Search Results - "Felisbino, Marina B."
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Histone epigenetic marks in heterochromatin and euchromatin of the Chagas’ disease vector, Triatoma infestans
Published in Acta histochemica (01-05-2016)“…•Epigenetic marks were compared in different chromatin territories of T. infestans.•Immunocytochemical and image analysis methods were used.•Modified histones…”
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Epigenetics in Cardiac Fibrosis: Emphasis on Inflammation and Fibroblast Activation
Published in JACC. Basic to translational science (01-10-2018)“…Chemical modifications to nucleosomal DNA and histone tails greatly influence transcription of adjacent and distant genes, a mode of gene regulation referred…”
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Dynamic Chromatin Targeting of BRD4 Stimulates Cardiac Fibroblast Activation
Published in Circulation research (13-09-2019)“…RATIONALE:Small molecule inhibitors of the acetyl-histone binding protein BRD4 have been shown to block cardiac fibrosis in preclinical models of heart failure…”
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Substrate stiffness modulates cardiac fibroblast activation, senescence, and proinflammatory secretory phenotype
Published in American journal of physiology. Heart and circulatory physiology (01-01-2024)“…In vitro cultures of primary cardiac fibroblasts (CFs), the major extracellular matrix (ECM)-producing cells of the heart, are used to determine molecular…”
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Inhibition of Eicosanoid Degradation Mitigates Fibrosis of the Heart
Published in Circulation research (06-01-2023)“…Organ fibrosis due to excessive production of extracellular matrix by resident fibroblasts is estimated to contribute to >45% of deaths in the Western world,…”
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6
Epigenetics in Cardiac Fibrosis
Published in JACC. Basic to translational science (01-10-2018)“…Summary Chemical modifications to nucleosomal DNA and histone tails greatly influence transcription of adjacent and distant genes, a mode of gene regulation…”
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Image analysis of chromatin remodelling
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2014)“…Chromatin packaging plays a significant role in regulating gene transcription. Study of the higher-order packing states of chromatin by image analysis at the…”
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8
Inhibition of Eicosanoid Degradation Mitigates Fibrosis of the Heart
Published in Circulation research (08-12-2022)Get full text
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9
Chromatin remodeling induced by histone deacetylase inhibitors (HDACis) in HeLa, NIH 3T3 and HepG2 cells
Published in Epigenetics & chromatin (18-03-2013)“…Doc number: P17…”
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