Search Results - "Feldmann, G"

Surface expression and cytolytic function of natural killer cell receptors is altered in chronic hepatitis C by Nattermann, J, Feldmann, G, Ahlenstiel, G, Langhans, B, Sauerbruch, T, Spengler, U

“…Introduction: Impaired activity of natural killer (NK) cells has been proposed as a mechanism contributing to viral persistence in hepatitis C virus (HCV)…”
Get full text

Hedgehog inhibition prolongs survival in a genetically engineered mouse model of pancreatic cancer by Feldmann, G, Habbe, N, Dhara, S, Bisht, S, Alvarez, H, Fendrich, V, Beaty, R, Mullendore, M, Karikari, C, Bardeesy, N, Ouellette, M M, Yu, W, Maitra, A

“…Pancreatic cancer is among the most dismal of human malignancies. Current therapeutic strategies are virtually ineffective in controlling advanced, metastatic…”
Get more information

The Yes-associated protein controls the cell density regulation of Hedgehog signaling by Tariki, M, Dhanyamraju, P K, Fendrich, V, Borggrefe, T, Feldmann, G, Lauth, M

“…The evolutionarily conserved Hedgehog (Hh) signaling pathway is essential for correct embryogenesis and is misregulated in several malignancies. In cell…”
Get full text

A Step-by-Step Clinical Approach for the Management of Neuroendocrine Tumours by Yordanova, A, Ahmadzadehfar, H, Gonzalez-Carmona, M, Strassburg, C, Mayer, K, Feldmann, G, Schmidt-Wolf, I, Lingohr, P, Fischer, S, Kristiansen, G, Essler, M

“…Neuroendocrine tumours (NET) are rare neoplasms, but the incidence is permanently increasing. Most of the NETs are slow proliferating and clinically silent,…”
Get more information

Expression of the zinc-finger transcription factor Snail in adrenocortical carcinoma is associated with decreased survival by Waldmann, J, Feldmann, G, Slater, E P, Langer, P, Buchholz, M, Ramaswamy, A, Saeger, W, Rothmund, M, Fendrich, V

“…In this study, we evaluate whether Snail is expressed in adrenocortical cancer (ACC) and if its expression is related to patient outcome. One of the best known…”
Get full text

Activated gamma delta T cells express the natural cytotoxicity receptor natural killer p44 and show cytotoxic activity against myeloma cells by von Lilienfeld-Toal, M, Nattermann, J, Feldmann, G, Sievers, E, Frank, S, Strehl, J, Schmidt-Wolf, IGH

“…gamma delta T cells account for up to 10% of T lymphocytes in the peripheral blood of healthy donors. They can be activated by cytokines such as interleukin…”
Get full text

Activated γδ T cells express the natural cytotoxicity receptor natural killer p44 and show cytotoxic activity against myeloma cells by Von Lilienfeld‐Toal, M., Nattermann, J., Feldmann, G., Sievers, E., Frank, S., Strehl, J., Schmidt‐Wolf, I. G. H.

“…Summary γδ T cells account for up to 10% of T lymphocytes in the peripheral blood of healthy donors. They can be activated by cytokines such as interleukin…”
Get full text

Cadmium induces mitochondria-dependent apoptosis of normal human hepatocytes by Lasfer, M., Vadrot, N., Aoudjehane, L., Conti, F., Bringuier, A. F., Feldmann, G., Reyl-Desmars, F.

“…The heavy metal cadmium, an environmental pollutant, has been widely demonstrated to be toxic, in particular for liver. In murines, cadmium induces apoptosis…”
Get full text

Steatohepatitis-inducing drugs cause mitochondrial dysfunction and lipid peroxidation in rat hepatocytes by Berson, Alain, De Beco, Virginie, Lettéron, Philippe, Robin, Marie Anne, Moreau, Claire, Kahwaji, Johny El, Verthier, Nicole, Feldmann, Gérard, Fromenty, Bernard, Pessayre, Dominique

“…Background & Aims: 4,4'-Diethylaminoethoxyhexestrol (DEAEH), amiodarone, and perhexiline cause steatohepatitis in humans. The mechanisms of these effects are…”
Get full text

Liver transplantation of hepatic stem cells: potential use for treating liver diseases by Feldmann, G

“…Hepatic stem cells are an alternative means for repopulating the liver after various injuries instead of liver transplantation. The first step before use is to…”
Get full text

