Search Results - "Fejgin, K"
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15q13.3 homozygous knockout mouse model display epilepsy-, autism- and schizophrenia-related phenotypes
Published in Translational psychiatry (26-07-2016)“…The 15q13.3 microdeletion syndrome is caused by a 1.5-MB hemizygous microdeletion located on 15q13.3 affecting seven genes: FAN1 ; MTMR10 ; TRPM1 ; miR-211 ;…”
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P.3.c.074 L-lysine as an add-on treatment in patients with schizophrenia
Published in European neuropsychopharmacology (2009)Get full text
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The importance of nitric oxide in social dysfunction
Published in Behavioural brain research (08-06-2009)“…Schizophrenia is a chronic disorder generally considered to encompass positive symptoms, negative symptoms and cognitive deficits. Increasing attention has…”
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Restricted Cortical and Amygdaloid Removal of Vesicular Glutamate Transporter 2 in Preadolescent Mice Impacts Dopaminergic Activity and Neuronal Circuitry of Higher Brain Function
Published in The Journal of neuroscience (18-02-2009)“…A major challenge in neuroscience is to resolve the connection between gene functionality, neuronal circuits, and behavior. Most, if not all, neuronal circuits…”
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Phencyclidine affects memory in a nitric oxide-dependent manner: Working and reference memory
Published in Behavioural brain research (01-11-2006)“…Phencyclidine (PCP), a non-competitive NMDA receptor antagonist, was used to model schizophrenia-like cognitive dysfunctions of learning and memory in rats…”
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L-lysine as adjunctive treatment in patients with schizophrenia: a single-blinded, randomized, cross-over pilot study
Published in BMC medicine (18-04-2011)“…Accumulating evidence suggests that the brain's nitric oxide (NO) signalling system may be involved in the pathophysiology of schizophrenia and could thus…”
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Effects of phencyclidine on spatial learning and memory: Nitric oxide-dependent mechanisms
Published in Behavioural brain research (15-07-2006)“…Cognitive deficits of schizophrenia constitute a disabling part of the disease predicting treatment success as well as functional outcome. Phencyclidine (PCP),…”
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Nitric oxide synthase inhibition attenuates phencyclidine-induced disruption of cognitive flexibility
Published in Pharmacology, biochemistry and behavior (01-05-2008)“…Schizophrenia encompasses, amongst other symptoms, a heavy load of cognitive dysfunctionality. Using the psychotomimetic agent, phencyclidine (PCP), we have…”
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Activation of a nitric-oxide-sensitive camp pathway with phencyclidine : Elevated hippocampal camp levels are temporally associated with deficits in prepulse inhibition
Published in Psychopharmacologia (01-05-2005)“…Schizophrenic patients show deficits in pre-attentive information processing as evidenced, for example, by disrupted prepulse inhibition, a measure of…”
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