Search Results - "Felı́u, Juan E"
-
1
Rosiglitazone-induced mitochondrial biogenesis in white adipose tissue is independent of peroxisome proliferator-activated receptor γ coactivator-1α
Published in PloS one (07-11-2011)“…Thiazolidinediones, a family of insulin-sensitizing drugs commonly used to treat type 2 diabetes, are thought to exert their effects in part by promoting…”
Get full text
Journal Article -
2
Gene expression profiling in hearts of diabetic mice uncovers a potential role of estrogen-related receptor γ in diabetic cardiomyopathy
Published in Molecular and cellular endocrinology (15-07-2016)“…Diabetic cardiomyopathy is characterized by an abnormal oxidative metabolism, but the underlying mechanisms remain to be defined. To uncover potential…”
Get full text
Journal Article -
3
Involvement of Both Phosphatidylinositol 3-Kinase and p44/p42 Mitogen-Activated Protein Kinase Pathways in the Short-Term Regulation of Pyruvate Kinase L by Insulin
Published in Endocrinology (Philadelphia) (01-03-2001)“…Abstract Pyruvate kinase L (PK-L) is a key regulatory enzyme of the hepatic glycolytic/gluconeogenic pathway that can be dephosphorylated and activated in…”
Get full text
Journal Article -
4
Decreased responsiveness of gluconeogenesis to the modulation by sulfonylureas in hepatocytes isolated from obese ( fa/ fa) zucker rats
Published in Life sciences (1973) (23-02-2001)“…The influence of the hypoglycemic agent glipizide (0–100 μM) on the rate of gluconeogenesis from lactate, as well as on the levels of fructose…”
Get full text
Journal Article -
5
Sulfonylurea effects on acid and pepsinogen secretion in isolated rabbit gastric glands
Published in European journal of pharmacology (19-02-1998)“…The influence of different sulfonylureas on the rate of acid and pepsinogen secretion was studied in isolated rabbit gastric glands. Neither tolbutamide…”
Get full text
Journal Article -
6
Modulation of Epinephrine-Stimulated Gluconeogenesis by Insulin in Hepatocytes Isolated from Genetically Obese (fa/fa) Zucker Rats
Published in Endocrinology (Philadelphia) (01-06-1997)“…Abstract Genetically obese (fa/fa) Zucker rats present an impaired response of hepatic glucose production to the inhibition by insulin. In this work, we have…”
Get full text
Journal Article -
7
Inhibition of acid secretion by the nonsteroidal anti-inflammatory drugs diclofenac and piroxicam in isolated gastric glands: analysis of a multifocal mechanism
Published in American journal of physiology: Gastrointestinal and liver physiology (01-05-2004)“…In nonstimulated rabbit gastric glands, acetylsalicylic acid (10-500 microM) and indomethacin (3-300 microM) did not significantly modify the basal rate of…”
Get more information
Journal Article -
8
Rosiglitazone-Induced Mitochondrial Biogenesis in White Adipose Tissue Is Independent of Peroxisome Proliferator-Activated Receptor [gamma] Coactivator-1[alpha]
Published in PloS one (07-11-2011)“…Background Thiazolidinediones, a family of insulin-sensitizing drugs commonly used to treat type 2 diabetes, are thought to exert their effects in part by…”
Get full text
Journal Article -
9
Sulfonylureas activate glycogen phosphorylase and increase cytosolic free-Ca2+ levels in isolated rat hepatocytes
Published in Metabolism, clinical and experimental (01-05-1993)“…Without causing significant changes in cellular levels of cyclic adenosine monophosphate (cAMP), the addition of either glibenclamide or gliquidone to isolated…”
Get more information
Journal Article -
10
Involvement of Both Phosphatidylinositol 3-Kinase and p44/p42 Mitogen-Activated Protein Kinase Pathways in the Short-Term Regulation of Pyruvate Kinase L by Insulin1
Published in Endocrinology (Philadelphia) (01-03-2001)“…Pyruvate kinase L (PK-L) is a key regulatory enzyme of the hepatic glycolytic/gluconeogenic pathway that can be dephosphorylated and activated in response to…”
