Search Results - "Fedorenko, Olena A"

Changes in Ion Selectivity Following the Asymmetrical Addition of Charge to the Selectivity Filter of Bacterial Sodium Channels by Fedorenko, Olena A, Khovanov, Igor A, Roberts, Stephen K, Guardiani, Carlo

“…Voltage-gated sodium channels (NaVs) play fundamental roles in eukaryotes, but their exceptional size hinders their structural resolution. Bacterial NaVs are…”
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Application of a Statistical and Linear Response Theory to Multi-Ion Na + Conduction in NaChBac by Gibby, William A T, Fedorenko, Olena A, Guardiani, Carlo, Barabash, Miraslau L, Mumby, Thomas, Roberts, Stephen K, Luchinsky, Dmitry G, McClintock, Peter V E

“…Biological ion channels are fundamental to maintaining life. In this manuscript we apply our recently developed statistical and linear response theory to…”
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Intracellular calcium channels: Inositol-1,4,5-trisphosphate receptors by Fedorenko, Olena A., Popugaeva, Elena, Enomoto, Masahiro, Stathopulos, Peter B., Ikura, Mitsuhiko, Bezprozvanny, Ilya

“…The inositol-1,4,5-trisphosphate receptors (InsP3Rs) are the major intracellular Ca2+-release channels in cells. Activity of InsP3Rs is essential for…”
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Different roles for aspartates and glutamates for cation permeation in bacterial sodium channels by Guardiani, Carlo, Fedorenko, Olena A., Khovanov, Igor A., Roberts, Stephen K.

“…A key driving force for ion channel selectivity is represented by the negative charge of the Selectivity Filter carried by aspartate (D) and glutamate (E)…”
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Sodium Binding Sites and Permeation Mechanism in the NaChBac Channel: A Molecular Dynamics Study by Guardiani, Carlo, Rodger, P. Mark, Fedorenko, Olena A, Roberts, Stephen K, Khovanov, Igor A

“…NaChBac was the first discovered bacterial sodium voltage-dependent channel, yet computational studies are still limited due to the lack of a crystal…”
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CaV1.2 and CaV1.3 voltage-gated L-type Ca2+ channels in rat white fat adipocytes by Fedorenko, Olena A, Pulbutr, Pawitra, Banke, Elin, Akaniro-Ejim, Nneoma E, Bentley, Donna C, Olofsson, Charlotta S, Chan, Sue, Smith, Paul A

“…L-type channel antagonists are of therapeutic benefit in the treatment of hyperlipidaemia and insulin resistance. Our aim was to identify L-type voltage-gated…”
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Ion channels of the nuclear membrane of hippocampal neurons by Fedorenko, Olena A., Marchenko, Sergey M.

“…ABSTRACT Rise in Ca2+ concentration in the nucleus affects gene transcription and has been implicated in neuroprotection, transcription‐dependent neuronal…”
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Covalent linkage of bacterial voltage-gated sodium channels by Sun, Huaping, Zheng, Zeyu, Fedorenko, Olena A, Roberts, Stephen K

“…Bacterial sodium channels are important models for understanding ion permeation and selectivity. However, their homotetrameric structure limits their use as…”
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