Search Results - "Feinbaum, Rhonda"
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Distinct pathogenesis and host responses during infection of C. elegans by P. aeruginosa and S. aureus
Published in PLoS pathogens (01-07-2010)“…The genetically tractable model host Caenorhabditis elegans provides a valuable tool to dissect host-microbe interactions in vivo. Pseudomonas aeruginosa and…”
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Genome-wide identification of Pseudomonas aeruginosa virulence-related genes using a Caenorhabditis elegans infection model
Published in PLoS pathogens (01-07-2012)“…Pseudomonas aeruginosa strain PA14 is an opportunistic human pathogen capable of infecting a wide range of organisms including the nematode Caenorhabditis…”
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The evolutionarily conserved mediator subunit MDT-15/MED15 links protective innate immune responses and xenobiotic detoxification
Published in PLoS pathogens (01-05-2014)“…Metazoans protect themselves from environmental toxins and virulent pathogens through detoxification and immune responses. We previously identified a small…”
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Aberrant Activation of p38 MAP Kinase-Dependent Innate Immune Responses Is Toxic to Caenorhabditis elegans
Published in G3 : genes - genomes - genetics (01-03-2016)“…Inappropriate activation of innate immune responses in intestinal epithelial cells underlies the pathophysiology of inflammatory disorders of the intestine…”
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Tribbles ortholog NIPI-3 and bZIP transcription factor CEBP-1 regulate a Caenorhabditis elegans intestinal immune surveillance pathway
Published in BMC biology (07-12-2016)“…Many pathogens secrete toxins that target key host processes resulting in the activation of immune pathways. The secreted Pseudomonas aeruginosa toxin Exotoxin…”
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Stimulation of host immune defenses by a small molecule protects C. elegans from bacterial infection
Published in PLoS genetics (01-06-2012)“…The nematode Caenorhabditis elegans offers currently untapped potential for carrying out high-throughput, live-animal screens of low molecular weight compound…”
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Trehalose biosynthesis promotes Pseudomonas aeruginosa pathogenicity in plants
Published in PLoS pathogens (01-03-2013)“…Pseudomonas aeruginosa strain PA14 is a multi-host pathogen that infects plants, nematodes, insects, and vertebrates. Many PA14 factors are required for…”
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Genomic analysis reveals that Pseudomonas aeruginosa virulence is combinatorial
Published in Genome biology (12-10-2006)“…Pseudomonas aeruginosa is a ubiquitous environmental bacterium and an important opportunistic human pathogen. Generally, the acquisition of genes in the form…”
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Requirement for a Conserved Toll/Interleukin-1 Resistance Domain Protein in the Caenorhabditis elegans Immune Response
Published in Proceedings of the National Academy of Sciences - PNAS (27-04-2004)“…The p38 mitogen-activated protein kinase pathway regulates innate immune responses in evolutionarily diverse species. We have previously shown that the…”
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The Timing oflin-4RNA Accumulation Controls the Timing of Postembryonic Developmental Events inCaenorhabditis elegans
Published in Developmental biology (01-06-1999)“…Thelin-4gene encodes a small RNA that is required to translationally represslin-14toward the end of the first larval stage ofCaenorhabditis elegansdevelopment…”
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A Conserved p38 MAP Kinase Pathway in Caenorhabditis elegans Innate Immunity
Published in Science (American Association for the Advancement of Science) (26-07-2002)“…A genetic screen for Caenorhabditis elegans mutants with enhanced susceptibility to killing by Pseudomonas aeruginosa led to the identification of two genes…”
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The Evolutionarily Conserved Mediator Subunit MDT-15/MED15 Links Protective Innate Immune Responses and Xenobiotic Detoxification: e1004143
Published in PLoS pathogens (01-05-2014)“…Metazoans protect themselves from environmental toxins and virulent pathogens through detoxification and immune responses. We previously identified a small…”
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The timing of lin-4 RNA accumulation controls the timing of postembryonic developmental events in Caenorhabditis elegans
Published in Developmental biology (01-06-1999)“…The lin-4 gene encodes a small RNA that is required to translationally repress lin-14 toward the end of the first larval stage of Caenorhabditis elegans…”
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The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
Published in Cell (03-12-1993)“…lin-4 is essential for the normal temporal control of diverse postembryonic developmental events in C. elegans. lin-4 acts by negatively regulating the level…”
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Trehalose Biosynthesis Promotes Pseudomonas aeruginosa Pathogenicity in Plants: e1003217
Published in PLoS pathogens (01-03-2013)“…Pseudomonas aeruginosa strain PA14 is a multi-host pathogen that infects plants, nematodes, insects, and vertebrates. Many PA14 factors are required for…”
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Distinct Pathogenesis and Host Responses during Infection of C. elegans by P. aeruginosa and S. aureus: e1000982
Published in PLoS pathogens (01-07-2010)“…The genetically tractable model host Caenorhabditis elegans provides a valuable tool to dissect host-microbe interactions in vivo. Pseudomonas aeruginosa and…”
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Arabidopsis thaliana mutant that develops as a light-grown plant in the absence of light
Published in Cell (08-09-1989)“…The signal transduction pathways that lead to chloroplast biogenesis in plants are largely unknown. We describe here the identification and initial…”
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High intensity and blue light regulated expression of chimeric chalcone synthase genes in transgenic Arabidopsis thaliana plants
Published in Molecular & general genetics (01-05-1991)“…To establish a genetic system for dissection of light-mediated signal transduction in plants, we analyzed the light wavelengths and promoter sequences…”
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Introduction to plasmid biology
Published in Current protocols in molecular biology (Print) (01-05-2001)“…An array of issues pertaining to plasmid biology are presented in this unit. Topics include replicators, an explanation of the mechanism of replication and…”
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