Search Results - "Feeney, Eoin R"

HCV and HIV co-infection: mechanisms and management by Chen, Jennifer Y., Feeney, Eoin R., Chung, Raymond T.

“…Key Points Patients co-infected with HCV and HIV are at increased risk of accelerated disease progression, resulting in higher rates of liver decompensation…”
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Distinct receptor binding domain IgG thresholds predict protective host immunity across SARS-CoV-2 variants and time by Kenny, Grace, O’Reilly, Sophie, Wrigley Kelly, Neil, Negi, Riya, Gaillard, Colette, Alalwan, Dana, Saini, Gurvin, Alrawahneh, Tamara, Francois, Nathan, Angeliadis, Matthew, Garcia Leon, Alejandro Abner, Tinago, Willard, Feeney, Eoin R., Cotter, Aoife G., de Barra, Eoghan, Yousif, Obada, Horgan, Mary, Doran, Peter, Stemler, Jannik, Koehler, Philipp, Cox, Rebecca Jane, O’Shea, Donal, Olesen, Ole F., Landay, Alan, Hogan, Andrew E., Lelievre, Jean-Daniel, Gautier, Virginie, Cornely, Oliver A., Mallon, Patrick W. G.

“…SARS-CoV-2 neutralising antibodies provide protection against COVID-19. Evidence from early vaccine trials suggested binding antibody thresholds could serve as…”
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Development of a novel medium throughput flow-cytometry based micro-neutralisation test for SARS-CoV-2 with applications in clinical vaccine trials and antibody screening by O'Reilly, Sophie, Kenny, Grace, Alrawahneh, Tamara, Francois, Nathan, Gu, Lili, Angeliadis, Matthew, de Masson d'Autume, Valentin, Garcia Leon, Alejandro, Feeney, Eoin R, Yousif, Obada, Cotter, Aoife, de Barra, Eoghan, Horgan, Mary, Mallon, Patrick W. G, Gautier, Virginie

“…Quantifying neutralising capacity of circulating SARS-COV-2 antibodies is critical in evaluating protective humoral immune responses generated…”
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Impact of mitochondrial toxicity of HIV-1 antiretroviral drugs on lipodystrophy and metabolic dysregulation by Feeney, Eoin R, Mallon, Patrick W G

“…Nucleoside reverse transcriptase inhibitors (NRTIs) are components of most current antiretroviral (ARV) regimens. Side effects arising from mitochondrial…”
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Identification of Distinct Long COVID Clinical Phenotypes Through Cluster Analysis of Self-Reported Symptoms by Kenny, Grace, McCann, Kathleen, O’Brien, Conor, Savinelli, Stefano, Tinago, Willard, Yousif, Obada, Lambert, John S, O’Broin, Cathal, Feeney, Eoin R, De Barra, Eoghan, Doran, Peter, Mallon, Patrick W G

“…Abstract Background We aimed to describe the clinical presentation of individuals presenting with prolonged recovery from coronavirus disease 2019 (COVID-19),…”
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Impact of vaccination and variants of concern on long COVID clinical phenotypes by Kenny, Grace, McCann, Kathleen, O'Brien, Conor, O'Broin, Cathal, Tinago, Willard, Yousif, Obada, O'Gorman, Tessa, Cotter, Aoife G, Lambert, John S, Feeney, Eoin R, de Barra, Eoghan, Sadlier, Corinna, Landay, Alan, Doran, Peter, Savinelli, Stefano, Mallon, Patrick W. G, MacCann, Rachel, Garcia Leon, Alejandro, Miles, Sarah, Alalwan, Dana, Negi, Riya, Muldoon, Eavan, Sheehan, Gerard, McGinty, Tara, Green, Sandra, Leamy, Kelly, Kelly, Christine, de Barra, Eoin, McConkey, Samuel, Hurley, Killain, Sulaiman, Imran, Horgan, Mary, Eustace, Joseph, Bracken, Tommy, Whelan, Bryan, Low, Justin, McNicholas, Bairbre, Courtney, Garry, Gavin, Patrick

“…Abstract Background Defining patterns of symptoms in long COVID is necessary to advance therapies for this heterogeneous condition. Here we aimed to describe…”
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Dysregulated early transcriptional signatures linked to mast cell and interferon responses are implicated in COVID-19 severity by MacCann, Rachel, Leon, Alejandro Abner Garcia, Gonzalez, Gabriel, Carr, Michael J, Feeney, Eoin R, Yousif, Obada, Cotter, Aoife G, de Barra, Eoghan, Sadlier, Corinna, Doran, Peter, Mallon, Patrick W

“…Dysregulated immune responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are thought to underlie the progression of coronavirus…”
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Navigating the Landscape of B Cell Mediated Immunity and Antibody Monitoring in SARS-CoV-2 Vaccine Efficacy: Tools, Strategies and Clinical Trial Insights by O'Reilly, Sophie, Byrne, Joanne, Feeney, Eoin R, Mallon, Patrick W G, Gautier, Virginie

“…Correlates of Protection (CoP) are biomarkers above a defined threshold that can replace clinical outcomes as primary endpoints, predicting vaccine…”
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Early inflammatory profiles predict maximal disease severity in COVID-19: An unsupervised cluster analysis by Kenny, Grace, Saini, Gurvin, Gaillard, Colette Marie, Negi, Riya, Alalwan, Dana, Garcia Leon, Alejandro, McCann, Kathleen, Tinago, Willard, Kelly, Christine, Cotter, Aoife G., de Barra, Eoghan, Horgan, Mary, Yousif, Obada, Gautier, Virginie, Landay, Alan, McAuley, Danny, Feeney, Eoin R., O'Kane, Cecilia, Mallon, Patrick WG

