Search Results - "Fedorova, Tatiana N."

Evaluation of Ouabain's Tissue Distribution in C57/Black Mice Following Intraperitoneal Injection, Using Chromatography and Mass Spectrometry by Abaimov, Denis A, Kazanskaya, Rogneda B, Ageldinov, Ruslan A, Nesterov, Maxim S, Timoshina, Yulia A, Platova, Angelina I, Aristova, Irina J, Vinogradskaia, Irina S, Fedorova, Tatiana N, Volnova, Anna B, Gainetdinov, Raul R, Lopachev, Alexander V

“…Cardiotonic steroids (CTSs), such as digoxin, are used for heart failure treatment. However, digoxin permeates the brain-blood barrier (BBB), affecting central…”
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Transcriptomic changes triggered by ouabain in rat cerebellum granule cells: Role of α3- and α1-Na+,K+-ATPase-mediated signaling by Smolyaninova, Larisa V, Shiyan, Alexandra A, Kapilevich, Leonid V, Lopachev, Alexander V, Fedorova, Tatiana N, Klementieva, Tatiana S, Moskovtsev, Aleksey A, Kubatiev, Aslan A, Orlov, Sergei N

“…It was shown previously that inhibition of the ubiquitous α1 isoform of Na+,K+-ATPase by ouabain sharply affects gene expression profile via elevation of…”
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Na + ,K + -ATPase and Cardiotonic Steroids in Models of Dopaminergic System Pathologies by Markina, Alisa A, Kazanskaya, Rogneda B, Timoshina, Julia A, Zavialov, Vladislav A, Abaimov, Denis A, Volnova, Anna B, Fedorova, Tatiana N, Gainetdinov, Raul R, Lopachev, Alexander V

“…In recent years, enough evidence has accumulated to assert that cardiotonic steroids, Na ,K -ATPase ligands, play an integral role in the physiological and…”
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Modulation of the Primary Astrocyte-Enriched Cultures’ Oxylipin Profiles Reduces Neurotoxicity by Guryleva, Mariia V., Chistyakov, Dmitry V., Lopachev, Alexander V., Goriainov, Sergei V., Astakhova, Alina A., Timoshina, Yulia A., Khutorova, Anastasiya V., Fedorova, Tatiana N., Sergeeva, Marina G.

“…Recently, manipulations with reactive astrocytes have been viewed as a new therapeutic approach that will enable the development of treatments for acute brain…”
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Oxylipin Profiles in Plasma of Patients with Wilson’s Disease by Azbukina, Nadezhda V., Lopachev, Alexander V., Chistyakov, Dmitry V., Goriainov, Sergei V., Astakhova, Alina A., Poleshuk, Vsevolod V., Kazanskaya, Rogneda B., Fedorova, Tatiana N., Sergeeva, Marina G.

“…Wilson’s disease (WD) is a rare autosomal recessive metabolic disorder resulting from mutations in the copper-transporting, P-type ATPase gene ATP7B gene, but…”
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A low-cost and customizable alternative for commercial implantable cannula for intracerebral administration in mice by Kazanskaya, Rogneda B., Lopachev, Alexander V., Fedorova, Tatiana N., Gainetdinov, Raul R., Volnova, Anna B.

“…[Display omitted] Stereotaxic intracerebral cannula implantation for neuroactive agent administration is a wide-spread method for chronic experiments requiring…”
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Ouabain-Induced Gene Expression Changes in Human iPSC-Derived Neuron Culture Expressing Dopamine and cAMP-Regulated Phosphoprotein 32 and GABA Receptors by Lopachev, Alexander V, Lagarkova, Maria A, Lebedeva, Olga S, Ezhova, Margarita A, Kazanskaya, Rogneda B, Timoshina, Yulia A, Khutorova, Anastasiya V, Akkuratov, Evgeny E, Fedorova, Tatiana N, Gainetdinov, Raul R

“…Cardiotonic steroids (CTS) are specific inhibitors and endogenous ligands of a key enzyme in the CNS-the Na , K -ATPase, which maintains and creates an ion…”
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An overview of the pathogenic mechanisms involved in severe cases of COVID-19 infection, and the proposal of salicyl-carnosine as a potential drug for its treatment by Lopachev, Alexander V., Kazanskaya, Rogneda B., Khutorova, Anastasiya V., Fedorova, Tatiana N.

“…Multiple organ failure in COVID-19 patients is a serious problem which can result in a fatal outcome. Damage to organs and tissues, including general lung…”
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An assessment of the transport mechanism and intraneuronal stability of l-carnosine by Lopachev, Alexander V., Abaimov, Denis A., Filimonov, Ivan S., Kulichenkova, Kseniya N., Fedorova, Tatiana N.

