Search Results - "Feldon, Steven E."

TNF-α and NF-κB signaling play a critical role in cigarette smoke-induced epithelial-mesenchymal transition of retinal pigment epithelial cells in proliferative vitreoretinopathy by Wang, Victor, Heffer, Alison, Roztocil, Elisa, Feldon, Steven E, Libby, Richard T, Woeller, Collynn F, Kuriyan, Ajay E

“…Proliferative vitreoretinopathy (PVR) is characterized by the growth and contraction of cellular membranes within the vitreous cavity and on both surfaces of…”
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The aryl hydrocarbon receptor pathway controls matrix metalloproteinase-1 and collagen levels in human orbital fibroblasts by Roztocil, Elisa, Hammond, Christine L., Gonzalez, Mithra O., Feldon, Steven E., Woeller, Collynn F.

“…Thyroid eye disease (TED) affects 25–50% of patients with Graves’ Disease. In TED, collagen accumulation leads to an expansion of the extracellular matrix…”
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Proton pump inhibitors attenuate myofibroblast formation associated with thyroid eye disease through the aryl hydrocarbon receptor by Hammond, Christine L, Roztocil, Elisa, Phipps, Richard P, Feldon, Steven E, Woeller, Collynn F

“…Thyroid eye disease (TED) can lead to scar formation and tissue remodeling in the orbital space. In severe cases, the scarring process leads to…”
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Salinomycin inhibits proliferative vitreoretinopathy formation in a mouse model by Heffer, Alison M, Wang, Victor, Libby, Richard T, Feldon, Steven E, Woeller, Collynn F, Kuriyan, Ajay E

“…Proliferative vitreoretinopathy (PVR) is a progressive disease that develops in a subset of patients who undergo surgery for retinal detachment repair, and…”
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Salinomycin and Other Polyether Ionophores Are a New Class of Antiscarring Agent by Woeller, Collynn F., O'Loughlin, Charles W., Roztocil, Elisa, Feldon, Steven E., Phipps, Richard P.

“…Although scarring is a component of wound healing, excessive scar formation is a debilitating condition that results in pain, loss of tissue function, and even…”
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The polyether ionophore salinomycin targets multiple cellular pathways to block proliferative vitreoretinopathy pathology by Heffer, Alison M, Proaño, Jacob, Roztocil, Elisa, Phipps, Richard P, Feldon, Steven E, Huxlin, Krystel R, Sime, Patricia J, Libby, Richard T, Woeller, Collynn F, Kuriyan, Ajay E

“…Proliferative vitreoretinopathy (PVR) is characterized by membranes that form in the vitreous cavity and on both surfaces of the retina, which results in the…”
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The Effect of Treatment of Idiopathic Intracranial Hypertension on Prevalence of Retinal and Choroidal Folds by Kupersmith, Mark J., MD, Sibony, Patrick A., MD, Feldon, Steven E., MD, MBA, Wang, Jui-Kai, MS, Garvin, Mona, PhD, Kardon, Randy, MD, PhD

“…Abstract Purpose We described 3 types of folds in the retina and a crease in the outer retina associated with papilledema due to idiopathic intracranial…”
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Orbital fibroblasts from thyroid eye disease patients differ in proliferative and adipogenic responses depending on disease subtype by Kuriyan, Ajay E, Woeller, Collynn F, O'Loughlin, Charles W, Phipps, Richard P, Feldon, Steven E

“…Thyroid eye disease (TED) patients are classified as type I (predominantly fat compartment enlargement) or type II (predominantly extraocular muscle…”
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Vision‐related quality of life after unilateral occipital stroke by Dogra, Neil, Redmond, Bryan V., Lilley, Selena, Johnson, Brent A., Lam, Byron L., Tamhankar, Madhura, Feldon, Steven E., Fahrenthold, Berkeley, Yang, Jingyi, Huxlin, Krystel R., Cavanaugh, Matthew R.

