Search Results - "Fedosov, Dmitry A."

Margination of micro- and nano-particles in blood flow and its effect on drug delivery by Müller, Kathrin, Fedosov, Dmitry A., Gompper, Gerhard

“…Drug delivery by micro- and nano-carriers enables controlled transport of pharmaceuticals to targeted sites. Even though carrier fabrication has made much…”
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Flow-Induced Transitions of Red Blood Cell Shapes under Shear by Mauer, Johannes, Mendez, Simon, Lanotte, Luca, Nicoud, Franck, Abkarian, Manouk, Gompper, Gerhard, Fedosov, Dmitry A

“…A recent study of red blood cells (RBCs) in shear flow [Lanotte et al., Proc. Natl. Acad. Sci. U.S.A. 113, 13289 (2016)PNASA60027-842410.1073/pnas.1608074113]…”
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Deformation and dynamics of red blood cells in flow through cylindrical microchannels by Fedosov, Dmitry A, Peltomäki, Matti, Gompper, Gerhard

“…The motion of red blood cells (RBCs) in microcirculation plays an important role in blood flow resistance and in the cell partitioning within a microvascular…”
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Multiscale modeling of blood flow: from single cells to blood rheology by Fedosov, Dmitry A., Noguchi, Hiroshi, Gompper, Gerhard

“…Mesoscale simulations of blood flow, where the red blood cells are described as deformable closed shells with a membrane characterized by bending rigidity and…”
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White blood cell margination in microcirculation by Fedosov, Dmitry A, Gompper, Gerhard

“…Proper functioning of white blood cells is not possible without their ability to adhere to vascular endothelium, which may occur only if they are close enough…”
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Red cells’ dynamic morphologies govern blood shear thinning under microcirculatory flow conditions by Lanotte, Luca, Mauer, Johannes, Mendez, Simon, Fedosov, Dmitry A., Fromental, Jean-Marc, Claveria, Viviana, Nicoud, Franck, Gompper, Gerhard, Abkarian, Manouk

“…Blood viscosity decreases with shear stress, a property essential for an efficient perfusion of the vascular tree. Shear thinning is intimately related to the…”
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Hydrodynamic clustering of two finite-length flagellated swimmers in viscoelastic fluids by Mo, Chaojie, Fedosov, Dmitry A

“…Clustering of flagellated microswimmers such as sperm is often mediated by hydrodynamic interactions between them. To better understand the interaction of…”
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Deterministic Lateral Displacement: Challenges and Perspectives by Hochstetter, Axel, Vernekar, Rohan, Austin, Robert H, Becker, Holger, Beech, Jason P, Fedosov, Dmitry A, Gompper, Gerhard, Kim, Sung-Cheol, Smith, Joshua T, Stolovitzky, Gustavo, Tegenfeldt, Jonas O, Wunsch, Benjamin H, Zeming, Kerwin K, Krüger, Timm, Inglis, David W

“…The advent of microfluidics in the 1990s promised a revolution in multiple industries from healthcare to chemical processing. Deterministic lateral…”
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Predicting human blood viscosity in silico by Fedosov, Dmitry A, Pan, Wenxiao, Caswell, Bruce, Gompper, Gerhard, Karniadakis, George E

“…The viscosity of blood has long been used as an indicator in the understanding and treatment of disease, and the advent of modern viscometers allows its…”
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Microvascular blood flow resistance: Role of red blood cell migration and dispersion by Katanov, Dinar, Gompper, Gerhard, Fedosov, Dmitry A.

“…Microvascular blood flow resistance has a strong impact on cardiovascular function and tissue perfusion. The flow resistance in microcirculation is governed by…”
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Systematic coarse-graining of spectrin-level red blood cell models by Fedosov, Dmitry A., Caswell, Bruce, Karniadakis, George Em

“…We present a rigorous procedure to derive coarse-grained red blood cell (RBC) models, which yield accurate mechanical response. Based on a semi-analytic theory…”
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Margination of white blood cells in microcapillary flow by Fedosov, Dmitry A, Fornleitner, Julia, Gompper, Gerhard

“…Margination of white blood cells (WBCs) towards vessel walls is an essential precondition for their efficient adhesion to the vascular endothelium. We perform…”
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Static and dynamic properties of smoothed dissipative particle dynamics by Alizadehrad, Davod, Fedosov, Dmitry A.

“…In this paper, static and dynamic properties of the smoothed dissipative particle dynamics (SDPD) method are investigated. We study the effect of method…”
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Margination and stretching of von Willebrand factor in the blood stream enable adhesion by Rack, Kathrin, Huck, Volker, Hoore, Masoud, Fedosov, Dmitry A., Schneider, Stefan W., Gompper, Gerhard

“…The protein von Willebrand factor (VWF) is essential in primary hemostasis, as it mediates platelet adhesion to vessel walls. VWF retains its compact…”
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Static and dynamic light scattering by red blood cells: A numerical study by Mauer, Johannes, Peltomäki, Matti, Poblete, Simón, Gompper, Gerhard, Fedosov, Dmitry A

“…Light scattering is a well-established experimental technique, which gains more and more popularity in the biological field because it offers the means for…”
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Steady shear rheometry of dissipative particle dynamics models of polymer fluids in reverse Poiseuille flow by Fedosov, Dmitry A, Karniadakis, George Em, Caswell, Bruce

“…Polymer fluids are modeled with dissipative particle dynamics (DPD) as undiluted bead-spring chains and their solutions. The models are assessed by…”
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Multiscale modeling of red blood cell mechanics and blood flow in malaria by Fedosov, Dmitry A, Lei, Huan, Caswell, Bruce, Suresh, Subra, Karniadakis, George E

“…Red blood cells (RBCs) infected by a Plasmodium parasite in malaria may lose their membrane deformability with a relative membrane stiffening more than…”
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Effect of malaria parasite shape on its alignment at erythrocyte membrane by Dasanna, Anil K, Hillringhaus, Sebastian, Gompper, Gerhard, Fedosov, Dmitry A

“…During the blood stage of malaria pathogenesis, parasites invade healthy red blood cells (RBC) to multiply inside the host and evade the immune response. When…”
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Stochastic bond dynamics facilitates alignment of malaria parasite at erythrocyte membrane upon invasion by Hillringhaus, Sebastian, Dasanna, Anil K, Gompper, Gerhard, Fedosov, Dmitry A

“…Malaria parasites invade healthy red blood cells (RBCs) during the blood stage of the disease. Even though parasites initially adhere to RBCs with a random…”
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The Erythrocyte Sedimentation Rate and Its Relation to Cell Shape and Rigidity of Red Blood Cells from Chorea-Acanthocytosis Patients in an Off-Label Treatment with Dasatinib by Rabe, Antonia, Kihm, Alexander, Darras, Alexis, Peikert, Kevin, Simionato, Greta, Dasanna, Anil Kumar, Glaß, Hannes, Geisel, Jürgen, Quint, Stephan, Danek, Adrian, Wagner, Christian, Fedosov, Dmitry A., Hermann, Andreas, Kaestner, Lars

“…Background: Chorea-acanthocytosis (ChAc) is a rare hereditary neurodegenerative disease with deformed red blood cells (RBCs), so-called acanthocytes, as a…”
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