Search Results - "Felício, Mário R"
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Designing improved active peptides for therapeutic approaches against infectious diseases
Published in Biotechnology advances (01-03-2018)“…Infectious diseases are one of the main causes of human morbidity and mortality. In the last few decades, pathogenic microorganisms' resistance to conventional…”
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Application of Light Scattering Techniques to Nanoparticle Characterization and Development
Published in Frontiers in chemistry (25-06-2018)“…Over the years, the scientific importance of nanoparticles for biomedical applications has increased. The high stability and biocompatibility, together with…”
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Peptides with Dual Antimicrobial and Anticancer Activities
Published in Frontiers in chemistry (2017)“…In recent years, the number of people suffering from cancer and multi-resistant infections has increased, such that both diseases are already seen as current…”
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Synergistic and antibiofilm activity of the antimicrobial peptide P5 against carbapenem-resistant Pseudomonas aeruginosa
Published in Biochimica et biophysica acta. Biomembranes (01-07-2019)“…In the search for new antimicrobial molecules, antimicrobial peptides (AMPs) offer a viable alternative to conventional antibiotics, as they physically disrupt…”
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New frontiers for anti-biofilm drug development
Published in Pharmacology & therapeutics (Oxford) (01-04-2016)“…Pathogenic microbial biofilm, a consortium of microbial cells protected by a self-produced polymer matrix, is considered a worldwide challenge due to the…”
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EcDBS1R4, an antimicrobial peptide effective against Escherichia coli with in vitro fusogenic ability
Published in International journal of molecular sciences (30-11-2020)“…©2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open accessarticle distributed under the terms and conditions of the Creative…”
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Psd1 Effects on Candida albicans Planktonic Cells and Biofilms
Published in Frontiers in cellular and infection microbiology (09-06-2017)“…Candida albicans is an important human pathogen, causing opportunistic infections. The adhesion of planktonic cells to a substrate is the first step for…”
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Polyalanine peptide variations may have different mechanisms of action against multidrug-resistant bacterial pathogens
Published in Journal of antimicrobial chemotherapy (13-04-2021)“…Abstract Objectives The number of bacterial pathogens resistant to the currently available antibiotics has dramatically increased, with antimicrobial peptides…”
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Psd2 pea defensin shows a preference for mimetic membrane rafts enriched with glucosylceramide and ergosterol
Published in Biochimica et biophysica acta. Biomembranes (01-04-2019)“…Psd2 is a pea defensin with 47 amino acid residues that inhibits the growth of fungal species by an uncharacterized mechanism. In this work, Psd2 interactions…”
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Neuropeptide receptors as potential pharmacological targets for obesity
Published in Pharmacology & therapeutics (Oxford) (01-04-2019)“…Obesity is a chronic multifactorial disease, characterized by an excessive accumulation of adipose tissue. It is usually the result of excessive food intake…”
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Antimicrobial Peptides: Effect on Bacterial Cells
Published in Methods in molecular biology (Clifton, N.J.) (2019)“…Antimicrobial peptides (AMPs) are one of the most promising alternatives to conventional antibiotics. Atomic force microscopy (AFM), as imaging and force…”
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Corrigendum: A polyalanine peptide derived from polar fish with anti-infectious activities
Published in Scientific reports (20-07-2016)Get full text
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Fast and potent bactericidal membrane lytic activity of PaDBS1R1, a novel cationic antimicrobial peptide
Published in Biochimica et biophysica acta. Biomembranes (01-01-2019)“…Antimicrobial peptides (AMPs) are promising candidates for the development of future antibiotics. In an attempt to increase the efficacy of therapeutic AMPs,…”
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Selective antibacterial activity of the cationic peptide PaDBS1R6 against Gram-negative bacteria
Published in Biochimica et biophysica acta. Biomembranes (01-07-2019)“…Infections caused by Gram-negative bacteria, Escherichia coli and Pseudomonas aeruginosa foremost among them, constitute a major worldwide health problem…”
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Structural and functional evaluation of the palindromic alanine-rich antimicrobial peptide Pa-MAP2
Published in Biochimica et biophysica acta (01-07-2016)“…Recently, several peptides have been studied regarding the defence process against pathogenic microorganisms, which are able to act against different targets,…”
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A polyalanine peptide derived from polar fish with anti-infectious activities
Published in Scientific reports (26-02-2016)“…Due to the growing concern about antibiotic-resistant microbial infections, increasing support has been given to new drug discovery programs. A promising…”
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Pa-MAP 1.5 and 1.9: Mechanisms of Action of two Antimicrobial Peptides
Published in Biophysical journal (16-02-2016)Get full text
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PSD1 Antimicrobial Activity Against Candida Albicans Planktonic Cells and Biofilms
Published in Biophysical journal (16-02-2016)Get full text
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Correction: Corrigendum: A polyalanine peptide derived from polar fish with anti-infectious activities
Published in Scientific reports (20-07-2016)“…Scientific Reports 6: Article number: 21385; published online: 26 February 2016; updated: 20 July 2016 In this Article, there is a typographical error in the…”
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Ps d1 Effects on Candida albicans Planktonic Cells and Biofilms
Published in Frontiers in cellular and infection microbiology (2017)“…is an important human pathogen, causing opportunistic infections. The adhesion of planktonic cells to a substrate is the first step for biofilm development…”
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