Search Results - "Feitelson, Mark A."

Pathogenic mechanisms in HBV- and HCV-associated hepatocellular carcinoma by Arzumanyan, Alla, Reis, Helena M. G. P. V., Feitelson, Mark A.

“…Key Points Hepatitis B virus (HBV) and hepatitis C virus (HCV) are major aetiological agents of chronic liver disease and hepatocellular carcinoma (HCC). HCC…”
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Sustained proliferation in cancer: Mechanisms and novel therapeutic targets by Feitelson, Mark A, Arzumanyan, Alla, Kulathinal, Rob J, Blain, Stacy W, Holcombe, Randall F, Mahajna, Jamal, Marino, Maria, Martinez-Chantar, Maria L, Nawroth, Roman, Sanchez-Garcia, Isidro, Sharma, Dipali, Saxena, Neeraj K, Singh, Neetu, Vlachostergios, Panagiotis J, Guo, Shanchun, Honoki, Kanya, Fujii, Hiromasa, Georgakilas, Alexandros G, Bilsland, Alan, Amedei, Amedeo, Niccolai, Elena, Amin, Amr, Ashraf, S. Salman, Boosani, Chandra S, Guha, Gunjan, Ciriolo, Maria Rosa, Aquilano, Katia, Chen, Sophie, Mohammed, Sulma I, Azmi, Asfar S, Bhakta, Dipita, Halicka, Dorota, Keith, W. Nicol, Nowsheen, Somaira

“…Abstract Proliferation is an important part of cancer development and progression. This is manifest by altered expression and/or activity of cell cycle related…”
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Hepatitis B x antigen (HBx) is an important therapeutic target in the pathogenesis of hepatocellular carcinoma by Medhat, Arvin, Arzumanyan, Alla, Feitelson, Mark A.

“…Hepatitis B virus (HBV) is a human pathogen that has infected an estimated two billion people worldwide. Despite the availability of highly efficacious…”
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Role of miR-148a in hepatitis B associated hepatocellular carcinoma by Yuan, Ke, Lian, Zhaorui, Sun, Bill, Clayton, Marcia M, Ng, Irene O L, Feitelson, Mark A

“…Hepatitis B virus encoded X antigen (HBx) is a trans-regulatory protein that alters the activity of selected transcription factors and cytoplasmic signal…”
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Editorial: Microbiome metabolites in health and disease by Canfora, Emanuel E., Feitelson, Mark A., Arzumanyan, Alla

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Preclinical Characterization of GLS4, an Inhibitor of Hepatitis B Virus Core Particle Assembly by Wu, Guoyi, Liu, Bo, Zhang, Yingjun, Li, Jing, Arzumanyan, Alla, Clayton, Marcia M, Schinazi, Raymond F, Wang, Zhaohe, Goldmann, Siegfried, Ren, Qingyun, Zhang, Faxhou, Feitelson, Mark A

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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The roles of hepatitis B virus-encoded X protein in virus replication and the pathogenesis of chronic liver disease by Feitelson, Mark A, Bonamassa, Barbara, Arzumanyan, Alla

“…Hepatitis B virus (HBV) is a major cause of chronic liver disease (CLD) and hepatocellular carcinoma (HCC) worldwide. More than 350 million people are at risk…”
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Does the Hepatitis B Antigen HBx Promote the Appearance of Liver Cancer Stem Cells? by ARZUMANYAN, Alla, FRIEDMAN, Tiffany, NG, Irene O. L, CLAYTON, Marcia M, ZHAORUI LIAN, FEITELSON, Mark A

“…Hepatitis B virus (HBV) is a major etiologic agent of chronic liver disease and hepatocellular carcinoma (HCC). HBV-encoded X antigen, HBx, and pathways…”
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Hepatitis B x (HBx) as a Component of a Functional Cure for Chronic Hepatitis B by Feitelson, Mark A, Arzumanyan, Alla, Spector, Ira, Medhat, Arvin

