Search Results - "Fedoros, E. I."

Antigenotoxic Activity of Polyphenolic Composition BP-C2 in Mouse Germ Cells In Vivo by Zhanataev, A. K., Anisina, E. A., Malikova, A. D., Pligina, K. L., Pigarev, S. E., Fedoros, E. I., Durnev, A. D., Anisimov, V. N.

“…In vivo antigenotoxic activity of BP-C2 composition (at doses of 60, 80, and 120 mg/kg) based on polyphenolic compounds derived from hydrolyzed lignin was…”
Get full text

Development of a Protocol for Obtaining a Homologous Cell Product of Animal Origin Intended for Preclinical Studies of Antitumor Vaccine CaTeVac by Nekhaeva, T. L., Laskov, I. D., Fedoros, E. I., Danilova, A. B., Efremova, N. A., Emelyanova, N. V., Blokhina, M. L., Grigoryevskaya, A. V., Baldueva, I. A.

“…When developing a program of preclinical studies of human cell-based drugs intended for adoptive immunotherapy of cancer patients, the biological effect should…”
Get full text

Approbation of a Homologous Model of the Antitumor Vaccine Based on Mature Mouse Dendritic Cells to Study the Biodistribution of the Cell Product by Nekhaeva, T. L., Laskov, I. D., Fedoros, E. I., Danilova, A. B., Yurova, M. N., Tyndyk, M. L., Ermakova, E. D., Emelyanova, N. V., Efremova, N. A., Grigorevskaya, A. V., Nekrasova, M. A., Baldueva, I. A.

“…Homologous animal cell product was obtained in protocol developed for female BALB/c mice. Dendritic cell (DC) migration from the injection site into the…”
Get full text

Model of Accelerated Aging in CB6F2 Mice Induced by Ionizing Radiation by Yakunchikova, E. A., Yurova, M. N., Drachyov, I. S., Radetskaya, E. A., Altukhov, K. V., Semenov, A. L., Panchenko, A. V., Tyndyk, M. L., Bykov, V. N., Fedoros, E. I.

“…A model for accelerated aging in mice was developed: CB6F2 mice aged 39-45 days were exposed to fractionated 4-fold relatively uniform γ-radiation ( 137 Cs,…”
Get full text

Effect of Polyphenolic Composition BP-C2 on Lung Carcinogenesis Induced by Urethane in Progeny of Irradiated Male BALB/c Mice by Pigarev, S. E., Panchenko, A. V., Fedoros, E. I., Drachev, I. S., Kraev, S. Yu, Yakunchikova, E. A., Yurova, M. N., Semenov, A. L., Maidin, M. A., Zhanataev, A. K., Durnev, A. D., Anisimov, V. N.

“…We studied the effects of polyphenolic composition BP-C2, comprising molybdenum with lignin derivatives, on lung carcinogenesis induced by urethane in the…”
Get full text

The Effect of Inactivating Heterozygous Mutation in NBS1 Gene on DNA Damage and Repair Markers and Apoptosis Markers in Mice by Yurova, M. N., Golubev, A. G., Aleksakhina, S. N., Fedoros, E. I., Tumanyan, I. A., Otradnova, E. A., Soloviev, I. V., Sergiev, P. V., Imyanitov, E. N.

“…We studied the state of the DNA repair system and apoptosis in young mice carrying heterozygous inactivating mutation in the NBS1 gene ( c.1971insT ,…”
Get full text

Synthesis and Radio-Oncological Efficiency of Gold Glyco-Nanoparticles Based on the Aldose Condensation Products with Lipoic (Thioctic) Hydrazide by Ershov, A. Yu, Martynenkov, A. A., Lagoda, I. V., Batyrenko, A. A., Drachev, I. S., Yakunchikova, E. A., Fedoros, E. I., Kruglov, S. S., Kopanitsa, M. A., Yakimansky, A. V.

“…Structure of previously unknown aldose 1,2-dithiolan-3-pentanoyl hydrazones—condensation products of a series of monosaccharides (L-fucose, L-rhamnose,…”
Get full text

Evaluation of the genotoxic and antigenotoxic potential of lignin-derivative BP-C2 in the comet assay in vivo by Pigarev, S.E., Trashkov, A.P., Panchenko, A.V., Yurova, M.N., Bykov, V.N., Fedoros, E.I., Anisimov, V.N.

“…The genotoxic and antigenotoxic potential of BP-C2, a novel lignin-derived polyphenolic composition with ammonium molybdate, was investigated as a…”
Get full text

Exploring bioactivity potential of polyphenolic water-soluble lignin derivative by Fedoros, E.I., Baldueva, I.A., Perminova, I.V., Badun, G.A., Chernysheva, M.G., Grozdova, I.D., Melik-Nubarov, N.S., Danilova, A.B., Nekhaeva, T.L., Kuznetsova, A.I., Emelyanova, N.V., Ryakhovskiy, A.A., Pigarev, S.E., Semenov, A.L., Tyndyk, M.L., Gubareva, E.A., Panchenko, A.V., Bykov, V.N., Anisimov, V.N.

“…Many natural substances exhibit anti-inflammatory activity and considerable potential in prophylaxis and treatment of allergies. Knowing exact molecular…”
Get full text

Development of in vitro laboratory models of the tumor immune microenvironment to evaluate quality parameters and specific efficacy of the dendritic cell vaccine by Nekhaeva, T. L., Danilova, A. B., Fedoros, E. I., Efremova, N. A., Emelyanova, N. V., Blokhina, M. L., Yurova, M. N., Tyndyk, M. L., Baldueva, I. A.

“…Purpose of the study: development of in vitro laboratory models to evaluate quality parameters and specific efficacy of dendritic cell vaccine (DCV). Material…”
Get full text

DEVELOPMENT AND CHARACTERISATION OF 3D SOLID TUMOUR CELL MODELS FOR INDIVIDUALIZED CANCER TREATMENT by Danilova, A. B., Nekhaeva, T. L., Efremova, N. A., Maydin, M. A., Fedoros, E. I., Baldueva, I. A.

“…Background . To solve the problems of personalized medicine in oncology, preclinical studies based on the use of three-dimensional cellular models of tumors in…”
Get full text

REVIEW OF RESEARCH ON THE RELATIONSHIP BETWEEN CIRCADIAN RHYTHMS AND CARCINOGENESIS USING ANIMAL MODELS by Kireeva, G. S., Gubareva, E. A., Maydin, M. A., Panchenko, A. V., Tyndyk, M. L., Fedoros, E. I., Kruglov, S. S., Osetnik, V. K., Anisimov, V. N.

“…Purpose of the study: to review in vivo studies on the relationship and role of various molecular genetic components of the circadian rhythm system in the…”
Get full text

Comparative Analysis of Experimental Data on the Effects of Different Polyphenols on Lifespan and Aging by Panchenko, A. V., Tyndyk, M. L., Fedoros, E. I., Maydin, M. A., Semenov, A. L., Gubareva, E. A., Golubev, A. G., Anisimov, V. N.

“…Survival curves were approximated and analyzed based on experimental data on the effect of different polyphenolic compounds on mouse lifespan with the Gompertz…”
Get full text