Search Results - "Feingold, K."

Topical applications of an emollient reduce circulating pro‐inflammatory cytokine levels in chronically aged humans: a pilot clinical study by Ye, L., Mauro, T.M., Dang, E., Wang, G., Hu, L.Z., Yu, C., Jeong, S., Feingold, K., Elias, P.M., Lv, C.Z., Man, M.Q.

“…Background While increased levels of circulating inflammatory cytokines in chronologically aged humans have been linked to the development of ageing‐associated…”
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Leptin regulation of the immune response and the immunodeficiency of malnutrition by Faggioni, R, Feingold, K R, Grunfeld, C

“…Leptin is a 16 kDa protein mainly produced by adipose tissue in proportion to adipose tissue mass. Originally thought to be a satiety factor, leptin is a…”
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Variation of skin surface pH, sebum content and stratum corneum hydration with age and gender in a large Chinese population by Man, M Q, Xin, S J, Song, S P, Cho, S Y, Zhang, X J, Tu, C X, Feingold, K R, Elias, P M

“…Evidence suggests the importance of skin biophysical properties in predicting diseases and in developing appropriate skin care. The results to date of studies…”
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Infection and Inflammation-Induced Proatherogenic Changes of Lipoproteins by Khovidhunkit, Weerapan, Memon, Riaz A., Feingold, Kenneth R., Grunfeld, Carl

“…Epidemiologic studies suggest a link between infection/inflammation and atherosclerosis. During the acute-phase response to infection and inflammation,…”
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Low Humidity Stimulates Epidermal DNA Synthesis and Amplifies the Hyperproliferative Response to Barrier Disruption: Implication for Seasonal Exacerbations of Inflammatory Dermatoses by Denda, Mitsuhiro, Sato, Junko, Tsuchiya, Toru, Elias, Peter M., Feingold, Kenneth R.

“…Although seasonal changes in humidity are thought to exacerbate various skin diseases, whether these flares can be attributed to prolonged exposure to extremes…”
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Reduced Leptin Levels in Starvation Increase Susceptibility to Endotoxic Shock by Faggioni, Raffaella, Moser, Arthur, Feingold, Kenneth R., Grunfeld, Carl

“…Malnutrition compromises immune function, reducing resistance to infection. We examine whether the decrease in leptin induced by starvation increases…”
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Extracellular pH Controls NHE1 Expression in Epidermis and Keratinocytes: Implications for Barrier Repair by Hachem, J.-P., Behne, M., Aronchik, I., Demerjian, M., Feingold, K.R., Elias, P.M., Mauro, T.M.

“…We have previously shown that the Na+/H+ antiporter (NHE1) is an essential endogenous pathway responsible for stratum corneum (SC) acidification. Since the…”
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Exposure to a Dry Environment Enhances Epidermal Permeability Barrier Function by Denda, Mitsuhiro, Sato, Junko, Masuda, Yoshiko, Tsuchiya, Toru, Koyama, Junichi, Kuramoto, Masato, Elias, Peter M., Feingold, Kenneth R.

“…Previous studies have suggested that transepidermal water movement may play an important role in epidermal homeostasis and barrier repair. Here we analyzed…”
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25 Hydroxyvitamin D 1 α-Hydroxylase Is Required for Optimal Epidermal Differentiation and Permeability Barrier Homeostasis by Bikle, D.D., Chang, S., Crumrine, D., Elalieh, H., Man, M.-Q., Choi, E.H., Dardenne, O., Xie, Z., Arnaud, R. St, Feingold, K., Elias, P.M.

“…Keratinocytes express high levels of 25OHD 1α-hydroxylase (1OHase). The product of this enzyme, 1,25-dihydroxyvitamin D (1,25(OH)2D), promotes the…”
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What is the 'true' function of skin? by Chuong, C M, Nickoloff, B J, Elias, P M, Goldsmith, L A, Macher, E, Maderson, P A, Sundberg, J P, Tagami, H, Plonka, P M, Thestrup-Pederson, K, Bernard, B A, Schröder, J M, Dotto, P, Chang, C M, Williams, M L, Feingold, K R, King, L E, Kligman, A M, Rees, J L, Christophers, E

“…Conventional textbook wisdom portrays the skin as an organ that literally enwraps whatever each of us stands for as a more or less functional, individual…”
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Paraoxonase activity in the serum and hepatic mRNA levels decrease during the acute phase response by Feingold, Kenneth R, Memon, Riaz A, Moser, Arthur H, Grunfeld, Carl

“…Numerous epidemiological studies have suggested an association between the acute phase response and atherosclerosis. Paraoxonase (PON) is an HDL associated…”
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Lipopenia and Skin Barrier Abnormalities in DGAT2-deficient Mice by Stone, Scot J., Myers, Heather M., Watkins, Steven M., Brown, Barbara E., Feingold, Kenneth R., Elias, Peter M., Farese, Robert V.

“…The synthesis of triglycerides is catalyzed by two known acyl-CoA:diacylglycerol acyltransferase (DGAT) enzymes. Although they catalyze the same biochemical…”
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The aged epidermal permeability barrier. Structural, functional, and lipid biochemical abnormalities in humans and a senescent murine model by Ghadially, R, Brown, B E, Sequeira-Martin, S M, Feingold, K R, Elias, P M

“…Aged epidermis displays altered drug permeability, increased susceptibility to irritant contact dermatitis, and often severe xerosis, suggesting compromise of…”
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LPS-induced anorexia in leptin-deficient (ob/ob) and leptin receptor-deficient (db/db) mice by Faggioni, R. (University of California, San Francisco, CA.), Fuller, J, Moser, A, Feingold, K.R, Grunfeld, C

“…Administration of endotoxin (lipopolysaccharide, LPS) induces profound anorexia. Injection of leptin decreases food intake in mice. Recently, we reported that…”
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Potassium channel openers accelerate epidermal barrier recovery by Denda, M., Tsutsumi, M., Inoue, K., Crumrine, D., Feingold, K.R., Elias, P.M.

“…Summary Background  Maintenance of a competent permeability barrier in the face of external and internal stressors requires signals between the stratum corneum…”
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Role for circulating lipoproteins in protection from endotoxin toxicity by FEINGOLD, K. R, FUNK, J. L, MOSER, A. H, SHIGENAGA, J. K, RAPP, J. H, GRUNFELD, C

“…Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon…”
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Role of cytokines in inducing hyperlipidemia by FEINGOLD, K. R, GRUNFELD, C

“…Plasma lipid levels are elevated in people with diabetes, and a direct relationship can be demonstrated between indices of diabetic control and plasma lipid…”
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Cutaneous Barrier perturbation stimulates cytokine production in the epidermis of mice by WOOD, L. C, JACKSON, S. M, ELIAS, P. M, GRUNFELD, C, FEINGOLD, K. R

“…The disruption of the cutaneous permeability barrier results in metabolic events that ultimately restore barrier function. These include increased epidermal…”
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Inadequate treatment with HMG-CoA reductase inhibitors by health care providers by Marcelino, J J, Feingold, K R

“…To determine if patients treated with HMG-CoA reductase inhibitors have their LDL cholesterol levels at or below the levels recommended by the National…”
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Endotoxin rapidly induces changes in lipid metabolism that produce hypertriglyceridemia: low doses stimulate hepatic triglyceride production while high doses inhibit clearance by Feingold, KR, Staprans, I, Memon, RA, Moser, AH, Shigenaga, JK, Doerrler, W, Dinarello, CA, Grunfeld, C

“…Hyperlipidemia frequently accompanies infectious diseases and may be due to increases in lipoprotein production or decreases in lipoprotein clearance. The…”
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