“…Patients who are carriers of the hepatitis B virus (HBV) are at high risk of chronic liver disease (CLD) which proceeds from hepatitis, to fibrosis, cirrhosis…”
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Studies on the Efficacy, Potential Cardiotoxicity and Monkey Pharmacokinetics of GLP-26 as a Potent Hepatitis B Virus Capsid Assembly Modulator by Hurwitz, Selwyn J, McBrearty, Noreen, Arzumanyan, Alla, Bichenkov, Eugene, Tao, Sijia, Bassit, Leda, Chen, Zhe, Kohler, James J, Amblard, Franck, Feitelson, Mark A, Schinazi, Raymond F

“…While treatment options are available for hepatitis B virus (HBV), there is currently no cure. Anti-HBV nucleoside analogs and interferon-alpha 2b rarely clear…”
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Tupaia CD81, SR-BI, Claudin-1, and Occludin Support Hepatitis C Virus Infection by YIMIN TONG, YONGZHE ZHU, FEITELSON, Mark A, PING ZHAO, QI, Zhong-Tian, XUESHAN XIA, YUAN LIU, YUE FENG, XIAN HUA, ZHIHUI CHEN, HUI DING, LI GAO, YONGZHI WANG

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Human Viral Oncogenesis: A Cancer Hallmarks Analysis by Mesri, Enrique A., Feitelson, Mark A., Munger, Karl

“…Approximately 12% of all human cancers are caused by oncoviruses. Human viral oncogenesis is complex, and only a small percentage of the infected individuals…”
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COOH-terminal deletion of HBx gene is a frequent event in HBV-associated hepatocellular carcinoma by Liu, Xiao-Hong, Lin, Jing, Zhang, Shu-Hui, Zhang, Shun-Min, Feitelson, Mark-A, Gao, Heng-Jun, Zhu, Ming-Hua

“…AIM：To investigate the hepatitis B virus （HBV） x gene （HBx） state in the tissues of HBV-related hepatocellular carcinoma （HCC） in Chinese patients and whether…”
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A spiroligomer α-helix mimic that binds HDM2, penetrates human cells and stabilizes HDM2 in cell culture by Brown, Zachary Z, Akula, Kavitha, Arzumanyan, Alla, Alleva, Jennifer, Jackson, Marcus, Bichenkov, Eugeney, Sheffield, Joel B, Feitelson, Mark A, Schafmeister, Christian E

“…We demonstrate functionalized spiroligomers that mimic the HDM2-bound conformation of the p53 activation domain. Spiroligomers are stereochemically defined,…”
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Short-chain fatty acids in cancer pathogenesis by Feitelson, Mark A., Arzumanyan, Alla, Medhat, Arvin, Spector, Ira

“…Cancer is a multi-step process that can be viewed as a cellular and immunological shift away from homeostasis in response to selected infectious agents,…”
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Hepatitis C virus targets over‐expression of arginase I in hepatocarcinogenesis by Cao, Wenjun, Sun, Bill, Feitelson, Mark A., Wu, Tong, Tur‐Kaspa, Ran, Fan, Qishi

“…Hepatitis C virus (HCV) infection is often associated with chronic liver disease, which is a major risk factor for the development of hepatocellular carcinoma…”
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Evaluation of Single and Combination Therapies with Tenofovir Disoproxil Fumarate and Emtricitabine In Vitro and in a Robust Mouse Model Supporting High Levels of Hepatitis B Virus Replication by SCHINAZI, Raymond F, BASSIT, Leda, CLAYTON, Marcia M, SUN, Bill, KOHLER, James J, OBIKHOD, Aleksandr, ARZUMANYAN, Alla, FEITELSON, Mark A

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Hepatitis B virus integration, fragile sites, and hepatocarcinogenesis by Feitelson, Mark A, Lee, Jungmin

“…Abstract Chronic liver disease associated with long term hepatitis B virus (HBV) infection contributes importantly to the development of hepatocellular…”
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Oxidative stress and antioxidants in hepatic pathogenesis by Ha, Hye-Lin, Shin, Hye-Jun, Feitelson, Mark A, Yu, Dae-Yeul

“…Long term hepatitis B virus (HBV) infection is a major risk factor in pathogenesis of chronic liver diseases, including hepatocellular carcinoma (HCC). The HBV…”
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Early molecular and genetic determinants of primary liver malignancy by Feitelson, Mark A, Pan, Jingbo, Lian, Zhaorui

“…Although the overview above provides a partial molecular picture of the early stages of stepwise hepatocarcinogenesis. it should be emphasized that tumor and…”
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