Search Results - "Fei, Guoqiang"

Identification of diagnostic biomarkers in Alzheimer's disease by integrated bioinformatic analysis and machine learning strategies by Jin, Boru, Cheng, Xiaoqin, Fei, Guoqiang, Sang, Shaoming, Zhong, Chunjiu

“…Alzheimer's disease (AD) is the most prevalent form of dementia, and is becoming one of the most burdening and lethal diseases. More useful biomarkers for…”
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Identification of biomarkers differentiating Alzheimer's disease from other neurodegenerative diseases by integrated bioinformatic analysis and machine-learning strategies by Jin, Boru, Fei, Guoqiang, Sang, Shaoming, Zhong, Chunjiu

“…Alzheimer's disease (AD) is the most common neurodegenerative disease, imposing huge mental and economic burdens on patients and society. The specific…”
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Recombinant vaccine containing an RBD-Fc fusion induced protection against SARS-CoV-2 in nonhuman primates and mice by Sun, Shihui, He, Lei, Zhao, Zhongpeng, Gu, Hongjing, Fang, Xin, Wang, Tiecheng, Yang, Xiaolan, Chen, Shaolong, Deng, Yongqiang, Li, Jiangfan, Zhao, Jian, Li, Liang, Li, Xinwang, He, Peng, Li, Ge, Li, Hao, Zhao, Yuee, Gao, Chunrun, Lang, Xiaoling, Wang, Xin, Fei, Guoqiang, Li, Yan, Geng, Shusheng, Gao, Yuwei, Wei, Wenjin, Hu, Zhongyu, Han, Gencheng, Sun, Yansong

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A comparison of the five-minute cognitive test with the mini-mental state examination in the elderly for cognitive impairment screening by Pan, Xiaoli, Cheng, Xiaoqin, Zhang, Jie, Xia, Yingfeng, Zhong, Chunjiu, Fei, Guoqiang

“…The five-minute cognitive test (FCT) is a novel cognitive screening method with the quick and reliable merit for detecting cognitive impairment at an early…”
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Decreased serum ceruloplasmin levels characteristically aggravate nigral iron deposition in Parkinson's disease by Jin, Lirong, Wang, Jian, Zhao, Lei, Jin, Hang, Fei, Guoqiang, Zhang, Yuwen, Zeng, Mengsu, Zhong, Chunjiu

“…In vivo and post-mortem studies have demonstrated that increased nigral iron content in patients with Parkinson's disease is a prominent pathophysiological…”
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Neuromelanin-sensitive MRI of the substantia nigra: An imaging biomarker to differentiate essential tremor from tremor-dominant Parkinson's disease by Wang, Jian, Huang, Zhen, Li, Yuanfang, Ye, Fang, Wang, Changpeng, Zhang, Yong, Cheng, Xiaoqin, Fei, Guoqiang, Liu, Kai, Zeng, Mengsu, Zhong, Chunjiu, Jin, Lirong

“…We aimed to evaluate whether neuromelanin-sensitive MRI (NM-MRI) features in the substantia nigra pars compacta (SNc) were of diagnostic value to differentiate…”
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Combined Visualization of Nigrosome-1 and Neuromelanin in the Substantia Nigra Using 3T MRI for the Differential Diagnosis of Essential Tremor and de novo Parkinson's Disease by Jin, Lirong, Wang, Jian, Wang, Changpeng, Lian, Danlan, Zhou, Ying, Zhang, Yong, Lv, Minzhi, Li, Yuanfang, Huang, Zhen, Cheng, Xiaoqin, Fei, Guoqiang, Liu, Kai, Zeng, Mengsu, Zhong, Chunjiu

“…Differentiating early-stage Parkinson's disease (PD) from essential tremor (ET) remains challenging. In the current study, we aimed to evaluate whether visual…”
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Enhanced Activities of Blood Thiamine Diphosphatase and Monophosphatase in Alzheimer's Disease by Pan, Xiaoli, Sang, Shaoming, Fei, Guoqiang, Jin, Lirong, Liu, Huimin, Wang, Zhiliang, Wang, Hui, Zhong, Chunjiu

“…Thiamine metabolites and activities of thiamine-dependent enzymes are impaired in Alzheimer's disease (AD). To clarify the mechanism for the reduction of…”
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Sleep Duration Positively Correlates with Global Cognition in the Non-Demented Older Adults with High School or above Education by Deng, Xia, Pan, Xiaoli, Cheng, Xiaoqin, Zhang, Jie, Wang, Lijun, Sang, Shaoming, Zhong, Chunjiu, Fei, Guoqiang

“…BACKGROUNDSleep disturbance is common in the elderly. The effect of sleep duration on cognitive function in the non-demented older adults with high school or…”
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Acute Respiratory Failure Is the Initial Manifestation in the Adult-Onset A3243G tRNALeu mtDNA Mutation: A Case Report and the Literature Review by Pan, Xiaoli, Wang, Lijun, Fei, Guoqiang, Dong, Jihong, Zhong, Chunjiu, Lu, Jiahong, Jin, Lirong

