Search Results - "Fekete, Emily E F"

Fatty acid transport protein inhibition sensitizes breast and ovarian cancers to oncolytic virus therapy via lipid modulation of the tumor microenvironment by Surendran, Abera, Jamalkhah, Monire, Poutou, Joanna, Birtch, Rayanna, Lawson, Christine, Dave, Jaahnavi, Crupi, Mathieu J F, Mayer, Justin, Taylor, Victoria, Petryk, Julia, de Souza, Christiano Tanese, Moodie, Neil, Billingsley, Jacob Lecompte, Austin, Bradley, Cormack, Nicole, Blamey, Natalie, Rezaei, Reza, McCloskey, Curtis W, Fekete, Emily E F, Birdi, Harsimrat K, Neault, Serge, Jamieson, Taylor R, Wylie, Brenna, Tucker, Sarah, Azad, Taha, Vanderhyden, Barbara, Tai, Lee-Hwa, Bell, John C, Ilkow, Carolina S

“…Adipocytes in the tumour microenvironment are highly dynamic cells that have an established role in tumour progression, but their impact on anti-cancer therapy…”
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CRISPR-mediated rapid arming of poxvirus vectors enables facile generation of the novel immunotherapeutic STINGPOX by Whelan, Jack T, Singaravelu, Ragunath, Wang, Fuan, Pelin, Adrian, Tamming, Levi A, Pugliese, Giuseppe, Martin, Nikolas T, Crupi, Mathieu J F, Petryk, Julia, Austin, Bradley, He, Xiaohong, Marius, Ricardo, Duong, Jessie, Jones, Carter, Fekete, Emily E F, Alluqmani, Nouf, Chen, Andrew, Boulton, Stephen, Huh, Michael S, Tang, Matt Y, Taha, Zaid, Scut, Elena, Diallo, Jean-Simon, Azad, Taha, Lichty, Brian D, Ilkow, Carolina S, Bell, John C

“…Poxvirus vectors represent versatile modalities for engineering novel vaccines and cancer immunotherapies. In addition to their oncolytic capacity and…”
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SARS-CoV-2 S1 NanoBiT: A nanoluciferase complementation-based biosensor to rapidly probe SARS-CoV-2 receptor recognition by Azad, Taha, Singaravelu, Ragunath, Fekete, Emily E.F., Taha, Zaid, Rezaei, Reza, Arulanandam, Rozanne, Boulton, Stephen, Diallo, Jean-Simon, Ilkow, Carolina S., Bell, John C.

“…As the COVID-19 pandemic continues, there is an imminent need for rapid diagnostic tools and effective antivirals targeting SARS-CoV-2. We have developed a…”
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Nanoluciferase complementation-based bioreporter reveals the importance of N-linked glycosylation of SARS-CoV-2 S for viral entry by Azad, Taha, Singaravelu, Ragunath, Taha, Zaid, Jamieson, Taylor R., Boulton, Stephen, Crupi, Mathieu J.F., Martin, Nikolas T., Fekete, Emily E.F., Poutou, Joanna, Ghahremani, Mina, Pelin, Adrian, Nouri, Kazem, Rezaei, Reza, Marshall, Christopher Boyd, Enomoto, Masahiro, Arulanandam, Rozanne, Alluqmani, Nouf, Samson, Reuben, Gingras, Anne-Claude, Cameron, D. William, Greer, Peter A., Ilkow, Carolina S., Diallo, Jean-Simon, Bell, John C.

