Search Results - "Felber, BK"

A minimal T-cell immunogen designed to cover HIV-1 specificities associated with control is immunogenic in mice and breaks CTL immunodominance by Mothe, B, Llano, A, Rosati, M, Perez-Alvarez, S, Kulkarni, V, Chowdhury, B, Alicea, C, Beach, RK, Sardesai, NY, Pavlakis, GN, Felber, BK, Brander, C

“…Doc number: P305…”
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DNA vaccines expressing conserved elements provide potent and broad immune responses by Pavlakis, GN, Kulkarni, V, Valentin, A, Rosati, M, Sardesai, NY, Mothe, B, Brander, C, LeGall, S, Weiner, DB, Rolland, M, Mullins, JI, Felber, BK

“…Doc number: O67…”
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P18-09. Persistent virological benefit in SIV-infected macaques upon therapeutic vaccination upon vaccination with DNA vectors by Felber, BK, Valentin, A, von Gegerfelt, A, Jalah, R, Patel, V, Kulkarni, V, Alicea, C, Rosati, M, Khan, A, Draghia-Akli, R, Pavlakis, GN

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P11-19. Altered mucosal distribution of SIV-specific T cells in Rhesus macaques infected with the live-attenuated Rev-independent SIV by Valentin, A, von Gegerfelt, A, Alicea, C, Patel, V, Marthas, M L, Van Rompay, K, Pavlakis, G N, Felber, B K

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P14-08. Intramuscular DNA delivery by electroporation leads to greatly enhanced systemic and mucosal immune responses and control of SIVmac251 challenge by Pavlakis, GN, Rosati, M, Patel, V, Valentin, A, Bergamaschi, C, Kulkarni, V, Jalah, R, von Gegerfelt, A, Ohlen, C, Khan, A, Draghia-Akli, R, Van Rompay, K, Felber, BK

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OAO5-04. Gp96-Ig-SIV vaccines induce predominant immune responses at mucosal sites by Strbo, N, Vaccari, M, Pahwa, S, Kolber, MA, Fisher, E, Gonzalez, L, Felber, B K, Pavlakis, G N, Franchini, G, Podack, E R

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A Quantitative Bioassay for HIV-1 Based on Trans-Activation by Felber, Barbara K., Pavlakis, George N.

“…A bioassay that is based on trans-activation has been developed for the detection and quantitation of the human immunodeficiency virus type 1 (HIV-1)…”
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Coimmunization with an Optimized IL-15 Plasmid Results in Enhanced Function and Longevity of CD8 T Cells That Are Partially Independent of CD4 T Cell Help by Kutzler, Michele A, Robinson, Tara M, Chattergoon, Michael A, Choo, Daniel K, Choo, Andrew Y, Choe, Philip Y, Ramanathan, Mathura P, Parkinson, Rose, Kudchodkar, Sagar, Tamura, Yutaka, Sidhu, Maninder, Roopchand, Vidia, Kim, J. Joseph, Pavlakis, George N, Felber, Barbara K, Waldmann, Thomas A, Boyer, Jean D, Weiner, David B

“…DNA vaccines are a promising technology for the induction of Ag-specific immune responses, and much recent attention has gone into improving their immune…”
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TAP, the human homolog of Mex67p, mediates CTE-dependent RNA export from the nucleus by Grüter, P, Tabernero, C, von Kobbe, C, Schmitt, C, Saavedra, C, Bachi, A, Wilm, M, Felber, B K, Izaurralde, E

“…The constitutive transport element (CTE) of the type D retroviruses promotes nuclear export of unspliced viral RNAs apparently by recruiting host factor(s)…”
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Containment of Simian Immunodeficiency Virus Infection in Vaccinated Macaques: Correlation with the Magnitude of Virus-Specific Pre- and Postchallenge CD4+ and CD8+ T Cell Responses by Hel, Zdenek, Nacsa, Janos, Tryniszewska, Elzbieta, Tsai, Wen-Po, Parks, Robyn Washington, Montefiori, David C, Felber, Barbara K, Tartaglia, James, Pavlakis, George N, Franchini, Genoveffa

