Search Results - "Felau, Ina"

Abstract 5895: Whole-genome characterization of lung adenocarcinomas lacking alterations in RTK/RAS/RAF/MAPK pathway by Carrot-Zhang, Jian, Devarakonda, Siddhartha, Robine, Nicolas, Yao, Xiaotong, Silva, Tiago C., Damrauer, Jeff, Deshpande, Aditya, Tsao, Ming-Sound, Yao, Christina, Wong, Chris, Bao, Lisui, Choi, Hyo Young, Felau, Ina, Zenklusen, Jean C., Robertson, Gordon, Trieua, Tuan, Liang, Wei-Wei, Zhou, Meng, Rheinbay, Esther, Hayes, Neil, Khurana, Ekta, Ding, Li, Laird, Peter, Elemento, Olivier, Weinstein, John, Kwiatkowski, David, Benz, Chris, Stuart, Josh, Yang, Lixing, Castro, Mauro, Travis, William, Hoadley, Katherine, Berman, Ben, Meyerson, Matthew, Govindan, Ramaswamy, Imielinski, Marcin

“…Abstract Lung adenocarcinomas (LUAD) are typically characterized by genetic activation of the receptor tyrosine kinase (RTK)/RAS/RAF/MAP kinase (MAPK) pathway…”
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Comprehensive Analysis of Genetic Ancestry and Its Molecular Correlates in Cancer by Carrot-Zhang, Jian, Chambwe, Nyasha, Damrauer, Jeffrey S., Knijnenburg, Theo A., Robertson, A. Gordon, Yau, Christina, Zhou, Wanding, Berger, Ashton C., Huang, Kuan-lin, Newberg, Justin Y., Mashl, R. Jay, Romanel, Alessandro, Sayaman, Rosalyn W., Demichelis, Francesca, Felau, Ina, Frampton, Garrett M., Han, Seunghun, Hoadley, Katherine A., Kemal, Anab, Laird, Peter W., Lazar, Alexander J., Le, Xiuning, Oak, Ninad, Shen, Hui, Wong, Christopher K., Zenklusen, Jean C., Ziv, Elad, Aguet, Francois, Ding, Li, Demchok, John A., Mensah, Michael K.A., Caesar-Johnson, Samantha, Tarnuzzer, Roy, Wang, Zhining, Yang, Liming, Alfoldi, Jessica, Karczewski, Konrad J., MacArthur, Daniel G., Meyerson, Matthew, Benz, Christopher, Stuart, Joshua M., Cherniack, Andrew D., Beroukhim, Rameen

“…We evaluated ancestry effects on mutation rates, DNA methylation, and mRNA and miRNA expression among 10,678 patients across 33 cancer types from The Cancer…”
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Comprehensive Molecular Characterization of the Hippo Signaling Pathway in Cancer by Wang, Yumeng, Xu, Xiaoyan, Maglic, Dejan, Dill, Michael T, Mojumdar, Kamalika, Ng, Patrick Kwok-Shing, Jeong, Kang Jin, Tsang, Yiu Huen, Moreno, Daniela, Bhavana, Venkata Hemanjani, Peng, Xinxin, Ge, Zhongqi, Chen, Hu, Li, Jun, Chen, Zhongyuan, Zhang, Huiwen, Han, Leng, Du, Di, Creighton, Chad J, Mills, Gordon B, Camargo, Fernando, Liang, Han

“…Hippo signaling has been recognized as a key tumor suppressor pathway. Here, we perform a comprehensive molecular characterization of 19 Hippo core genes in…”
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Molecular analysis of thymic epithelial tumors (TETs): A report by The Cancer Genome Atlas (TCGA) research network by Loehrer, Patrick J., Tsao, Anne S., Radovich, Milan, Felau, Ina

“…Abstract only 8520 Background: Thymoma (T) and thymic carcinoma (TC) are the most common malignancies of the anterior mediastinum. Additionally, thymoma has an…”
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Integrative Analysis Identifies Four Molecular and Clinical Subsets in Uveal Melanoma by Robertson, A. Gordon, Shih, Juliann, Yau, Christina, Gibb, Ewan A., Oba, Junna, Mungall, Karen L., Hess, Julian M., Uzunangelov, Vladislav, Walter, Vonn, Danilova, Ludmila, Lichtenberg, Tara M., Kucherlapati, Melanie, Kimes, Patrick K., Tang, Ming, Penson, Alexander, Babur, Ozgun, Akbani, Rehan, Bristow, Christopher A., Hoadley, Katherine A., Iype, Lisa, Chang, Matthew T., Cherniack, Andrew D., Benz, Christopher, Mills, Gordon B., Verhaak, Roel G.W., Griewank, Klaus G., Felau, Ina, Zenklusen, Jean C., Gershenwald, Jeffrey E., Schoenfield, Lynn, Lazar, Alexander J., Abdel-Rahman, Mohamed H., Roman-Roman, Sergio, Stern, Marc-Henri, Cebulla, Colleen M., Williams, Michelle D., Jager, Martine J., Coupland, Sarah E., Esmaeli, Bita, Kandoth, Cyriac, Woodman, Scott E.