“…The inflammatory changes that underlie the heterogeneous presentations of COVID-19 remain incompletely understood. In this study we aimed to identify…”
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Chronotropic incompetence in HIV infection by Feeney, Eoin R, Boix, Vicente, Hsue, Priscilla Y

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Remote monitoring of oxygen saturation in individuals with COVID-19 pneumonia by O'Carroll, Orla, MacCann, Rachel, O'Reilly, Aoife, Dunican, Eleanor M, Feeney, Eoin R, Ryan, Silke, Cotter, Aoife, Mallon, Patrick W, Keane, Michael P, Butler, Marcus W, McCarthy, Cormac

“…Coronavirus disease 2019 (COVID-19), an illness caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, has spread rapidly worldwide,…”
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Prevalence of comorbid asthma in COVID-19 patients by Butler, Marcus W., O’Reilly, Aoife, Dunican, Eleanor M., Mallon, Patrick, Feeney, Eoin R., Keane, Michael P., McCarthy, Cormac

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Antiviral treatment of hepatitis C by Feeney, Eoin R, Chung, Raymond T

“…Hepatitis C virus (HCV) infection is a substantial health problem worldwide. Most patients infected with HCV remain chronically infected, with an increased…”
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Obesity is associated with higher levels of circulating cytokines involved in the development of cardiovascular disease in people living with HIV by Savinelli, Stefano, McGettrick, Pádraig, Garcia Leon, Alejandro A, Tinago, Willard, Haran, Emma, Barco, Elena Alvarez, Landay, Alan L, Mallon, Patrick Wg, Feeney, Eoin R

“…Obesity is increasingly described in people living with HIV (PLWH), but its impact on immune activation and inflammation in HIV is still poorly characterised…”
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Chronic hepatitis C infection–induced liver fibrogenesis is associated with M2 macrophage activation by Bility, Moses T., Nio, Kouki, Li, Feng, McGivern, David R., Lemon, Stanley M., Feeney, Eoin R., Chung, Raymond T., Su, Lishan

“…The immuno-pathogenic mechanisms of chronic hepatitis C virus (HCV) infection remain to be elucidated and pose a major hurdle in treating or preventing chronic…”
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Associations between host microbiome and inflammation suggest role for host microbiome in driving COVID-19 disease severity by MacCann, Rachel, Ghosh, Tarini Shankar, Garcia Leon, Alejandro Abner, Li, Junhui, Negi, Riya, Gaillard, Colette, Saini, Gurvin, Tinago, Willard, Feeney, Eoin R., Yousif, Obada, Cotter, Aoife G., de Barra, Eoghan, Sadlier, Corinna, Doran, Peter, Landay, Alan, O'Toole, Paul W., Mallon, Patrick W.

“…Systemic inflammation and innate immune activation are associated with COVID-19 disease severity. Knowledge gaps remain in the relationships between…”
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Performance and validation of an adaptable multiplex assay for detection of serologic response to SARS-CoV-2 infection or vaccination by Kenny, Grace, Negi, Riya, O'Reilly, Sophie, Garcia-Leon, Alejandro, Alalwan, Dana, Gaillard, Colette Marie, Saini, Gurvin, Inzitari, Rosana, Feeney, Eoin R., Yousif, Obada, Cotter, Aoife G, de Barra, Eoghan, Sadlier, Corinna, Crispie, Fiona, Doran, Peter, Gautier, Virginie, Mallon, Patrick W.G.

“…Measurement of quantitative antibody responses are increasingly important in evaluating the immune response to infection and vaccination. In this study we…”
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Macrophage Activation Marker Soluble CD163 Is a Dynamic Marker of Liver Fibrogenesis in Human Immunodeficiency Virus/Hepatitis C Virus Coinfection by Lidofsky, Anna, Holmes, Jacinta A, Feeney, Eoin R, Kruger, Annie J, Salloum, Shadi, Zheng, Hui, Seguin, Isabel S, Altinbas, Akif, Masia, Ricard, Corey, Kathleen E, Gustafson, Jenna L, Schaefer, Esperance A, Hunt, Peter W, Deeks, Steven, Somsouk, Ma, Chew, Kara W, Chung, Raymond T, Alatrakchi, Nadia

“…Coinfection with human immunodeficiency virus (HIV) accelerates hepatitis C virus (HCV)-related liver fibrosis. Macrophages are triggered during both viral…”
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Obesity in HIV infection: host-pathogen interaction by Savinelli, Stefano, Wrigley Kelly, Neil E., Feeney, Eoin R., O'Shea, Donal B., Hogan, Andrew E., Overton, Edgar T., Landay, Alan L., Mallon, Patrick W.

“…Both obesity and HIV infection are characterized by a state of chronic inflammation associated with increased morbidity and mortality. This review aims to…”
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Prediction of low pulse oxygen saturation in COVID-19 using remote monitoring post hospital discharge by Doheny, Emer P., Flood, Matthew, Ryan, Silke, McCarthy, Cormac, O'Carroll, Orla, O'Seaghdha, Conall, Mallon, Patrick W., Feeney, Eoin R., Keatings, Vera M., Wilson, Moya, Kennedy, Niall, Gannon, Avril, Edwards, Colin, Lowery, Madeleine M.

“…•SpO2, heart rate and breathlessness post hospital discharge in COVID-19 are examined.•Age and sex did not affect symptom presentation during low SpO2 in…”
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