized for decades. More recently, it has become increasingly…”
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Uterine natural killer cells: supervisors of vasculature construction in early decidua basalis
Published in Reproduction (Cambridge, England) (01-02-2015)“…Mammalian pregnancy involves tremendous de novo maternal vascular construction to adequately support conceptus development. In early mouse decidua basalis…”
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Primary HSV-2 Infection in Early Pregnancy Results in Transplacental Viral Transmission and Dose-Dependent Adverse Pregnancy Outcomes in a Novel Mouse Model
Published in Viruses (25-09-2021)“…Herpes simplex virus type 2 (HSV-2) infection affects 24 million births annually and is associated with adverse pregnancy outcomes, including neonatal herpes;…”
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Depot medroxyprogesterone acetate (DMPA) enhances susceptibility and increases the window of vulnerability to HIV-1 in humanized mice
Published in Scientific reports (16-02-2021)“…The progestin-based hormonal contraceptive Depot Medroxyprogesterone Acetate (DMPA) is widely used in sub-Saharan Africa, where HIV-1 is endemic. Meta-analyses…”
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Medroxyprogesterone acetate alters the vaginal microbiota and microenvironment in women and increases susceptibility to HIV-1 in humanized mice
Published in Disease models & mechanisms (01-10-2019)“…The hormonal contraceptive medroxyprogesterone acetate (MPA) is associated with increased risk of human immunodeficiency virus (HIV), via incompletely…”
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Uterine natural killer cell partnerships in early mouse decidua basalis
Published in Journal of leukocyte biology (01-10-2016)“…Percentage of leukocytes in mouse decidua basalis are conjugated after blastocyst implantation; dominating uNK cells partner with APCs, then CD8+ T cells. The…”
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Male fetal sex affects uteroplacental angiogenesis in growth restriction mouse model
Published in Biology of reproduction (01-04-2021)“…Abstract Abnormally increased angiotensin II activity related to maternal angiotensinogen (AGT) genetic variants, or aberrant receptor activation, is…”
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The Transcription Factor NFIL3 Is Essential for Normal Placental and Embryonic Development but Not for Uterine Natural Killer (UNK) Cell Differentiation in Mice
Published in Biology of reproduction (01-05-2016)“…Mice ablated for the gene encoding the transcription factor Nfil3 lack peripheral natural killer (NK) cells but retain tissue-resident NK cells, particularly…”
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The Transcription Factor NFIL3 Is Essential for Normal Placental and Embryonic Development but Not for Uterine Natural Killer (UNK) Cell Differentiation in Mice1
Published in Biology of reproduction (01-05-2016)“…Mice ablated for the gene encoding the transcription factor Nfil3 lack peripheral natural killer (NK) cells but retain tissue-resident NK cells, particularly…”
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Ly49 knockdown in mice results in aberrant uterine crypt formation and impaired blastocyst implantation
Published in Placenta (Eastbourne) (01-03-2016)“…Abstract Genetic knockdown (KD) of the mouse Ly49 receptor family is reported to result in infertility despite the presence of zona-enclosed blastocysts in the…”
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Promotion of Early Pregnancy Events in Mice and Humans by Uterine Natural Killer Cells
Published in Neoreviews (Elk Grove Village, Ill.) (01-02-2016)“…Mammalian pregnancy is a unique immunologic situation in which the maternal immune system recognizes and accepts an antigenically disparate tissue, the…”
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