Get full text
Journal Article -
11
Pyruvate Kinase
Published in European journal of biochemistry (01-08-1973)“…Kinetic studies of the pyruvate kinases of rat and human tissues have led to the identification of three classes of isoenzymes with qualitative differences in…”
Get full text
Journal Article -
12
Impairment of H+-K+-ATPase-dependent proton transport and inhibition of gastric acid secretion by ethanol
Published in American journal of physiology: Gastrointestinal and liver physiology (01-06-2001)“…Ethanol (1-20% vol/vol) caused a dose-dependent reduction in the basal rate of acid formation in isolated rabbit gastric glands with a calculated EC(50) value…”
Get more information
Journal Article -
13
Modulation of Epinephrine-Stimulated Gluconeogenesis by Insulin in Hepatocytes Isolated from Genetically Obese (fa/fa) Zucker Rats1
Published in Endocrinology (Philadelphia) (01-06-1997)“…Genetically obese (fa/fa) Zucker rats present an impaired response of hepatic glucose production to the inhibition by insulin. In this work, we have…”
Get full text
Journal Article -
14
Modulation of Gluconeogenesis by Epinephrine in Hepatocytes Isolated from Genetically Obese (fa/fa) Zucker Rats
Published in Archives of biochemistry and biophysics (01-01-2000)“…The obese (fa/fa) Zucker rat shows an impaired sympathetic tone which is accompanied by an altered thermogenesis and changes in both lipid and carbohydrate…”
Get full text
Journal Article -
15
Modulation of glycogen phosphorylase activity and fructose 2,6-bisphosphate levels by glibenclamide and meglitinide in isolated rat hepatocytes: A comparative study
Published in Metabolism, clinical and experimental (01-08-1995)“…The influence of glibenclamide and meglitinide, or 4-[2-(5-chloro-2-methoxybenzamide)ethyl]-benzoic acid, a compound similar to the nonsulfonylurea moiety of…”
Get full text
Journal Article -
16
Impairment of glycosyl-phosphatidylinositol-dependent insulin signaling system in isolated rat hepatocytes by streptozotocin-induced diabetes
Published in Endocrinology (Philadelphia) (01-10-1992)“…The addition to different types of cells of an inositol-phosphate glycan, generated by the phospholipase C-catalyzed hydrolysis of a insulin-sensitive…”
Get more information
Journal Article -
17
Hormonal Control of Pyruvate Kinase Activity and of Gluconeogenesis in Isolated Hepatocytes
Published in Proceedings of the National Academy of Sciences - PNAS (01-08-1976)“…Treatment of isolated rat hepatocytes with saturating concentrations of glucagon caused several modifications in the kinetic properties of pyruvate kinase…”
Get full text
Journal Article -
18
A phospho-oligosaccharide mimics insulin action on glycogen phosphorylase and pyruvate kinase activities in isolated rat hepatocytes
Published in Biochemical and biophysical research communications (15-09-1987)“…A phospho-oligosaccharide which is the polar head group of a novel insulin-sensitive glycophospholipid has recently been involved in insulin action. We have…”
Get more information
Journal Article -
19
Fructose 2,6-bisphosphate levels and modulation of glycolysis by histamine, cholecystokinin, and forskolin in isolated rabbit gastric glands
Published in Metabolism, clinical and experimental (01-03-1992)“…In isolated rabbit gastric glands incubated in the presence of 1 mmol/L glucose, the content of fructose 2,6-bisphosphate (F-2,6-P2) was 5.7 +/- 0.5 pmol/mg…”
Get more information
Journal Article -
20
Effect of streptozotocin diabetes on the glycolytic flux and on fructose 2,6-bisphosphate levels in isolated rat enterocytes
Published in Metabolism, clinical and experimental (01-08-1990)“…In epithelial cells isolated from rat small intestine and incubated in the presence of 1 mM glucose, streptozotocin-induced diabetes reduced, by 46 and 29%,…”
Get more information
Journal Article