“…l -Carnosine (β-alanyl- l -histidine) is a well-known antioxidant and neuroprotector in various models on animals and cell cultures. However, while there is a…”
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Impact of manganese accumulation on Na,K-ATPase expression and function in the cerebellum and striatum of C57Bl/6 mice by Smolyaninova, Larisa V., Timoshina, Yulia A., Berezhnoy, Daniil S., Fedorova, Tatiana N., Mikheev, Ivan V., Seregina, Irina F., Loginova, Nadezhda A., Dobretsov, Maxim G.

“…Overexposure to Mn causes a neurological disorder—manganism—with motor symptoms that overlap closely with disorders associated with haploinsufficiency in the…”
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Changes in COX histochemistry in the brain of mice and rats exposed to chronic subcutaneous rotenone by Berezhnoy, Daniil S., Troshev, Dmitry V., Nalobin, Denis S., Fedorova, Tatiana N.

“…•Mice and rats were chronically injected with rotenone for 1,3 and 7 days.•Time course of cell death and Cytochrome C oxidase activity in the brain was…”
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Plasma oxylipin profiles reflect Parkinson's disease stage by Chistyakov, Dmitry V., Azbukina, Nadezhda V., Lopachev, Alexander V., Goriainov, Sergei V., Astakhova, Alina A., Ptitsyna, Elena V., Klimenko, Anna S., Poleshuk, Vsevolod V., Kazanskaya, Rogneda B., Fedorova, Tatiana N., Sergeeva, Marina G.

“…Derivatives of polyunsaturated fatty acids (PUFAs), also known as oxylipins, are key participants in regulating inflammation. Neuroinflammation is involved in…”
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Neuroprotective effect of the carnosine – α-lipoic acid nanomicellar complex in a model of early-stage Parkinson's disease by Kulikova, Olga I., Berezhnoy, Daniil S., Stvolinsky, Sergey L., Lopachev, Alexander V., Orlova, Valentina S., Fedorova, Tatiana N.

“…In a model of early-stage Parkinson's disease induced by a single intranasal administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) to Wistar…”
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A new derivative of acetylsalicylic acid and carnosine: synthesis, physical and chemical properties, biological activity by Kulikova, Olga I., Stvolinsky, Sergey L., Migulin, Vasily A., Andreeva, Ludmila A., Nagaev, Igor Yu, Lopacheva, Olga M., Kulichenkova, Ksenia N., Lopachev, Alexander V., Trubitsina, Irina E., Fedorova, Tatiana N.

“…Purpose The aim of this study was to create and assess biological activity of a new compound based on carnosine and acetylsalicylic acid (ASA) that will…”
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Long-term Intracerebroventricular Administration of Ouabain Causes Motor Impairments in C57Bl/6 Mice by Timoshina, Yulia A., Kazanskaya, Rogneda B., Zavialov, Vladislav A., Volnova, Anna B., Latanov, Alexander V., Fedorova, Tatiana N., Gainetdinov, Raul R., Lopachev, Alexander V.

“…Introduction. Cardiac glycosides are natural ligands of Na+/K+-ATPase, which regulate its activity and signaling. Intracerebroventricular administration of…”
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Ouabain-induced changes in MAP kinase phosphorylation in primary culture of rat cerebellar cells by Lopachev, Alexander V., Lopacheva, Olga M., Osipova, Ekaterina A., Vladychenskaya, Elizaveta A., Smolyaninova, Larisa V., Fedorova, Tatiana N., Koroleva, Olga V., Akkuratov, Evgeny E.

“…Cardiotonic steroid (CTS) ouabain is a well‐established inhibitor of Na,K‐ATPase capable of inducing signalling processes including changes in the activity of…”
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Oxidative stress induced in rat brain by a combination of 3-nitropropionic acid and global ischemia by Dobrota, Dusan, Fedorova, Tatiana N, Stepanova, Maria S, Babusikova, Eva, Statelova, Dagmar, Tatarkova, Zuzana, Stvolinsky, Sergey S, Boldyrev, Alexander A

“…In our investigation, we describe the complex model of brain oxidative stress consisted of combination of experimental brain ischemia and energy metabolism…”
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Carnosine restores the activation of signaling cascades and the ratio of apoptosis-regulating proteins in the penumbra zone after a permanent focal cerebral ischemia in rats by Olga M. Lopacheva, Alexander V. Lopachev, Kseniya N. Kulichenkova, Alexander A. Devyatov, Daniil S. Berezhnoy, Sergey L. Stvolinsky, Olga I. Kulikova, Svetlana A. Gavrilova, Mariya P. Morozova, Tatiana N. Fedorova

“…Abstract Introduction. Ischemic stroke is one of the most common and socially significant diseases, and its pathogenesis is associated with oxidative stress…”
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