Search Results - "Felice, Peter A"

Role of parathyroid hormone in regeneration of irradiated bone in a murine model of mandibular distraction osteogenesis by Kang, Stephen Y., Deshpande, Sagar S., Zheutlin, Alexander R., Donneys, Alexis, Rodriguez, Jose J., Nelson, Noah S., Felice, Peter A., Chepeha, Douglas B., Buchman, Steven R.

“…Background The purpose of this study was to measure the histologic and histomorphometric effects of parathyroid hormone (PTH) treatment on irradiated bone…”
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Parathyroid hormone reverses radiation induced hypovascularity in a murine model of distraction osteogenesis by Kang, Stephen Y, Deshpande, Sagar S, Donneys, Alexis, Rodriguez, Jose J, Nelson, Noah S, Felice, Peter A, Chepeha, Douglas B, Buchman, Steven R

“…Abstract Background Radiation treatment results in a severe diminution of osseous vascularity. Intermittent parathyroid hormone (PTH) has been shown to have an…”
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Quantification and Characterization of Radiation-Induced Changes to Mandibular Vascularity Using Micro–Computed Tomography by Deshpande, Sagar Satish, Donneys, Alexis, Farberg, Aaron Samuel, Tchanque-Fossuo, Catherine N, Felice, Peter A, Buchman, Steven Richard

“…OBJECTIVEPerhaps the most vexing and exigent problem confronting head and neck cancer reconstruction is overcoming the impediments of collateral damage imposed…”
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Raman spectroscopy delineates radiation-induced injury and partial rescue by amifostine in bone: a murine mandibular model by Felice, Peter A., Gong, Bo, Ahsan, Salman, Deshpande, Sagar S., Nelson, Noah S., Donneys, Alexis, Tchanque-Fossuo, Catherine, Morris, Michael D., Buchman, Steven R.

“…Despite its therapeutic role in head and neck cancer, radiation administration degrades the biomechanical properties of bone and can lead to pathologic…”
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A Comparison of Vascularity, Bone Mineral Density Distribution, and Histomorphometrics in an Isogenic Versus an Outbred Murine Model of Mandibular Distraction Osteogenesis by Carey, Edward G., B.A, Deshpande, Sagar S., B.S, Zheutlin, Alexander R., B.S, Nelson, Noah S., B.S, Donneys, Alexis, M.D., M.S, Kang, Stephen Y., M.D, Gallagher, Kathleen K., M.D, Felice, Peter A., M.D, Tchanque-Fossuo, Catherine N., M.D., M.S, Buchman, Steven R., M.D

“…Abstract Background Vascularity, bone mineral density distribution, and histomorphometrics between the inbred, isogenic Lewis rat and the outbred, nonisogenic…”
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Deferoxamine Administration Delivers Translational Optimization of Distraction Osteogenesis in the Irradiated Mandible by Felice, Peter A., Ahsan, Salman, Donneys, Alexis, Deshpande, Sagar S., Nelson, Noah S., Buchman, Steven R.

“…The authors' laboratory has previously demonstrated that deferoxamine promotes angiogenesis and bone repair in the setting of radiation therapy coupled with…”
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Stem Cells Rejuvenate Radiation-Impaired Vasculogenesis in Murine Distraction Osteogenesis by Deshpande, Sagar S., Gallagher, Kathleen K., Donneys, Alexis, Nelson, Noah S., Guys, Nicholas P., Felice, Peter A., Page, Erin E., Sun, Hongli, Krebsbach, Paul H., Buchman, Steven R.

“…BACKGROUND:Radiotherapy is known to be detrimental to bone and soft-tissue repair. Bone marrow stromal cells have been shown to enhance bone regeneration…”
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Deferoxamine expedites consolidation during mandibular distraction osteogenesis by Donneys, Alexis, Deshpande, Sagar S, Tchanque-Fossuo, Catherine N, Johnson, Kelsey L, Blough, Jordan T, Perosky, Joseph E, Kozloff, Kenneth M, Felice, Peter A, Nelson, Noah S, Farberg, Aaron S, Levi, Benjamin, Buchman, Steven R

“…Abstract Background A limitation of mandibular distraction osteogenesis (DO) is the length of time required for consolidation. This drawback subjects patients…”
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Identifying Risk Factors Leading to Unanticipated Postoperative Readmission by Felice, Peter A, Kerekes, David T, Mast, Bruce A

“…Unanticipated postoperative readmissions are a grading metric directly linked to both the quality of patient care and physician reimbursement. However, little…”
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Amifostine Reduces Radiation-Induced Complications in a Murine Model of Expander-Based Breast Reconstruction by Felice, Peter A., Nelson, Noah S., Page, Erin E., Deshpande, Sagar S., Donneys, Alexis, Rodriguez, José, Buchman, Steven R.

