Search Results - "Felicella, Michelle"
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System-based integrated metabolomics and microRNA analysis identifies potential molecular alterations in human X-linked cerebral adrenoleukodystrophy brain
Published in Human molecular genetics (17-11-2023)“…Abstract X-linked adrenoleukodystrophy is a severe demyelinating neurodegenerative disease mainly affecting males. The severe cerebral adrenoleukodystrophy…”
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Discordant inheritance of chromosomal and extrachromosomal DNA elements contributes to dynamic disease evolution in glioblastoma
Published in Nature genetics (01-05-2018)“…To understand how genomic heterogeneity of glioblastoma (GBM) contributes to poor therapy response, we performed DNA and RNA sequencing on GBM samples and the…”
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Recent Advances in the Classification and Treatment of Ependymomas
Published in Current treatment options in oncology (01-09-2017)“…Opinion Statement Ependymomas are a subgroup of ependymal glia-derived neoplasms that affect children as well as adults. Arising within any CNS compartment,…”
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Metformin‐induced mitochondrial function and ABCD2 up‐regulation in X‐linked adrenoleukodystrophy involves AMP‐activated protein kinase
Published in Journal of neurochemistry (01-07-2016)“…X‐linked adrenoleukodystrophy (X‐ALD) is a progressive neurometabolic disease caused by mutations/deletions in the Abcd1 gene. Similar mutations/deletions in…”
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A wireless millimetric magnetoelectric implant for the endovascular stimulation of peripheral nerves
Published in Nature biomedical engineering (01-06-2022)“…Implantable bioelectronic devices for the simulation of peripheral nerves could be used to treat disorders that are resistant to traditional pharmacological…”
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Improved immunostaining of nanostructures and cells in human brain specimens through expansion-mediated protein decrowding
Published in Science translational medicine (31-01-2024)“…Proteins are densely packed in cells and tissues, where they form complex nanostructures. Expansion microscopy (ExM) variants have been used to separate…”
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Multifocal Intradural Extramedullary Pilocytic Astrocytomas of the Spinal Cord: A Case Report and Review of the Literature
Published in Neurosurgery (01-02-2017)“…Abstract BACKGROUND AND IMPORTANCE: Pilocytic astrocytoma (PA) is among the most common of the central nervous system gliomas in the pediatric population;…”
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Clinical, pathologic, and imaging characteristics of pituitary null cell adenomas as defined according to the 2017 World Health Organization criteria: a case series from two pituitary centers
Published in Pituitary (01-10-2019)“…Purpose The 2017 World Health Organization classification of pituitary tumors redefined pituitary null cell adenomas (NCAs) by restricting this diagnostic…”
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Diagnostic implications of IDH1-R132H and OLIG2 expression patterns in rare and challenging glioblastoma variants
Published in Modern pathology (01-03-2013)“…Recent work has demonstrated that nearly all diffuse gliomas display nuclear immunoreactivity for the bHLH transcription factor OLIG2, and the R132H mutant…”
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Eosinophilic myenteric ganglionitis: A case in a 14‐year‐old‐male
Published in JPGN reports (01-08-2024)“…Chronic intestinal pseudo‐obstruction (CIPO) is a rare, severe, and often debilitating condition that can result in significant morbidity and mortality amongst…”
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Necrotizing Plasma Cell-Rich Aortitis and Sudden Cardiac Death: Late Sequelae of COVID-19?
Published in Cardiovascular pathology (01-09-2023)“…•SARS-CoV-2 infection resulted in a unique plasma cell-rich necrotizing aortitis.•Long-term aortic complication of COVID-19.•Most of the aortic intima,…”
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Interdural course of the ophthalmic artery in the optic canal
Published in Journal of neurosurgery (01-01-2020)“…In the current neurosurgical and anatomical literature, the intracanalicular segment of the ophthalmic artery (OphA) is usually described to be within the…”
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Awake resection of recurrent astroblastoma with intraoperative 5-ALA–induced fluorescence: illustrative case
Published in Journal of neurosurgery. Case lessons (30-10-2023)“…BACKGROUND Astroblastoma is a rare neoplasm characterized as a circumscribed glial neoplasm most often arising in the frontoparietal cerebral hemispheres in…”
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A Case of Radiologically Compatible Chronic Lymphocytic Inflammation With Pontine Perivascular Enhancement Responsive to Steroids (CLIPPERS) With Demyelinating Lesions
Published in Curēus (Palo Alto, CA) (05-08-2023)“…Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is a recently identified diagnosis that can cause a…”
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A Fatal Fungal Infection: Cryptococcus gattii (VGI) Meningitis in Texas
Published in Open forum infectious diseases (01-07-2022)“…Abstract Cryptococcus gattii is an underrecognized cause of meningitis, especially in nonendemic regions. This report details C gattii disease progression from…”
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Endocisternal interfaces for minimally invasive neural stimulation and recording of the brain and spinal cord
Published in Nature biomedical engineering (11-11-2024)“…Minimally invasive neural interfaces can be used to diagnose, manage and treat many disorders, with reduced risks of surgical complications. However,…”
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Cystic Trophoblastic Tumor in a Primary Central Nervous System Post-Chemotherapy Germ Cell Tumor: The First Case Report
Published in International journal of surgical pathology (01-12-2020)“…Cystic trophoblastic tumor (CTT) is an uncommon trophoblastic proliferation of germ cell tumor origin, mostly reported in post-chemotherapy metastases of…”
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A sensitive and specific histopathologic prognostic marker for H3F3A K27M mutant pediatric glioblastomas
Published in Acta neuropathologica (01-11-2014)“…Pediatric glioblastomas (GBM) are highly aggressive and lethal tumors. Recent sequencing studies have shown that ~30 % of pediatric GBM and ~80 % of diffuse…”
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Isolated Ocular Manifestation of Relapsed Chronic Myelogenous Leukemia Presenting as Myeloid Blast Crisis in a Patient on Imatinib Therapy: A Case Report and Review of the Literature
Published in Case reports in pathology (01-01-2015)“…Blast phase in chronic myelogenous leukemia (CML) has rarely been reported to involve extramedullary sites like skin, lymph nodes, and central nervous system…”
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