“…Isolated mitochondrial myopathy refers to the condition of mitochondrial disorders that primarily affect the skeletal muscle system. Here we report on a case…”
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Thiamine diphosphate reduction strongly correlates with brain glucose hypometabolism in Alzheimer's disease, whereas amyloid deposition does not by Sang, Shaoming, Pan, Xiaoli, Chen, Zhichun, Zeng, Fan, Pan, Shumei, Liu, Huimin, Jin, Lirong, Fei, Guoqiang, Wang, Changpeng, Ren, Shuhua, Jiao, Fangyang, Bao, Weiqi, Zhou, Weiyan, Guan, Yihui, Zhang, Yiqiu, Shi, Hongcheng, Wang, Yanjiang, Yu, Xiang, Wang, Yun, Zhong, Chunjiu

“…The underlying mechanism of brain glucose hypometabolism, an invariant neurodegenerative feature that tightly correlates with cognitive impairment and disease…”
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Association Between Blood Biochemical Factors Contributing to Cognitive Decline and B Vitamins in Patients With Alzheimer's Disease by Qian, Ting, Zhao, Lei, Pan, Xiaoli, Sang, Shaoming, Xu, Yangqi, Wang, Changpeng, Zhong, Chunjiu, Fei, Guoqiang, Cheng, Xiaoqin

“…Malnutrition, metabolism stress, inflammation, peripheral organs dysfunction, and B vitamins deficiency significantly contribute to the progression and…”
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Measurement of Blood Thiamine Metabolites for Alzheimer's Disease Diagnosis by Pan, Xiaoli, Fei, Guoqiang, Lu, Jingwen, Jin, Lirong, Pan, Shumei, Chen, Zhichun, Wang, Changpeng, Sang, Shaoming, Liu, Huimin, Hu, Weihong, Zhang, Hua, Wang, Hui, Wang, Zhiliang, Tan, Qiong, Qin, Yan, Zhang, Qunying, Xie, Xueping, Ji, Yong, Cui, Donghong, Gu, Xiaohua, Xu, Jun, Yu, Yuguo, Zhong, Chunjiu

“…Brain glucose hypometabolism is an invariant feature and has significant diagnostic value for Alzheimer's disease. Thiamine diphosphate (TDP) is a critical…”
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Decreased Function of Delayed Recall in Non-demented Elderly Subjects With Apolipoprotein E ε4 Allele by Wang, Lijun, Pan, Xiaoli, Fei, Guoqiang, Wang, Changpeng, Wan, Wenbin, Sang, Shaoming, Wang, Hui, Wang, Zhiliang, Zhong, Chunjiu

“…Apolipoprotein E (APOE) is the major genetic risk factor for late-onset Alzheimer's disease (AD). Inconsistent results about the role of APOE ε4 alleles on…”
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A randomized, double‐blind, placebo‐controlled phase 1 and phase 2 clinical trial to evaluate efficacy and safety of a SARS‐CoV‐2 vaccine SCoK in adults by Luo, Deyan, Pan, Hongxing, He, Peng, Yang, Xiaolan, Li, Tao, Ning, Nianzhi, Fang, Xin, Yu, Wenjing, Wei, Mingwei, Gao, Hui, Wang, Xin, Gu, Hongjing, Mei, Maodong, Li, Xinwang, Zhang, Liangyan, Li, Deyu, Gao, Chunrun, Gao, Jinbang, Fei, Guoqiang, Li, Ying, Yang, Yuguo, Xu, Yi, Wei, Wenjin, Sun, Yansong, Zhu, Fengcai, Hu, Zhongyu, Wang, Hui

“…Background To determine an appropriate dose of, and immunization schedule for, a vaccine SCoK against COVID‐19 for an efficacy study; herein, we conducted…”
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MR Imaging of Nonalcoholic Wernicke Encephalopathy: A Follow-Up Study by Zhong, Chunjiu, Jin, Lirong, Fei, Guoqiang

“…We investigated the correlation of MR imaging features with the pathological evolution and prognosis of nonalcoholic Wernicke encephalopathy. A retrospective…”
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Correlation of thiamine metabolite levels with cognitive function in the non-demented elderly by Lu, Jingwen, Pan, Xiaoli, Fei, Guoqiang, Wang, Changpeng, Zhao, Lei, Sang, Shaoming, Liu, Huimin, Liu, Meng, Wang, Hui, Wang, Zhiliang, Zhong, Chunjiu

“…Thiamine metabolism is critical for glucose metabolism and also vital for brain function, which is susceptible to decline in the elderly. This study aimed to…”
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Low expression of thiamine pyrophosphokinase-1 contributes to brain susceptibility to thiamine deficiency by Xia, Yingfeng, Qian, Ting, Fei, Guoqiang, Cheng, Xiaoqin, Zhao, Lei, Sang, Shaoming, Zhong, Chunjiu

“…Thiamine deficiency is a well-known risk factor for the development of severe encephalopathy, such as Wernicke encephalopathy and Korsakoff syndrome, but the…”
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Decreased serum ceruloplasmin levels characteristically aggravate nigral iron deposition in Parkinson’s disease by Jin, Lirong, Wang, Jian, Zhao, Lei, Jin, Hang, Fei, Guoqiang, Zhang, Yuwen, Zeng, Mengsu, Zhong, Chunjiu

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Metabolomic Characterization of Acute Ischemic Stroke Facilitates Metabolomic Biomarker Discovery by Qi, Biao, Zhang, Yanyu, Xu, Bing, Zhang, Yuhao, Fei, Guoqiang, Lin, Ling, Li, Qiuping

“…Acute ischemic stroke (AIS) is characterized by a sudden blockage of one of the main arteries supplying blood to the brain, leading to insufficient oxygen and…”
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