“…The ongoing COVID-19 pandemic has highlighted the immediate need for the development of antiviral therapeutics targeting different stages of the SARS-CoV-2…”
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Single-dose replicating poxvirus vector-based RBD vaccine drives robust humoral and T cell immune response against SARS-CoV-2 infection by Boulton, Stephen, Poutou, Joanna, Martin, Nikolas T., Azad, Taha, Singaravelu, Ragunath, Crupi, Mathieu J.F., Jamieson, Taylor, He, Xiaohong, Marius, Ricardo, Petryk, Julia, Tanese de Souza, Christiano, Austin, Bradley, Taha, Zaid, Whelan, Jack, Khan, Sarwat T., Pelin, Adrian, Rezaei, Reza, Surendran, Abera, Tucker, Sarah, Fekete, Emily E.F., Dave, Jaahnavi, Diallo, Jean-Simon, Auer, Rebecca, Angel, Jonathan B., Cameron, D. William, Cailhier, Jean-Francois, Lapointe, Réjean, Potts, Kyle, Mahoney, Douglas J., Bell, John C., Ilkow, Carolina S.

“…The coronavirus disease 2019 (COVID-19) pandemic requires the continued development of safe, long-lasting, and efficacious vaccines for preventive responses to…”
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Identification of FDA-approved bifonazole as a SARS-CoV-2 blocking agent following a bioreporter drug screen by Taha, Zaid, Arulanandam, Rozanne, Maznyi, Glib, Godbout, Elena, Carter-Timofte, Madalina E., Kurmasheva, Naziia, Reinert, Line S., Chen, Andrew, Crupi, Mathieu J.F., Boulton, Stephen, Laroche, Geneviève, Phan, Alexandra, Rezaei, Reza, Alluqmani, Nouf, Jirovec, Anna, Acal, Alexandra, Fekete, Emily E.F., Singaravelu, Ragunath, Petryk, Julia, Idorn, Manja, Potts, Kyle G., Todesco, Hayley, John, Cini, Mahoney, Douglas J., Ilkow, Carolina S., Giguère, Patrick, Alain, Tommy, Côté, Marceline, Paludan, Søren R., Olagnier, David, Bell, John C., Azad, Taha, Diallo, Jean-Simon

“…We established a split nanoluciferase complementation assay to rapidly screen for inhibitors that interfere with binding of the receptor binding domain (RBD)…”
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Assessing fecal metaproteomics workflow and small protein recovery using DDA and DIA PASEF mass spectrometry by Wang, Angela, Fekete, Emily E F, Creskey, Marybeth, Cheng, Kai, Ning, Zhibin, Pfeifle, Annabelle, Li, Xuguang, Figeys, Daniel, Zhang, Xu

“…This study aims to evaluate the impact of experimental workflow on fecal metaproteomic observations, including the recovery of small and antimicrobial proteins…”
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Lipid nanoparticle encapsulation of a Delta spike-CD40L DNA vaccine improves effectiveness against Omicron challenge in Syrian hamsters by Tamming, Levi, Duque, Diana, Tran, Anh, Lansdell, Casey, Frahm, Grant, Wu, Jianguo, Fekete, Emily E.F., Creskey, Marybeth, Thulasi Raman, Sathya N., Laryea, Emmanuel, Zhang, Wanyue, Pfeifle, Annabelle, Gravel, Caroline, Stalker, Andrew, Hashem, Anwar M., Chen, Wangxue, Stuible, Matthew, Durocher, Yves, Safronetz, David, Cao, Jingxin, Wang, Lisheng, Sauve, Simon, Rosu-Myles, Michael, Zhang, Xu, Johnston, Michael J.W., Li, Xuguang

“…The effectiveness of mRNA vaccines largely depends on their lipid nanoparticle (LNP) component. Herein, we investigate the effectiveness of DLin-KC2-DMA (KC2)…”
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An economic and robust TMT labeling approach for high throughput proteomic and metaproteomic analysis by Creskey, Marybeth, Li, Leyuan, Ning, Zhibin, Fekete, Emily Ef, Mayne, Janice, Walker, Krystal, Ampaw, Anna, Ben, Robert, Zhang, Xu, Figeys, Daniel

“…Multiplexed quantitative proteomics using tandem mass tag (TMT) is increasingly used in -omic study of complex samples. While TMT-based proteomics has the…”
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