Search Results - "Feliciano, Joana"

Small Noncoding Regulatory RNAs from Pseudomonas aeruginosa and Burkholderia cepacia Complex by Pita, Tiago, Feliciano, Joana R, Leitão, Jorge H

“…Cystic fibrosis (CF) is the most life-limiting autosomal recessive disorder in Caucasians. CF is characterized by abnormal viscous secretions that impair the…”
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Identification of Burkholderia cenocepacia non-coding RNAs expressed during Caenorhabditis elegans infection by Pita, Tiago, Feliciano, Joana R., Leitão, Jorge H.

“…Small non-coding RNAs (sRNAs) are key regulators of post-transcriptional gene expression in bacteria. Despite the identification of hundreds of bacterial…”
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Non-coding regulatory sRNAs from bacteria of the Burkholderia cepacia complex by Matos, Gonçalo R., Feliciano, Joana R., Leitão, Jorge H.

“…Small non-coding RNAs (sRNAs) are key regulators of post-transcriptional gene expression in bacteria. Hundreds of sRNAs have been found using in silico genome…”
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Macrophages, but not neutrophils, are critical for proliferation of Burkholderia cenocepacia and ensuing host-damaging inflammation by Mesureur, Jennifer, Feliciano, Joana R, Wagner, Nelly, Gomes, Margarida C, Zhang, Lili, Blanco-Gonzalez, Monica, van der Vaart, Michiel, O'Callaghan, David, Meijer, Annemarie H, Vergunst, Annette C

“…Bacteria of the Burkholderia cepacia complex (Bcc) can cause devastating pulmonary infections in cystic fibrosis (CF) patients, yet the precise mechanisms…”
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Extracellular RNAs in Bacterial Infections: From Emerging Key Players on Host-Pathogen Interactions to Exploitable Biomarkers and Therapeutic Targets by Pita, Tiago, Feliciano, Joana R, Leitão, Jorge H

“…Non-coding RNAs (ncRNAs) are key regulators of post-transcriptional gene expression in prokaryotic and eukaryotic organisms. These molecules can interact with…”
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The afc antifungal activity cluster, which is under tight regulatory control of ShvR, is essential for transition from intracellular persistence of Burkholderia cenocepacia to acute pro-inflammatory infection by Gomes, Margarida C, Tasrini, Yara, Subramoni, Sujatha, Agnoli, Kirsty, Feliciano, Joana R, Eberl, Leo, Sokol, Pamela, O'Callaghan, David, Vergunst, Annette C

“…The opportunistic pathogen Burkholderia cenocepacia is particularly life-threatening for cystic fibrosis (CF) patients. Chronic lung infections with these…”
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Advances in Human Pathogen Control—A 21st Century Challenge by Leitão, Jorge H, Feliciano, Joana R, Amdare, Nitin

“…The emergence of new pathogens, coupled with the reemergence of old pathogens and the steep worldwide increase in multiple resistances to available…”
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Experience from an evidence-based journey with digital automation for heart failure outpatient management in a Portuguese hospital by Ladeiras-Lopes, Ricardo, Jasmins, Clara, Fonseca, Válter, Feliciano, Joana, Rodrigues, David

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Burkholderia cepacia Complex Regulation of Virulence Gene Expression: A Review by Sousa, Sílvia A, Feliciano, Joana R, Pita, Tiago, Guerreiro, Soraia I, Leitão, Jorge H

“…complex (Bcc) bacteria emerged as opportunistic pathogens in cystic fibrosis and immunocompromised patients. Their eradication is very difficult due to the…”
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Correction: Macrophages, but not neutrophils, are critical for proliferation of Burkholderia cenocepacia and ensuing host-damaging inflammation by Mesureur, Jennifer, Feliciano, Joana R, Wagner, Nelly, Gomes, Margarida C, Zhang, Lili, Blanco-Gonzalez, Monica, van der Vaart, Michiel, O'Callaghan, David, Meijer, Annemarie H, Vergunst, Annette C

“…[This corrects the article DOI: 10.1371/journal.ppat.1006437.]…”
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Bacterial Nosocomial Infections: Multidrug Resistance as a Trigger for the Development of Novel Antimicrobials by Sousa, Sílvia A., Feliciano, Joana R., Pita, Tiago, Soeiro, Catarina F., Mendes, Beatriz L., Alves, Luis G., Leitão, Jorge H.