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Before and After: Comparison of Legacy and Harmonized TCGA Genomic Data Commons' Data by Gao, Galen F, Parker, Joel S, Reynolds, Sheila M, Silva, Tiago C, Wang, Liang-Bo, Zhou, Wanding, Akbani, Rehan, Bailey, Matthew, Balu, Saianand, Berman, Benjamin P, Brooks, Denise, Chen, Hu, Cherniack, Andrew D, Demchok, John A, Ding, Li, Felau, Ina, Gaheen, Sharon, Gerhard, Daniela S, Heiman, David I, Hernandez, Kyle M, Hoadley, Katherine A, Jayasinghe, Reyka, Kemal, Anab, Knijnenburg, Theo A, Laird, Peter W, Mensah, Michael K A, Mungall, Andrew J, Robertson, A Gordon, Shen, Hui, Tarnuzzer, Roy, Wang, Zhining, Wyczalkowski, Matthew, Yang, Liming, Zenklusen, Jean C, Zhang, Zhenyu, Liang, Han, Noble, Michael S

“…We present a systematic analysis of the effects of synchronizing a large-scale, deeply characterized, multi-omic dataset to the current human reference genome,…”
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Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma by Linehan, W. Marston, Spellman, Paul T., Ricketts, Christopher J., Creighton, Chad J., Fei, Suzanne S., Davis, Caleb, Wheeler, David A., Murray, Bradley A., Schmidt, Laura, Vocke, Cathy D., Peto, Myron, Al Mamun, Abu Amar M., Shinbrot, Eve, Sethi, Anurag, Brooks, Samira, Rathmell, W. Kimryn, Brooks, Angela N., Hoadley, Katherine A., Robertson, A. Gordon, Brooks, Denise, Bowlby, Reanne, Sadeghi, Sara, Shen, Hui, Weisenberger, Daniel J., Bootwalla, Moiz, Baylin, Stephen B., Laird, Peter W., Cherniack, Andrew D., Saksena, Gordon, Haake, Scott, Li, Jun, Liang, Han, Lu, Yiling, Mills, Gordon B., Akbani, Rehan, Leiserson, Mark D.M., Raphael, Benjamin J., Anur, Pavana, Bottaro, Donald, Albiges, Laurence, Barnabas, Nandita, Choueiri, Toni K., Czerniak, Bogdan, Godwin, Andrew K., Hakimi, A. Ari, Ho, Thai, Hsieh, James, Ittmann, Michael, Kim, William Y., Krishnan, Bhavani, Merino, Maria J., Mills Shaw, Kenna R., Reuter, Victor E., Reznik, Ed, Shelley, Carl Simon, Shuch, Brian, Signoretti, Sabina, Srinivasan, Ramaprasad, Tamboli, Pheroze, Thomas, George, Tickoo, Satish, Burnett, Kenneth, Crain, Daniel, Gardner, Johanna, Lau, Kevin, Mallery, David, Morris, Scott, Paulauskis, Joseph D., Penny, Robert J., Shelton, Candace, Shelton, W. Troy, Sherman, Mark, Thompson, Eric, Yena, Peggy, Avedon, Melissa T., Bowen, Jay, Gastier-Foster, Julie M., Gerken, Mark, Leraas, Kristen M., Lichtenberg, Tara M., Ramirez, Nilsa C., Santos, Tracie, Wise, Lisa, Zmuda, Erik, Demchok, John A., Felau, Ina, Hutter, Carolyn M., Sheth, Margi, Sofia, Heidi J., Tarnuzzer, Roy, Wang, Zhining, Yang, Liming, Zenklusen, Jean C., Zhang, Jiashan (Julia), Ayala, Brenda, Baboud, Julien, Chudamani, Sudha, Liu, Jia, Lolla, Laxmi, Naresh, Rashi