“…Background/objectives Stroke damage to the primary visual cortex induces large, homonymous visual field defects that impair daily living. Here, we asked if…”
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More than Meets the Eye: The Aryl Hydrocarbon Receptor is an Environmental Sensor, Physiological Regulator and a Therapeutic Target in Ocular Disease by Hammond, Christine L, Roztocil, Elisa, Gupta, Vardaan, Feldon, Steven E, Woeller, Collynn F

“…The aryl hydrocarbon receptor (AHR) is a ligand activated transcription factor originally identified as an environmental sensor of xenobiotic chemicals…”
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The Aryl Hydrocarbon Receptor and Its Ligands Inhibit Myofibroblast Formation and Activation by Woeller, Collynn F, Roztocil, Elisa, Hammond, Christine L, Feldon, Steven E, Phipps, Richard P

“…Thyroid eye disease (TED) is a degenerative disease that manifests with detrimental tissue remodeling, myofibroblast accumulation, and scarring in the orbit of…”
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The Aryl Hydrocarbon Receptor Ligand ITE Inhibits TGFβ1-Induced Human Myofibroblast Differentiation by Lehmann, Geniece M, Xi, Xia, Kulkarni, Ajit A, Olsen, Keith C, Pollock, Stephen J, Baglole, Carolyn J, Gupta, Shikha, Casey, Ann E, Huxlin, Krystel R, Sime, Patricia J, Feldon, Steven E, Phipps, Richard P

“…Fibrosis can occur in any human tissue when the normal wound healing response is amplified. Such amplification results in fibroblast proliferation,…”
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Late Onset Optic Neuropathy in Methylmalonic and Propionic Acidemia by Williams, Zoë R, Hurley, P. Emmett, Altiparmak, Ugur E, Feldon, Steven E, Arnold, Georgianne L, Eggenberger, Eric, Mejico, Luis J

“…Purpose To describe 3 cases of late-onset bilateral optic neuropathy with visual dysfunction in patients with organic acidemia. Design Retrospective case…”
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TSHR Signaling Stimulates Proliferation Through PI3K/Akt and Induction of miR-146a and miR-155 in Thyroid Eye Disease Orbital Fibroblasts by Woeller, Collynn F, Roztocil, Elisa, Hammond, Christine, Feldon, Steven E

“…To investigate the molecular pathways that drive thyroid stimulating hormone receptor (TSHR)-induced cellular proliferation in orbital fibroblasts (OFs) from…”
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Effect of Acetazolamide on Visual Function in Patients With Idiopathic Intracranial Hypertension and Mild Visual Loss: The Idiopathic Intracranial Hypertension Treatment Trial by Wall, Michael, McDermott, Michael P, Kieburtz, Karl D, Corbett, James J, Feldon, Steven E, Friedman, Deborah I, Katz, David M, Keltner, John L, Schron, Eleanor B, Kupersmith, Mark J

“…IMPORTANCE Acetazolamide is commonly used to treat idiopathic intracranial hypertension (IIH), but there is insufficient information to establish an evidence…”
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The idiopathic intracranial hypertension treatment trial: clinical profile at baseline by Wall, Michael, Kupersmith, Mark J, Kieburtz, Karl D, Corbett, James J, Feldon, Steven E, Friedman, Deborah I, Katz, David M, Keltner, John L, Schron, Eleanor B, McDermott, Michael P

“…To our knowledge, there are no large prospective cohorts of untreated patients with idiopathic intracranial hypertension (IIH) to characterize the disease. To…”
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Tapinarof, an Aryl Hydrocarbon Receptor Ligand, Mitigates Fibroblast Activation in Thyroid Eye Disease: Implications for Novel Therapy by Patrick, Charkira C., Roztocil, Elisa, Husain, Farha, Feldon, Steven E., Woeller, Collynn F.

“…In thyroid eye disease (TED), activation and proliferation of orbital fibroblasts (OFs) promotes remodeling and causes an increase in the volume of orbital…”
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Rehabilitation of cortically induced visual field loss by Saionz, Elizabeth L., Feldon, Steven E., Huxlin, Krystel R.

“…Homonymous visual field defects are a common sequela of stroke, and are assumed to be permanent within a few weeks of the event. Because consensus about the…”
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MicroRNA-130a Is Elevated in Thyroid Eye Disease and Increases Lipid Accumulation in Fibroblasts Through the Suppression of AMPK by Hammond, Christine L, Roztocil, Elisa, Gonzalez, Mithra O, Feldon, Steven E, Woeller, Collynn F

“…Thyroid eye disease (TED) is a condition that causes the tissue behind the eye to become inflamed and can result in excessive fatty tissue accumulation in the…”
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Efficacy of Visual Retraining in the Hemianopic Field after Stroke: Results of a Randomized Clinical Trial by Cavanaugh, Matthew R, Blanchard, Lisa M, McDermott, Michael, Lam, Byron L, Tamhankar, Madhura, Feldon, Steven E

“…To evaluate the efficacy of motion discrimination training as a potential therapy for stroke-induced hemianopic visual field defects. Clinical trial…”
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