“…Immediate expander-based breast reconstruction after mastectomy is a prevalent option for many women with breast cancer. When coupled with adjuvant radiation…”
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Targeting angiogenesis as a therapeutic means to reinforce osteocyte survival and prevent nonunions in the aftermath of radiotherapy by Donneys, Alexis, Nelson, Noah S., Page, Erin E., Deshpande, Sagar S., Felice, Peter A., Tchanque-Fossuo, Catherine N., Spiegel, Joshua P., Buchman, Steven R.

“…Background Radiotherapy (XRT) exerts detrimental collateral effects on bone tissue through mechanisms of vascular damage and impediments to osteocytes,…”
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Translational treatment paradigm for managing non-unions secondary to radiation injury utilizing adipose derived stem cells and angiogenic therapy by Donneys, Alexis, Blough, Jordan T., Nelson, Noah S., Perosky, Joseph E., Deshpande, Sagar S., Kang, Stephen Y., Felice, Peter A., Figueredo, Christian, Peterson, Jonathan R., Kozloff, Kenneth M., Levi, Benjamin, Chepeha, Douglas B., Buchman, Steven R.

“…Background Bony non‐unions arising in the aftermath of collateral radiation injury are commonly managed with vascularized free tissue transfers. Unfortunately,…”
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Prophylactic Amifostine Preserves the Biomechanical Properties of Irradiated Bone in the Murine Mandible by Felice, Peter A., Ahsan, Salman, Perosky, Joseph E., Deshpande, Sagar S., Nelson, Noah S., Donneys, Alexis, Kozloff, Kenneth M., Buchman, Steven R.

“…The authors have previously demonstrated that amifostine prophylaxis mitigates the pernicious effects of radiation in settings of fracture repair and…”
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Significant Differences in the Bone of an Isogenic Inbred Versus Nonisogenic Outbred Murine Mandible: A Study in Rigor and Reproducibility by Carey, Edward G, Deshpande, Sagar S, Urlaub, Kevin M, Zheutlin, Alexander R, Nelson, Noah S, Donneys, Alexis, Kang, Stephen Y, Gallagher, Kathleen K, Felice, Peter A, Tchanque-Fossuo, Catherine N, Buchman, Steven R

“…Inattention to differences between animal strains is a potential cause of irreproducibility of basic science investigations. Accordingly, the authors'…”
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Prophylactic administration of Amifostine protects vessel thickness in the setting of irradiated bone by Page, Erin E, Deshpande, Sagar S, Nelson, Noah S, Felice, Peter A, Donneys, Alexis, Rodriguez, Jose J, Deshpande, Samir S, Buchman, Steven R

“…Summary Although often beneficial in the treatment of head and neck cancer (HNC), radiation therapy (XRT) leads to the depletion of vascular supply and…”
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Vascular analysis as a proxy for mechanostransduction response in an isogenic, irradiated murine model of mandibular distraction osteogenesis by Deshpande, Sagar S., Donneys, Alexis, Kang, Stephen Y., Page, Erin E., Felice, Peter A., Kiryakoza, Lauren, Nelson, Noah S., Rodriguez, Jose, Deshpande, Samir S., Buchman, Steven R.

“…Head and neck cancer is a debilitating and disfiguring disease. Although numerous treatment options exist, an array of debilitating side effects accompany…”
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Prophylactic administration of amifostine protects vessel thickness and luminal diameter in the setting of irradiation by Page, Erin E., BS, Deshpande, Sagar S., BS, Nelson, Noah S, Felice, Peter A., MD, Donneys, Alexis, MD, MS, Rodriguez, Jose J, Deshpande, Samir S, Buchman, Steven R., MD

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Amifostine prophylaxis preserves biomechanical properties of irradiated bone: A murine mandibular model by Felice, Peter A., MD, Donneys, Alexis, MD, MS, Deshpande, Sagar S., BS, Tchanque-Fossuo, Catherine N., MD, MS, Nelson, Noah S., BS, Sarhaddi, Deniz, BS, Perosky, Joseph E., MS, Kozloff, Kenneth M., PhD, Buchman, Steven R., MD, FACS

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Novel bacterial immobilization compound effectively decreases bacterial counts in healthy volunteers by Pabon, Diego F, Yost, Michael J, Melendez, Giselle C, Durand, Tamsin M, Brock, Timothy Z, Felice, Peter A, Campbell, Katherine, Bynoe, Raymond P, Fann, Stephen A

“…Skin flora immobilization technology is similar in efficacy to Iodine-Povidone in healthy volunteers. We did a prospective study in a university clinic with 60…”
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Abstract 101: Amifostine Prophylaxis Ameliorates Radiation-induced Injury in A Murine Model of Expander-based Breast Reconstruction by Polyatskaya, Yekaterina, Nelson, Noah S., Rodriguez, Jose J., Zheutlin, Alexander R., Deshpande, Sagar S., Felice, Peter A., Donneys, Alexis, Buchman, Steven R.

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