“…Nosocomial bacterial infections are associated with high morbidity and mortality, posing a huge burden to healthcare systems worldwide. The ongoing COVID-19…”
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Surface-Exposed Protein Moieties of Burkholderia cenocepacia J2315 in Microaerophilic and Aerobic Conditions by Seixas, António M M, Silva, Carolina, Marques, Joana M M, Mateus, Patrícia, Rodríguez-Ortega, Manuel J, Feliciano, Joana R, Leitão, Jorge H, Sousa, Sílvia A

“…complex infections remain life-threatening to cystic fibrosis patients, and due to the limited eradication efficiency of current treatments, novel…”
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Regulation of Hfq mRNA and protein levels in Escherichia coli and Pseudomonas aeruginosa by the Burkholderia cenocepacia MtvR sRNA by Ramos, Christian G, Grilo, André M, Sousa, Sílvia A, Feliciano, Joana R, da Costa, Paulo J P, Leitão, Jorge H

“…Small non-coding RNAs (sRNAs) are important players of gene expression regulation in bacterial pathogens. MtvR is a 136-nucleotide long sRNA previously…”
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Synthesis, antimicrobial activity and toxicity to nematodes of cyclam derivatives by Alves, Luis G, Pinheiro, Pedro F, Feliciano, Joana R, Dâmaso, Diana P, Leitão, Jorge H, Martins, Ana M

“…Highlights • Synthesis and antimicrobial activity of cyclam derivatives is described. • Cyclam [H2 {H2 (4-CF3 PhCH2 )2 Cyclam}](CH3 COO)2 .(CH3 COOH)2 has…”
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Biochemical and functional studies on the Burkholderia cepacia complex bceN gene, encoding a GDP-D-mannose 4,6-dehydratase by Sousa, Sílvia A, Feliciano, Joana R, Pinheiro, Pedro F, Leitão, Jorge H

“…This work reports the biochemical and functional analysis of the Burkholderia cenocepacia J2315 bceN gene, encoding a protein with GDP-D-mannose…”
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Hfq: a multifaceted RNA chaperone involved in virulence by Feliciano, Joana R, Grilo, André M, Guerreiro, Soraia I, Sousa, Sílvia A, Leitão, Jorge H

“…Hfq has emerged in recent years as a master regulator of gene expression in bacteria, mainly due to its ability to mediate the interaction of small noncoding…”
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New insights into the immunoproteome of B. cenocepacia J2315 using serum samples from cystic fibrosis patients by Sousa, Sílvia A., Soares-Castro, Pedro, Seixas, António M.M., Feliciano, Joana R., Balugas, Bernardo, Barreto, Celeste, Pereira, Luísa, Santos, Pedro M., Leitão, Jorge H.

“…•24 immunoreactive proteins from Burkholderia cenocepacia J2315 were identified.•19 out of the 24 proteins were found as immunoreactive for the first time.•5…”
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Suitability of a Saccharomyces cerevisiae-based assay to assess the toxicity of pyrimethanil sprayed soils via surface runoff: Comparison with standard aquatic and soil toxicity assays by Gil, Fátima N., Moreira-Santos, Matilde, Chelinho, Sónia, Pereira, Carla, Feliciano, Joana R., Leitão, Jorge H., Sousa, José P., Ribeiro, Rui, Viegas, Cristina A.

“…The present study is aimed at evaluating whether a gene expression assay with the microbial eukaryotic model Saccharomyces cerevisiae could be used as a…”
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A Polyclonal Antibody Raised against the Burkholderia cenocepacia OmpA-like Protein BCAL2645 Impairs the Bacterium Adhesion and Invasion of Human Epithelial Cells In Vitro by Seixas, António M M, Sousa, Sílvia A, Feliciano, Joana R, Gomes, Sara C, Ferreira, Mirela R, Moreira, Leonilde M, Leitão, Jorge H

“…Respiratory infections by bacteria of the complex (Bcc) remain a life threat to cystic fibrosis (CF) patients, due to the faster lung function decline and the…”
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Comparative Genomics and Evolutionary Analysis of RNA-Binding Proteins of Burkholderia cenocepacia J2315 and Other Members of the B. cepacia Complex by Feliciano, Joana R, Seixas, António M M, Pita, Tiago, Leitão, Jorge H

“…RNA-binding proteins (RBPs) are important regulators of cellular functions, playing critical roles on the survival of bacteria and in the case of pathogens, on…”
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