Search Results - "Felemban, Majed"

Cellular regeneration strategies for macular degeneration: past, present and future by Chichagova, Valeria, Hallam, Dean, Collin, Joseph, Zerti, Darin, Dorgau, Birthe, Felemban, Majed, Lako, Majlinda, Steel, David H.

“…Despite considerable effort and significant therapeutic advances, age-related macular degeneration (AMD) remains the commonest cause of blindness in the…”
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Systematic Comparison of Retinal Organoid Differentiation from Human Pluripotent Stem Cells Reveals Stage Specific, Cell Line, and Methodological Differences by Mellough, Carla B., Collin, Joseph, Queen, Rachel, Hilgen, Gerrit, Dorgau, Birthe, Zerti, Darin, Felemban, Majed, White, Kathryn, Sernagor, Evelyne, Lako, Majlinda

“…A major goal in the stem cell field is to generate tissues that can be utilized as a universal tool for in vitro models of development and disease, drug…”
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Extracellular matrix component expression in human pluripotent stem cell-derived retinal organoids recapitulates retinogenesis in vivo and reveals an important role for IMPG1 and CD44 in the development of photoreceptors and interphotoreceptor matrix by Felemban, Majed, Dorgau, Birthe, Hunt, Nicola Claire, Hallam, Dean, Zerti, Darin, Bauer, Roman, Ding, Yuchun, Collin, Joseph, Steel, David, Krasnogor, Natalio, Al-Aama, Jumana, Lindsay, Susan, Mellough, Carla, Lako, Majlinda

“…[Display omitted] The extracellular matrix (ECM) plays an important role in numerous processes including cellular proliferation, differentiation, migration,…”
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Utilization of a nanostructured lipid carrier encapsulating pitavastatin-Pinus densiflora oil for enhancing cytotoxicity against the gingival carcinoma HGF-1 cell line by Felimban, Raed I., Tayeb, Hossam H., Chaudhary, Adeel G, Felemban, Majed A., Alnadwi, Fuad H., Ali, Sarah A., Alblowi, Jazia A., ALfayez, Eman, Bukhary, Deena, Alissa, Mohammed, Qahl, Safa H.

“…Oral squamous cell carcinoma (OSCC) is the most common epithelial tumor of the oral cavity. Gingival tumors, a unique type of OSCC, account for 10% of these…”
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Differentiation of Retinal Organoids from Human Pluripotent Stem Cells by Chichagova, Valeria, Dorgau, Birthe, Felemban, Majed, Georgiou, Maria, Armstrong, Lyle, Lako, Majlinda

“…This unit describes a protocol for generating retinal organoids that contain all major retinal cell types and are responsive to light from human pluripotent…”
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Design and Development of Neomycin Sulfate Gel Loaded with Solid Lipid Nanoparticles for Buccal Mucosal Wound Healing by Hosny, Khaled M., Naveen, N. Raghavendra, Kurakula, Mallesh, Sindi, Amal M., Sabei, Fahad Y., Fatease, Adel Al, Jali, Abdulmajeed M., Alharbi, Waleed S., Mushtaq, Rayan Y., Felemban, Majed, Tayeb, Hossam H., Alfayez, Eman, Rizg, Waleed Y.

“…Drug administration to the wound site is a potential method for wound healing. The drug retention duration should be extended, and drug permeability through…”
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A transcriptomic signature of X chromosome overdosage in Saudi Klinefelter syndrome induced pluripotent stem cells by Astro, Veronica, Fiacco, Elisabetta, Cardona-Londoño, Kelly Johanna, De Toma, Ilario, Alzahrani, Hams Saeed, Alama, Jumana, Kokandi, Amal, Hamoda, Taha Abo-Almagd Abdel-Meguid, Felemban, Majed, Adamo, Antonio

“…The transcriptional landscape of Klinefelter syndromeduring early embryogenesis remains elusive. This study aimed to evaluate the impact of X chromosome…”
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Developing a simple method to enhance the generation of cone and rod photoreceptors in pluripotent stem cell‐derived retinal organoids by Zerti, Darin, Dorgau, Birthe, Felemban, Majed, Ghareeb, Ali E., Yu, Min, Ding, Yuchun, Krasnogor, Natalio, Lako, Majlinda

“…Cell replacement therapy is a promising treatment for irreversible retinal cell death in diverse diseases such as Stargardt's disease, age‐related macular…”
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Decellularised extracellular matrix-derived peptides from neural retina and retinal pigment epithelium enhance the expression of synaptic markers and light responsiveness of human pluripotent stem cell derived retinal organoids by Dorgau, Birthe, Felemban, Majed, Hilgen, Gerrit, Kiening, Martin, Zerti, Darin, Hunt, Nicola Claire, Doherty, Mary, Whitfield, Phil, Hallam, Dean, White, Kathryn, Ding, Yuchun, Krasnogor, Natalio, Al-Aama, Jumana, Asfour, Hani Z., Sernagor, Evelyne, Lako, Majlinda

“…Tissue specific extracellular matrices (ECM) provide structural support and enable access to molecular signals and metabolites, which are essential for…”
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Laminin γ3 plays an important role in retinal lamination, photoreceptor organisation and ganglion cell differentiation by Dorgau, Birthe, Felemban, Majed, Sharpe, Alexander, Bauer, Roman, Hallam, Dean, Steel, David H., Lindsay, Susan, Mellough, Carla, Lako, Majlinda

“…Laminins are heterotrimeric glycoproteins of the extracellular matrix. Eleven different laminin chains have been identified in vertebrates. They are…”
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Investigating the role of the extracellular matrix (ECM) on pluripotent stem cell differentiation towards retinal lineages by Felemban, Majed Abdulsamad A

“…Human pluripotent stem cells (hPSCs) can be differentiated into retinal organoids to study inherited and age related retinal dystrophies, to screen new drugs…”
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