Search Results - "Feijó, Daniel F."
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Resveratrol Reverses Functional Chagas Heart Disease in Mice
Published in PLoS pathogens (01-10-2016)“…Chronic chagasic cardiomyopathy (CCC) develops years after acute infection by Trypanosoma cruzi and does not improve after trypanocidal therapy, despite…”
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Oxidative stress fuels Trypanosoma cruzi infection in mice
Published in The Journal of clinical investigation (01-07-2012)“…Oxidative damage contributes to microbe elimination during macrophage respiratory burst. Nuclear factor, erythroid-derived 2, like 2 (NRF2) orchestrates…”
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Heme oxygenase-1 promotes the persistence of Leishmania chagasi infection
Published in The Journal of immunology (1950) (01-05-2012)“…Visceral leishmaniasis (VL) remains a major public health problem worldwide. This disease is highly associated with chronic inflammation and a lack of the…”
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Decoding the Role of Glycans in Malaria
Published in Frontiers in microbiology (09-06-2017)“…Complications arising from malaria are a concern for public health authorities worldwide, since the annual caseload in humans usually exceeds millions. Of more…”
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Venom alkaloids against Chagas disease parasite: search for effective therapies
Published in Scientific reports (30-06-2020)“…Chagas disease is an important disease affecting millions of patients in the New World and is caused by a protozoan transmitted by haematophagous kissing bugs…”
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MIF participates in Toxoplasma gondii-induced pathology following oral infection
Published in PloS one (22-09-2011)“…Macrophage migration inhibitory factor (MIF) is essential for controlling parasite burden and survival in a model of systemic Toxoplasma gondii infection…”
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Heart function enhancement with Nrf2-activating antioxidant in acute Y-strain Chagas disease, not in chronic Colombian or Y-strain
Published in PLoS neglected tropical diseases (07-11-2024)“…Oxidative stress promotes T . cruzi growth and development of chronic Chagas heart dysfunction. However, the literature contains gaps that must be fulfilled,…”
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