Search Results - "Fei, Mingjian"

Blockade of the Phagocytic Receptor MerTK on Tumor-Associated Macrophages Enhances P2X7R-Dependent STING Activation by Tumor-Derived cGAMP by Zhou, Yi, Fei, Mingjian, Zhang, Gu, Liang, Wei-Ching, Lin, WeiYu, Wu, Yan, Piskol, Robert, Ridgway, John, McNamara, Erin, Huang, Haochu, Zhang, Juan, Oh, Jaehak, Patel, Jaina M., Jakubiak, Diana, Lau, Jeff, Blackwood, Beth, Bravo, Daniel D., Shi, Yongchang, Wang, Jianyong, Hu, Hong-Ming, Lee, Wyne P., Jesudason, Rajiv, Sangaraju, Dewakar, Modrusan, Zora, Anderson, Keith R., Warming, Søren, Roose-Girma, Merone, Yan, Minhong

“…Clearance of apoptotic cells by macrophages prevents excessive inflammation and supports immune tolerance. Here, we examined the effect of blocking apoptotic…”
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Metabolic reprogramming of human CD8 + memory T cells through loss of SIRT1 by Jeng, Mark Y, Hull, Philip A, Fei, Mingjian, Kwon, Hye-Sook, Tsou, Chia-Lin, Kasler, Herb, Ng, Che-Ping, Gordon, David E, Johnson, Jeffrey, Krogan, Nevan, Verdin, Eric, Ott, Melanie

“…The expansion of CD8 CD28 T cells, a population of terminally differentiated memory T cells, is one of the most consistent immunological changes in humans…”
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Cytopathological characteristics of angioimmunoblastic T‐cell lymphoma diagnosed by fine needle aspiration by Fei, Mingjian, Ye, Qiao, Yu, Yawei, Shi, Xianghui, Luo, Fang, Yan, Tingting

“…Objective To analyse the cytopathological features of fine needle aspiration (FNA) in angioimmunoblastic T‐cell lymphoma (AITL) diagnostics. Methods Fine…”
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The Value of Immunocytochemical Staining for the HPV E7 Protein in the Diagnosis of Cervical Lesions by Fei, Mingjian, Yu, Yawei, Hu, Xiaolan, Xu, Haimiao, Liu, Fang

“…To investigate the value of immunocytochemical (ICC) staining for human papillomavirus (HPV) E7 protein (E7-ICC staining) as a new-generation immunological…”
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TNF-α from inflammatory dendritic cells (DCs) regulates lung IL-17A/IL-5 levels and neutrophilia versus eosinophilia during persistent fungal infection by Fei, Mingjian, Bhatia, Shikha, Oriss, Timothy B., Yarlagadda, Manohar, Khare, Anupriya, Akira, Shizuo, Saijo, Shinobu, Iwakura, Yoichiro, Junecko, Beth A. Fallert, Reinhart, Todd A., Foreman, Oded, Ray, Prabir, Kolls, Jay, Ray, Anuradha, Beutler, Bruce

“…Aspergillus fumigatus is commonly associated with allergic bronchopulmonary aspergillosis in patients with severe asthma in which chronic airway neutrophilia…”
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Rapid host defense against Aspergillus fumigatus involves alveolar macrophages with a predominance of alternatively activated phenotype by Bhatia, Shikha, Fei, Mingjian, Yarlagadda, Manohar, Qi, Zengbiao, Akira, Shizuo, Saijo, Shinobu, Iwakura, Yoichiro, van Rooijen, Nico, Gibson, Gregory A, St Croix, Claudette M, Ray, Anuradha, Ray, Prabir

“…The ubiquitous fungus Aspergillus fumigatus is associated with chronic diseases such as invasive pulmonary aspergillosis in immunosuppressed patients and…”
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CLEC5a-directed bispecific antibody for effective cellular phagocytosis by Kedage, Vivekananda, Ellerman, Diego, Fei, Mingjian, Liang, Wei-Ching, Zhang, Gu, Cheng, Eric, Zhang, Juan, Chen, Yongmei, Huang, Haochu, Lee, Wyne P, Wu, Yan, Yan, Minhong

“…While antibody-dependent cellular phagocytosis mediated by activating Fcγ receptor is a key mechanism underlying many antibody drugs, their full therapeutic…”
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Indoleamine 2,3-dioxygenase in lung dendritic cells promotes Th2 responses and allergic inflammation by Xu, Hui, Oriss, Timothy B, Fei, Mingjian, Henry, Adam C, Melgert, Barbro N, Chen, Li, Mellor, Andrew L, Munn, David H, Irvin, Charles G, Ray, Prabir, Ray, Anuradha

“…Indoleamine 2,3 dioxygenase (IDO) has emerged as an important mediator of immune tolerance via inhibition of Th1 responses. However, the role of IDO in…”
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Astilbin inhibits contact hypersensitivity through negative cytokine regulation distinct from cyclosporin A by Fei, Mingjian, Wu, Xuefeng, Xu, Qiang

“…IL-10 is known as a negative regulator for inflammatory diseases, including contact dermatitis. However, only a few drug candidates are reported to induce…”
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Cutting edge: inhaled antigen upregulates retinaldehyde dehydrogenase in lung CD103+ but not plasmacytoid dendritic cells to induce Foxp3 de novo in CD4+ T cells and promote airway tolerance by Khare, Anupriya, Krishnamoorthy, Nandini, Oriss, Timothy B, Fei, Mingjian, Ray, Prabir, Ray, Anuradha

