Search Results - "Fee, Conan"
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Numerical Elucidation of Flow and Dispersion in Ordered Packed Beds: Nonspherical Polygons and the Effect of Particle Overlap on Chromatographic Performance
Published in Analytical chemistry (Washington) (03-12-2019)“…Spherical particles are widely considered as the benchmark stationary phase for preparative and analytical chromatography. Although this has proven true for…”
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GMA‐based emulsion‐templated solid foams: Influence of co‐crosslinker on morphology and mechanical properties
Published in Journal of applied polymer science (05-06-2018)“…ABSTRACT Highly open porous polymer foams formed from high internal phase emulsions (polyHIPEs) are attracting significant interest because of their potential…”
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Size comparison between proteins PEGylated with branched and linear poly(ethylene glycol) molecules
Published in Biotechnology and bioengineering (01-11-2007)“…Therapeutic proteins conjugated with branched poly(ethylene glycol) (PEG) have extended in vivo circulation half-lives compared to linear PEG-proteins, thought…”
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A numerical investigation of the hydrodynamic dispersion in triply periodic chromatographic stationary phases
Published in Journal of Chromatography A (06-12-2022)“…•Permeability of triply periodic monoliths is lower than packed spheres and open channels.•Schwarz diamond monoliths have low hydrodynamic dispersion.•Open…”
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Mixed matrix membrane chromatography based on hydrophobic interaction for whey protein fractionation
Published in Journal of membrane science (01-10-2013)“…The mixed matrix membrane (MMM) concept is extended, for the first time, to produce a hydrophobic interaction chromatography (HIC) membrane using crushed…”
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Reversible and Rapid pH-Regulated Self-Assembly of a Poly(ethylene glycol)–Peptide Bioconjugate
Published in Langmuir (02-12-2014)“…The use of external triggers to manipulate the secondary structure of self-assembling peptides conjugated to flexible synthetic polymers is a challenging…”
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Analysis of the Effect of Processing Conditions on Physical Properties of Thermally Set Cellulose Hydrogels
Published in Materials (01-04-2019)“…Cellulose-based hydrogels were prepared by dissolving cellulose in aqueous sodium hydroxide (NaOH)/urea solutions and casting it into complex shapes by the use…”
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Effects of PEG size on structure, function and stability of PEGylated BSA
Published in European journal of pharmaceutics and biopharmaceutics (01-10-2011)“…The binding of surfactant, SDS, to BSA appears to be altered upon PEGylation, as two distinct classes of binding sites (high and low affinity) for BSA and one…”
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Study of the adsorption of proteins on stainless steel surfaces using QCM-D
Published in Chemical engineering research & design (01-09-2013)“…•Reversible and irreversible protein adsorption was found in most cases.•Relationship between protein adsorbed to molecular weight of the protein.•Relationship…”
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Label-free, real-time interaction and adsorption analysis 1: surface plasmon resonance
Published in Methods in molecular biology (Clifton, N.J.) (2013)“…A key requirement for the development of proteins for use in nanotechnology is an understanding of how individual proteins bind to other molecules as they…”
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PEG-proteins: Reaction engineering and separation issues
Published in Chemical engineering science (01-02-2006)“…Poly(ethylene glycol)-conjugated (or PEGylated) proteins are an increasingly important class of therapeutic proteins that offer improved in vivo circulation…”
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Conformational Studies of Covalently Grafted Poly(ethylene glycol) on Modified Solid Matrices Using X-ray Photoelectron Spectroscopy
Published in Langmuir (18-05-2010)“…Amine functionalized poly(ethylene glycols) (PEGs) with molecular weights 2000 and 4000 Da were covalently grafted onto carboxy modified hydrophilic Sephadex…”
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Label-free, real-time interaction and adsorption analysis 2: quartz crystal microbalance
Published in Methods in molecular biology (Clifton, N.J.) (2013)“…In this chapter, a second biosensor technique is described: the quartz crystal microbalance (QCM). The quartz crystal microbalance is a physical technique that…”
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Evaluation of Biopolymer Materials and Synthesis Techniques to Develop a Rod-Shaped Biopolymer Surrogate for Legionella pneumophila
Published in Polymers (24-06-2022)“…Biopolymer microparticles have been developed for applications that require biocompatibility and biodegradability, such as drug delivery. In this study, we…”
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Molecular basis of a redox switch: molecular dynamics simulations and surface plasmon resonance provide insight into reduced and oxidised angiotensinogen
Published in Biochemical journal (17-09-2021)“…Angiotensinogen fine-tunes the tightly controlled activity of the renin-angiotensin system by modulating the release of angiotensin peptides that control blood…”
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Simultaneous anion and cation exchange chromatography of whey proteins using a customizable mixed matrix membrane
Published in Journal of Chromatography A (16-12-2011)“…► We develop mixed mode interaction in single membrane chromatography. ► This membrane performs based on cation and anion exchanger functionalities. ► Mixed…”
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Corticosteroid-binding globulin (CBG) reactive centre loop antibodies and surface plasmon resonance interrogate the proposed heat dependent “flip-flop” mechanism of human CBG
Published in The Journal of steroid biochemistry and molecular biology (01-04-2016)“…•We interrogate the proposed heat dependent “flip-flop” of the reactive centre loop (RCL) of human CBG using antibodies and surface plasmon resonance.•These…”
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Recovery of lactoferrin from whey using cross-flow cation exchange mixed matrix membrane chromatography
Published in Separation and purification technology (02-02-2011)“…[Display omitted] ▶ Adsorption of lysozyme onto the embedded resin was visualized by CLSM. ▶ Static LF binding capacity of the SP Sepharose MMM was 384 mg g…”
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Surface-Modified Biopolymer Microparticles: A Potential Surrogate for Studying Legionella pneumophila Attachment to Biofilms in Engineered Water Systems
Published in ACS ES&T water (10-09-2021)“…Despite numerous legionellosis outbreaks attributed to contaminated engineered water systems (EWSs), no suitable surrogate has been established for studying…”
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