Pituitary apoplexy in association with lymphocytic hypophysitis

Pituitary apoplexy has been recognised much more frequently since the introduction of CT and MRI scanning. Lymphocytic hypophysitis has been increasingly diagnosed in recent years. A case of pituitary apoplexy occurring in a patient with lymphocytic hypophysitis as part of a polyglandular syndrome i...

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Bibliographic Details
Published in:	Journal of clinical neuroscience Vol. 9; no. 5; pp. 577 - 580
Main Authors:	Dan, Noel G., Feiner, Ronald I.D., Houang, Michael T.W., Turner, Jennifer J.
Format:	Journal Article
Language:	English
Published:	Amsterdam Elsevier Ltd 01-09-2002 Elsevier
Subjects:	Adult Biological and medical sciences Cerebral Hemorrhage - etiology Cerebral Hemorrhage - pathology Diabetes Insipidus, Neurogenic - etiology Diabetes Insipidus, Neurogenic - therapy Endocrinopathies Humans Hypopituitarism - etiology Hypopituitarism - therapy Hypothalamus. Hypophysis. Epiphysis (diseases) Inflammation - pathology Lymphocytes - pathology Magnetic Resonance Imaging Male Medical sciences Neurosurgical Procedures Non tumoral diseases. Target tissue resistance. Benign neoplasms Pituitary Apoplexy - complications Pituitary Apoplexy - pathology Pituitary Apoplexy - surgery pituitary apoplexy, lymphocytic hypophysitis, polyglandular syndrome Pituitary Gland, Posterior - pathology pituitary apoplexy, lymphocytic hypophysitis, polyglandular syndrome Endocrinopathy Case study Human Pathology Pituitary diseases Medical imagery Diagnosis Hemorrhage Nuclear magnetic resonance imaging
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Summary:	Pituitary apoplexy has been recognised much more frequently since the introduction of CT and MRI scanning. Lymphocytic hypophysitis has been increasingly diagnosed in recent years. A case of pituitary apoplexy occurring in a patient with lymphocytic hypophysitis as part of a polyglandular syndrome is reported. This combination does not appear to have been previously reported. The pituitary haemorrhage was confirmed on MRI and at surgery. Lymphocytic hypophysitis was confirmed histologically. The apoplexy was accompanied by severe headache, elevation of the optic chiasm, developing field loss and onset of ptosis. The apoplexy was precipitated by neck extension.
Bibliography:	ObjectType-Case Study-2 SourceType-Scholarly Journals-1 ObjectType-Feature-4 content type line 23 ObjectType-Report-1 ObjectType-Article-3
ISSN:	0967-5868 1532-2653
DOI:	10.1054/jocn.2001.0975