“…Dendritic cell (DC)-T cell interactions that underlie inducible/adaptive regulatory T cell generation and airway tolerance are not well understood. In this…”
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The value of NGS-based multi-gene testing for differentiation of benign from malignant and risk stratification of thyroid nodules by Fei, Mingjian, Ding, Dongdong, Ouyang, Xuanyi, Shen, Wenyan, Zhang, Fenglan, Zhang, Bo, Qin, Lan

“…Background Fine-needle aspiration (FNA) biopsy is typically used in conjunction with cytopathologic evaluation to differentiate between benign and malignant…”
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Activation of c-Kit in dendritic cells regulates T helper cell differentiation and allergic asthma by Paglia, Melissa, Fei, Mingjian, Ray, Anuradha, Krishnamoorthy, Nandini, Yarlagadda, Manohar, Vanhaesebroeck, Bart, Oriss, Timothy B, Ray, Prabir

“…Dendritic cells (DCs) are integral to the differentiation of T helper cells into T helper type 1 T H 1, T H 2 and T H 17 subsets. Interleukin-6 (IL-6) plays an…”
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SIRT1 deacetylates RORγt and enhances Th17 cell generation by Lim, Hyung W, Kang, Seung Goo, Ryu, Jae Kyu, Schilling, Birgit, Fei, Mingjian, Lee, Intelly S, Kehasse, Amanuel, Shirakawa, Kotaro, Yokoyama, Masaru, Schnölzer, Martina, Kasler, Herbert G, Kwon, Hye-Sook, Gibson, Bradford W, Sato, Hironori, Akassoglou, Katerina, Xiao, Changchun, Littman, Dan R, Ott, Melanie, Verdin, Eric

“…The balance of effector and regulatory T cell function, dependent on multiple signals and epigenetic regulators, is critical to immune self-tolerance…”
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IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia by Kreindler, James L, Zheng, Mingquan, McAllister, Florencia, Gaus, Kristi, Aujla, Shean J, Husain, Shahid, Myerburg, Mike M, Iwakura, Yoichiro, Askew, David J, Reinhart, Todd A, Mason, Carol A, Pociask, Derek A, Kolls, Jay K, Fei, Mingjian, Pilewski, Joseph M, Edeal, Jennifer, Dubin, Patricia J, Chan, Yvonne R

“…Emerging evidence supports the concept that T helper type 17 (T H 17) cells, in addition to mediating autoimmunity, have key roles in mucosal immunity against…”
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A Bispecific Modeling Framework Enables the Prediction of Efficacy, Toxicity, and Optimal Molecular Design of Bispecific Antibodies Targeting MerTK by Li, Ran, Dere, Edward, Kwong, Mandy, Fei, Mingjian, Dave, Rutwij, Masih, Shabkhaiz, Wang, Joy, McNamara, Erin, Huang, Haochu, Liang, Wei-Ching, Schutt, Leah, Kamath, Amrita V., Ovacik, Meric A.

“…Inhibiting MerTK on macrophages is a promising therapeutic strategy for augmenting anti-tumor immunity. However, blocking MerTK on retinal pigment epithelial…”
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PEGylation of anti-MerTK Antibody Modulates Ocular Biodistribution by Vollmar, Breanna S., Fei, Mingjian, Liang, Wei-Ching, Bravo, Daniel D., Wang, Joy, Yu, Lanlan, Corr, Nick, Zhang, Gu, McNamara, Erin, Masih, Shabkhaiz, Chee, Elin, Shin, Gawon, Ohri, Rachana, Leipold, Douglas D., Wu, Cong, Dere, Edward, Wang, Jianyong, Huang, Haochu, Wu, Yan, Yan, Minhong

“…Here, we explore whether PEGylation of antibodies can modulate their biodistribution to the eye, an organ once thought to be immune privileged but has recently…”
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miR-196a-2 Promotes Malignant Progression of Thyroid Carcinoma by Targeting NRXN1 by Fan, Yaohua, Fei, MingJian, Li, Yan, Gao, Zhenzhen, Zhu, Yuzhang, Dai, Guiping, Wu, Dongjuan

“…Thyroid cancer (TC) is the most common endocrine malignant disease with a rising morbidity year by year. Accumulating studies have shown that microRNAs…”
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Disruption of chaperone-mediated autophagy-dependent degradation of MEF2A by oxidative stress-induced lysosome destabilization by Zhang, Li, Sun, Yang, Fei, Mingjian, Tan, Cheng, Wu, Jing, Zheng, Jie, Tang, Jiqing, Sun, Wei, Lv, Zhaoliang, Bao, Jiandong, Xu, Qiang, Yu, Huixin

“…Oxidative stress has been implicated in both normal aging and various neurodegenerative disorders and it may be a major cause of neuronal death…”
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Diagnostic Significance of Ultrasound-Guided Fine-Needle Aspiration Biopsy and on-Site Assessment by Pathologists for Thyroid Micronodules by Fei, Mingjian, Zhang, Fenglan, Qin, Lan, Zheng, Xueyong, Zhang, Bo, Ouyang, Xuanyi

“…Ultrasound-guided fine-needle aspiration biopsy (US-FNAB) is a safe and effective method for screening malignant thyroid nodules. The purpose of this study was…”
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Inhaled Antigen Upregulates Retinaldehyde Dehydrogenase In Lung CD103+ But Not Plasmacytoid Dendritic Cells To Induce Foxp3 De Novo in CD4+ T cells and Promote Airway Tolerance by Khare, Anupriya, Krishnamoorthy, Nandini, Oriss, Timothy B., Fei, Mingjian, Ray, Prabir, Ray, Anuradha

“…Dendritic cell (DC)-T cell interactions that underlie iTreg generation and airway tolerance are not well understood. Here we show that mice lacking CD11c hi…”
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