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Whole-genome characterization of lung adenocarcinomas lacking the RTK/RAS/RAF pathway by Carrot-Zhang, Jian, Yao, Xiaotong, Devarakonda, Siddhartha, Deshpande, Aditya, Damrauer, Jeffrey S, Silva, Tiago Chedraoui, Wong, Christopher K, Choi, Hyo Young, Felau, Ina, Robertson, A Gordon, Castro, Mauro A A, Bao, Lisui, Rheinbay, Esther, Liu, Eric Minwei, Trieu, Tuan, Haan, David, Yau, Christina, Hinoue, Toshinori, Liu, Yuexin, Shapira, Ofer, Kumar, Kiran, Mungall, Karen L, Zhang, Hailei, Lee, Jake June-Koo, Berger, Ashton, Gao, Galen F, Zhitomirsky, Binyamin, Liang, Wen-Wei, Zhou, Meng, Moorthi, Sitapriya, Berger, Alice H, Collisson, Eric A, Zody, Michael C, Ding, Li, Cherniack, Andrew D, Getz, Gad, Elemento, Olivier, Benz, Christopher C, Stuart, Josh, Zenklusen, J C, Beroukhim, Rameen, Chang, Jason C, Campbell, Joshua D, Hayes, D Neil, Yang, Lixing, Laird, Peter W, Weinstein, John N, Kwiatkowski, David J, Tsao, Ming S, Travis, William D, Khurana, Ekta, Berman, Benjamin P, Hoadley, Katherine A, Robine, Nicolas, Meyerson, Matthew, Govindan, Ramaswamy, Imielinski, Marcin

“…RTK/RAS/RAF pathway alterations (RPAs) are a hallmark of lung adenocarcinoma (LUAD). In this study, we use whole-genome sequencing (WGS) of 85 cases found to…”
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Abstract 6548: Leveraging compact feature sets for TCGA-based molecular subtype classification on new samples by Ellrott, Kyle, Wong, Chris K., Yau, Christina, Castro, Mauro A., Lee, Jordan, Karlberg, Brian, Grewal, Jasleen K., Lagani, Vincenzo, Tercan, Bahar, Friedl, Verena, Hinoue, Toshinori, Uzunangelov, Vladislav, Westlake, Lindsay, Loinaz, Xavier, Felau, Ina, Wang, Peggy, Kemal, Anab, Caesar-Johnson, Samantha J., Shmulevich, Ilya, Lazar, Alexander J., Tsamardinos, Ioannis, Hoadley, Katherine A., Robertson, Gordon A., Knijnenburg, Theo A., Benz, Christopher C., Stuart, Joshua M., Zenklusen, Jean C., Cherniack, Andrew D., Laird, Peter W.

“…Abstract The NCI's The Cancer Genome Atlas (TCGA) project profiled over 10,000 tumor samples over the course of 10 years. As different tissue-specific working…”
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Analysis of germline-driven ancestry-associated gene expression in cancers by Chambwe, Nyasha, Sayaman, Rosalyn W., Hu, Donglei, Huntsman, Scott, Carrot-Zhang, Jian, Berger, Ashton C., Han, Seunghun, Meyerson, Matthew, Damrauer, Jeffrey S., Hoadley, Katherine A., Felau, Ina, Demchok, John A., Mensah, Michael K.A., Tarnuzzer, Roy, Wang, Zhining, Yang, Liming, Knijnenburg, Theo A., Robertson, A. Gordon, Yau, Christina, Benz, Christopher, Huang, Kuan-lin, Newberg, Justin Y., Frampton, Garrett M., Mashl, R. Jay, Ding, Li, Romanel, Alessandro, Demichelis, Francesca, Zhou, Wanding, Laird, Peter W., Shen, Hui, Wong, Christopher K., Stuart, Joshua M., Lazar, Alexander J., Le, Xiuning, Oak, Ninad, Kemal, Anab, Caesar-Johnson, Samantha, Zenklusen, Jean C., Ziv, Elad, Beroukhim, Rameen, Cherniack, Andrew D.

“…Differential mRNA expression between ancestry groups can be explained by both genetic and environmental factors. We outline a computational workflow to…”
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Analytical protocol to identify local ancestry-associated molecular features in cancer by Carrot-Zhang, Jian, Han, Seunghun, Zhou, Wanding, Damrauer, Jeffrey S., Kemal, Anab, Berger, Ashton C., Meyerson, Matthew, Hoadley, Katherine A., Felau, Ina, Caesar-Johnson, Samantha, Demchok, John A., Mensah, Michael K.A., Tarnuzzer, Roy, Wang, Zhining, Yang, Liming, Zenklusen, Jean C., Chambwe, Nyasha, Knijnenburg, Theo A., Robertson, A. Gordon, Yau, Christina, Benz, Christopher, Huang, Kuan-lin, Newberg, Justin, Frampton, Garret, Mashl, R. Jay, Ding, Li, Romanel, Alessandro, Demichelis, Francesca, Sayaman, Rosalyn W., Ziv, Elad, Laird, Peter W., Shen, Hui, Wong, Christopher K., Stuart, Joshua M., Lazar, Alexander J., Le, Xiuning, Oak, Ninad, Cherniack, Andrew D., Beroukhim, Rameen

“…People of different ancestries vary in cancer risk and outcome, and their molecular differences may indicate sources of these variations. Determining the…”
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