Search Results - "Felgueiras, Juliana"

Prostate cancer： the need for biomarkers and new therapeutic targets by Felgueiras, Juliana, Silva, Joana Vieira, Fardilha, Margarida

“…Prostate cancer （PCa） incidence and mortality have decreased in recent years. Nonetheless, it remains one of the most prevalent cancers in men, being a…”
Get full text

Protein phosphatase 1 in tumorigenesis: is it worth a closer look? by Felgueiras, Juliana, Jerónimo, Carmen, Fardilha, Margarida

“…Cancer cells take advantage of signaling cascades to meet their requirements for sustained growth and survival. Cell signaling is tightly controlled by…”
Get full text

Adding biological meaning to human protein-protein interactions identified by yeast two-hybrid screenings: A guide through bioinformatics tools by Felgueiras, Juliana, Silva, Joana Vieira, Fardilha, Margarida

“…“A man is known by the company he keeps” is a popular expression that perfectly fits proteins. A common approach to characterize the function of a target…”
Get full text

PP1 catalytic isoforms are differentially expressed and regulated in human prostate cancer by Felgueiras, Juliana, Lobo, João, Camilo, Vânia, Carneiro, Isa, Matos, Bárbara, Henrique, Rui, Jerónimo, Carmen, Fardilha, Margarida

“…The Ser/Thr-protein phosphatase PP1 (PP1) is a positive regulator of the androgen receptor (AR), which suggests major roles for PP1 in prostate carcinogenesis…”
Get full text

Signaling pathways in anchoring junctions of epithelial cells: cell-to-cell and cell-to-extracellular matrix interactions by Ferreira, Ana Rita, Felgueiras, Juliana, Fardilha, Margarida

“…Abstract Epithelial cells form the epithelium, one of the basic tissues of the human body. These cells present specializations from tissue to tissue,…”
Get full text

Investigation of spectroscopic and proteomic alterations underlying prostate carcinogenesis by Felgueiras, Juliana, Silva, Joana Vieira, Nunes, Alexandra, Fernandes, Inês, Patrício, António, Maia, Nuno, Pelech, Steven, Fardilha, Margarida

“…Prostate cancer (PCa) treatment remains challenging, especially in advanced stages, where the lack of sensitivity and specificity of available biomarkers makes…”
Get full text

An efficient synthetic access to new uracil-alditols bearing a porphyrin unit and biological assessment in prostate cancer cells by Dias, Cristina J., Sardo, Inês, Moura, Nuno M.M., Felgueiras, Juliana, Neves, M. Graça P.M.S., Fardilha, Margarida, Faustino, M. Amparo F.

“…An efficient access to porphyrin derivatives bearing uracil-alditol moieties at the β-pyrrolic position was developed. The synthetic strategy involved a hetero…”
Get full text

MP90-18 SIGNALING PATHWAYS IN HUMAN PROSTATE CARCINOGENESIS: DIFFERENTIAL PROTEIN EXPRESSION PATTERNS BETWEEN NORMAL AND CANCER TISSUES by Patricio, Antonio, Silva, Joana, Felgueiras, Juliana, Pelech, Steven, Maia, Nuno, Almeida, Saul, Lourenço, Joao, Fardilha, Margarida

Get full text

The power of the yeast two-hybrid system in the identification of novel drug targets: building and modulating PPP1 interactomes by Silva, Joana Vieira, Freitas, Maria João, Felgueiras, Juliana, Fardilha, Margarida

“…Since the description of the yeast two-hybrid (Y2H) method, it has become more and more evident that it is the most commonly used method to identify…”
Get more information

TGF‐β cascade regulation by PPP1 and its interactors –impact on prostate cancer development and therapy by Korrodi‐Gregório, Luís, Silva, Joana Vieira, Santos‐Sousa, Luís, Freitas, Maria João, Felgueiras, Juliana, Fardilha, Margarida

“…Protein phosphorylation is a key mechanism by which normal and cancer cells regulate their main transduction pathways. Protein kinases and phosphatases are…”
Get full text

Lipid remodelling in human melanoma cells in response to UVA exposure by Maciel, Elisabete, Felgueiras, Juliana, Silva, Eduarda M P, Ricardo, Fernando, Moreira, Ana S P, Melo, Tânia, Campos, Ana, Fardilha, Margarida, Domingues, Pedro, Domingues, M Rosário

“…Extensive exposure to UVA is thought to increase the risk of malignancy and the progression of melanoma, the most serious type of skin cancer. It is well known…”
Get more information

A ruthenium(II)-trithiacyclononane curcuminate complex: Synthesis, characterization, DNA-interaction, and cytotoxic activity by Henriques, Magda Carvalho, Faustino, Maria Amparo F., Silva, Artur M. S., Felgueiras, Juliana, Fardilha, Margarida, Braga, Susana Santos

“…The coordination of ruthenium(II) complexes to anionic oxygen-based donors are very rare. This study describes a simple, one-pot method for obtaining…”
Get full text

TGF ‐β cascade regulation by PPP 1 and its interactors –impact on prostate cancer development and therapy by Korrodi‐Gregório, Luís, Silva, Joana Vieira, Santos‐Sousa, Luís, Freitas, Maria João, Felgueiras, Juliana, Fardilha, Margarida

“…Protein phosphorylation is a key mechanism by which normal and cancer cells regulate their main transduction pathways. Protein kinases and phosphatases are…”
Get full text

O Papel do Complexo TCTEX1D4/ppp1 na Proliferação e Migração Celular by Felgueiras, Juliana Carina Cardoso

“…O cancro da próstata é um dos cancros mais prevalentes e incidentes em homens, sendo uma preocupante causa de morte a nível mundial. A ampla utilização do…”
Get full text