Search Results - "Fehling, Sarah K."
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Acidic pH-Induced Conformations and LAMP1 Binding of the Lassa Virus Glycoprotein Spike
Published in PLoS pathogens (05-02-2016)“…Lassa virus is an enveloped, bi-segmented RNA virus and the most prevalent and fatal of all Old World arenaviruses. Virus entry into the host cell is mediated…”
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Serological Evidence for the Circulation of Ebolaviruses in Pigs From Sierra Leone
Published in The Journal of infectious diseases (22-11-2018)“…Many human ebolavirus outbreaks have been linked to contact with wildlife including nonhuman primates and bats, which are assumed to serve as host species…”
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Detectable Vesicular Stomatitis Virus (VSV)–Specific Humoral and Cellular Immune Responses Following VSV–Ebola Virus Vaccination in Humans
Published in The Journal of infectious diseases (29-01-2019)“…This study investigates preexisting and vaccine-induced vector immunity in 30 participants of a Phase-1 VSV-EBOV Ebola vaccine trial. No preexisting immunity…”
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4
Development of a Cost-effective Ovine Polyclonal Antibody-Based Product, EBOTAb, to Treat Ebola Virus Infection
Published in The Journal of infectious diseases (01-04-2016)“…The highly glycosylated glycoprotein spike of Ebola virus (EBOV-GP1,2) is the primary target of the humoral host response. Recombinant EBOV-GP ectodomain…”
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Randomized, Blinded, Dose-Ranging Trial of an Ebola Virus Glycoprotein Nanoparticle Vaccine With Matrix-M Adjuvant in Healthy Adults
Published in The Journal of infectious diseases (23-07-2020)“…Abstract Background Ebola virus (EBOV) epidemics pose a major public health risk. There currently is no licensed human vaccine against EBOV. The safety and…”
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Comprehensive Characterization of Cellular Immune Responses Following Ebola Virus Infection
Published in The Journal of infectious diseases (15-01-2017)“…The West African Ebola virus disease (EVD) outbreak was the largest EVD outbreak in history. However, data on lymphocyte dynamics and the antigen specificity…”
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Serological evidence of exposure to ebolaviruses in domestic pigs from Guinea
Published in Transboundary and emerging diseases (01-03-2020)“…The genus Ebolavirus comprises several virus species with zoonotic potential and varying pathogenicity for humans. Ebolaviruses are considered to circulate in…”
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Proteomic landscape of SARS-CoV-2- and MERS-CoV-infected primary human renal epithelial cells
Published in Life science alliance (01-05-2022)“…Acute kidney injury is associated with mortality in COVID-19 patients. However, host cell changes underlying infection of renal cells with SARS-CoV-2 remain…”
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Phase 1 Trials of rVSV Ebola Vaccine in Africa and Europe
Published in The New England journal of medicine (28-04-2016)“…In this set of four phase 1 studies, a recombinant vesicular stomatitis virus (rVSV)–based Ebola vaccine induced Ebola virus–specific immune responses and was…”
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Acidic pH-Induced Conformations and LAMP1 Binding of the Lassa Virus Glycoprotein Spike: e1005418
Published in PLoS pathogens (01-02-2016)“…Lassa virus is an enveloped, bi-segmented RNA virus and the most prevalent and fatal of all Old World arenaviruses. Virus entry into the host cell is mediated…”
Get full text
Journal Article -
11
Dose-dependent T-cell Dynamics and Cytokine Cascade Following rVSV-ZEBOV Immunization
Published in EBioMedicine (01-05-2017)“…The recent West African Ebola epidemic led to accelerated efforts to test Ebola vaccine candidates. As part of the World Health Organisation-led VSV Ebola…”
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