Search Results - "Fedorov, Oleg Y."
-
1
Chemical Screening Methods to Identify Ligands That Promote Protein Stability, Protein Crystallization, and Structure Determination
Published in Proceedings of the National Academy of Sciences - PNAS (24-10-2006)“…The 3D structures of human therapeutic targets are enabling for drug discovery. However, their purification and crystallization remain rate determining. In…”
Get full text
Journal Article -
2
Structural Diversity in the RGS Domain and Its Interaction with Heterotrimeric G Protein α-Subunits
Published in Proceedings of the National Academy of Sciences - PNAS (29-04-2008)“…Regulator of G protein signaling (RGS) proteins accelerate GTP hydrolysis by Gα subunits and thus facilitate termination of signaling initiated by G…”
Get full text
Journal Article -
3
Structural Basis of Inhibitor Specificity of the Human Protooncogene Proviral Insertion Site in Moloney Murine Leukemia Virus (PIM-1) Kinase
Published in Journal of medicinal chemistry (01-12-2005)“…The kinase PIM-1 plays a pivotal role in cytokine signaling and is implicated in the development of a number of tumors. The three-dimensional structure of…”
Get full text
Journal Article -
4
Resonance assignment of the RGS domain of human RGS10
Published in Journal of biomolecular NMR (01-06-2007)Get full text
Journal Article -
5
Structural diversity in the RGS domain and its interaction with heterotrimeric G protein [alpha]-subunits
Published in Proceedings of the National Academy of Sciences - PNAS (29-04-2008)“…Regulator of G protein signaling (RGS) proteins accelerate GTP hydrolysis by Gα subunits and thus facilitate termination of signaling initiated by G…”
Get full text
Journal Article