“…Macaques infected with the SIV strain SIVmac251 develop a disease closely resembling human AIDS characterized by high viremia, progressive loss of CD4(+) T…”
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DNA Vaccines Expressing Different Forms of Simian Immunodeficiency Virus Antigens Decrease Viremia upon SIVmac251 Challenge by ROSATI, Margherita, VON GEGERFELT, Agneta, PAVLAKIS, George N, ROTH, Patricia, ALICEA, Candido, VALENTIN, Antonio, ROBERT-GUROFF, Marjorie, VENZON, David, MONTEFIORI, David C, MARKHAM, Phil, FELBER, Barbara K

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PSF Acts through the Human Immunodeficiency Virus Type 1 mRNA Instability Elements To Regulate Virus Expression by Zolotukhin, Andrei S., Michalowski, Daniel, Bear, Jenifer, Smulevitch, Sergey V., Traish, Abdulmaged M., Peng, Rui, Patton, James, Shatsky, Ivan N., Felber, Barbara K.

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Improved Vaccine Protection from Simian AIDS by the Addition of Nonstructural Simian Immunodeficiency Virus Genes by Hel, Zdenek, Tsai, Wen-Po, Tryniszewska, Elzbieta, Nacsa, Janos, Markham, Phillip D, Lewis, Mark G, Pavlakis, George N, Felber, Barbara K, Tartaglia, Jim, Franchini, Genoveffa

“…An HIV-1 vaccine able to induce broad CD4+ and CD8+ T cell responses may provide long-term control of viral replication. In this study we directly assess the…”
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Nucleoporins Nup98 and Nup214 Participate in Nuclear Export of Human Immunodeficiency Virus Type 1 Rev by Zolotukhin, A S, Felber, B K

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Co-immunization with HIV Env DNA and protein elicit long-lasting strong cellular and humoral immune responses by Li, J, Valentin, A, Kulkarni, V, Alicea, C, Kelly Beach, R, Rosati, M, Jalah, R, Reed, S, Felber, BK, Pavlakis, GN

“…Doc number: P340…”
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Nuclear Export Factor Family Protein Participates in Cytoplasmic mRNA Trafficking by Tretyakova, Irina, Zolotukhin, Andrei S., Tan, Wei, Bear, Jenifer, Propst, Friedrich, Ruthel, Gordon, Felber, Barbara K.

“…In eukaryotes, the nuclear export of mRNA is mediated by nuclear export factor 1 (NXF1) receptors. Metazoans encode additional NXF1-related proteins of unknown…”
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Inactivation of the human immunodeficiency virus type 1 inhibitory elements allows Rev-independent expression of Gag and Gag/protease and particle formation by Schneider, R, Campbell, M, Nasioulas, G, Felber, B K, Pavlakis, G N

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The mRNA export in Caenorhabditis elegans is mediated by Ce-NXF-1, an ortholog of human TAP/NXF and Saccharomyces cerevisiae Mex67p by TAN, WEI, ZOLOTUKHIN, ANDREI S., BEAR, JENIFER, PATENAUDE, DANIEL J., FELBER, BARBARA K.

“…Human TAP and Saccharomyces cerevisiae Mex67p belong to a family of proteins that mediate mRNA export. Computer searches identified previously two…”
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Identification of Novel Import and Export Signals of Human TAP, the Protein That Binds to the Constitutive Transport Element of the Type D Retrovirus mRNAs by Bear, Jenifer, Tan, Wei, Zolotukhin, Andrei S., Tabernero, Carlos, Hudson, Eric A., Felber, Barbara K.

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Identification and characterization of the mouse nuclear export factor (Nxf) family members by Tan, Wei, Zolotukhin, Andrei S., Tretyakova, Irina, Bear, Jenifer, Lindtner, Susan, Smulevitch, Sergey V., Felber, Barbara K.

“…TAP/hNXF1 is a key factor that mediates general cellular mRNA export from the nucleus, and its orthologs are structurally and functionally conserved from yeast…”
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