Intrinsic cardiomyopathy in pediatric Marfan syndrome: predictive factors and risk assessments by Kneußel, Jonas, Olfe, Jakob, Stark, Veronika C, von Kodolitsch, Yskert, Kozlik-Feldmann, Rainer G, Friehs, Ingeborg, Kutsche, Kerstin, Hübler, Michael, Mir, Thomas S, Diaz-Gil, Daniel

“…Marfan syndrome (MFS) is associated with cardiovascular complications, particularly valvulopathies; however, its association with primary cardiomyopathy…”
Get full text

An alcoholic binge causes massive degradation of hepatic mitochondrial DNA in mice by Mansouri, Abdellah, Gaou, Isabelle, de Kerguenec, Caroline, Amsellem, Sabine, Haouzi, Delphine, Berson, Alain, Moreau ‡, Alain, Feldmann ‡, Gérard, Lettéron, Philippe, Pessayre, Dominique, Fromenty, Bernard

“…Background & Aims: Ethanol causes oxidative stress in the hepatic mitochondria of experimental animals and mitochondrial DNA deletions in alcoholics. We…”
Get full text

Pulmonary hypertension in adults with congenital heart disease: Updated recommendations from the Cologne Consensus Conference 2018 by Kaemmerer, Harald, Apitz, Christian, Brockmeier, Konrad, Eicken, Andreas, Gorenflo, Matthias, Hager, Alfred, de Haan, Fokko, Huntgeburth, Michael, Kozlik-Feldmann, Rainer G., Miera, Oliver, Diller, Gerhard P.

“…In the summer of 2016, delegates from the German Respiratory Society (DGP), the German Society of Cardiology (DGK) and the German Society of Pediatric…”
Get full text

Critical analysis of the methods used to morphologically quantify hepatic fibrosis by FELDMANN, G

Get full text

Binding of HCV E2 to CD81 induces RANTES secretion and internalization of CC chemokine receptor 5 by Nattermann, J., Nischalke, H. D., Feldmann, G., Ahlenstiel, G., Sauerbruch, T., Spengler, U.

“…Hepatitis C virus (HCV) infection has been shown to be associated with reduced expression of the CC chemokine receptor (CCR) 5, and reduced responsiveness of…”
Get full text

Mechanisms for experimental buprenorphine hepatotoxicity: major role of mitochondrial dysfunction versus metabolic activation by Berson, Alain, Fau, Daniel, Fornacciari, Roxane, Degove-Goddard, Pamela, Sutton, Angela, Descatoire, Véronique, Haouzi, Delphine, Lettéron, Philippe, Moreau, Alain, Feldmann, Gérard, Pessayre, Dominique

“…Background/Aims : Although sublingual buprenorphine is safely used as a substitution drug in heroin addicts, large overdoses or intravenous misuse may cause…”
Get full text

Diterpenoids from germander, an herbal medicine, induce apoptosis in isolated rat hepatocytes by Fau, D, Lekehal, M, Farrell, G, Moreau, A, Moulis, C, Feldmann, G, Haouzi, D, Pessayre, D

“…BACKGROUND & AIMS: Germander was withdrawn from the market after its use for weight control caused an epidemic of hepatitis. Its toxicity was shown to be…”
Get full text

Hepatitis C virus detection in follicular fluid and culture media from HCV+ women, and viral risk during IVF procedures by Devaux, A., Soula, V., Sifer, C., Branger, M., Naouri, M., Porcher, R., Poncelet, C., Neuraz, A., Alvarez, S., Benifla, J.L., Madelenat, P., Brun‐Vezinet, F., Feldmann, G.

“…BACKGROUND: Hepatitis C virus (HCV) has been detected in sperm, but no data are available on follicular fluid (FF) collected on IVF procedures. The aim of this…”
Get full text

Expression of cadherins and CD44 isoforms in human endometrium and peritoneal endometriosis by Poncelet, Christophe, Leblanc, Marc, Walker-Combrouze, Francine, Soriano, David, Feldmann, Gérard, Madelenat, Patrick, Scoazec, Jean-Yves, Daraï, Emile

“…To evaluate (a) cadherins and CD44 expression in normal endometrium and in peritoneal endometriosis, and (b) to correlate, their expressions with…”
Get more information

640 IN VIVO LIVER ENDOPLASMIC RETICULUM STRESS IN CHRONIC HEPATITIS C by Asselah, T, Bièche, I, Mansouri, A, Laurendeau, I, Cazals-Hatem, D, Feldmann, G, Bedossa, P, Paradis, V, Martinot-Peignoux, M, Lebrec, D, Guichard, C, Ogier-Denis, E, Vidaud, M, Tellie, Z, Soumelis, V, Marcellin, P, Moreau, R

Get full text