Search Results - "Fedick, Patrick"

Forensic Sampling and Analysis from a Single Substrate: Surface-Enhanced Raman Spectroscopy Followed by Paper Spray Mass Spectrometry by Fedick, Patrick W, Bills, Brandon J, Manicke, Nicholas E, Cooks, R. Graham

“…Sample preparation is the most common bottleneck in the analysis and processing of forensic evidence. Time-consuming steps in many forensic tests involve…”
Get full text

Identification and Confirmation of Fentanyls on Paper using Portable Surface Enhanced Raman Spectroscopy and Paper Spray Ionization Mass Spectrometry by Fedick, Patrick W, Pu, Fan, Morato, Nicolás M, Cooks, R. Graham

“…Fentanyl and its analogues play a major role in the current opioid epidemic. In particular, these highly potent opioids have become a health hazard due to…”
Get full text

Rapid, low-cost, and in-situ analysis of per- and polyfluoroalkyl substances in soils and sediments by ambient 3D-printed cone spray ionization mass spectrometry by Brown, Hilary M., Fedick, Patrick W.

“…A rapid method to empirically determine the presence of trace per- and polyfluoroalkyl substances (PFAS) in solid media, such as soils, sands, and sediments,…”
Get full text

Ion Mobility–Mass Spectrometry Using a Dual-Gated 3D Printed Ion Mobility Spectrometer by Hollerbach, Adam, Fedick, Patrick W, Cooks, R. Graham

“…Described herein is the development of a 3D-printed drift-tube ion mobility spectrometer (IMS) which operates in the open air and is capable of being coupled…”
Get full text

Accelerated synthesis of energetic precursor cage compounds using confined volume systems by Brown, Hilary M., Doppalapudi, Karan R., Fedick, Patrick W.

“…Confined volume systems, such as microdroplets, Leidenfrost droplets, or thin films, can accelerate chemical reactions. Acceleration occurs due to the…”
Get full text

Quantitative Swab Touch Spray Mass Spectrometry for Oral Fluid Drug Testing by Morato, Nicolás M, Pirro, Valentina, Fedick, Patrick W, Cooks, R. Graham

“…Simultaneous determination of 30 common drugs of abuse, including opioids, benzodiazepines, fentanyl derivatives, methamphetamines, cocaine, substituted…”
Get full text

Application of a Modified 3D-PCSI-MS Ion Source to On-Site, Trace Evidence Processing via Integrated Vacuum Collection by Bondzie, Ebenezer H., Adehinmoye, Adewale, Molnar, Brian T., Fedick, Patrick W., Mulligan, Christopher C.

“…Trace evidence, including hair, fibers, soil/dust, and gunshot residue (GSR), can be recovered from a crime scene to help identify or associate a suspect with…”
Get full text

From the laboratory to the field: Chemical analysis of colored smoke pyrotechnic formulations via mass spectrometry techniques by Fedick, Patrick W., Thoreson, Kelly M., Wilkins, Benjamin P., Papenmeier, Douglas M., Bohrer, Brian C., Dilger, Jonathan M.

“…Smoke dyes are complex molecular systems that have the potential to form many molecular derivatives and fragments when deployed. The chemical analysis of smoke…”
Get full text

Detection and toxicity modeling of anthraquinone dyes and chlorinated side products from a colored smoke pyrotechnic reaction by Dilger, Jonathan M., Martin, Todd M., Wilkins, Benjamin P., Bohrer, Brian C., Thoreson, Kelly M., Fedick, Patrick W.

“…“Green” pyrotechnics seek to remove known environmental pollutants and health hazards from their formulations. This chemical engineering approach often focuses…”
Get full text

Rapid screening of high-priority N-nitrosamines in pharmaceutical, forensic, and environmental samples with paper spray ionization and filter cone spray ionization-mass spectrometry by McDaniel, Trevor J, Holtz, Jessica M, Bondzie, Ebenezer H, Overfelt, Makoy, Fedick, Patrick W, Mulligan, Christopher C

“…The burgeoning concern of N-nitrosamine (NAM) contamination found in various pharmaceutical compositions has increased the demand for rapid and reliable…”
Get full text

Multigenerational Collision-Induced Dissociation for Characterization of Organic Compounds by Snyder, Dalton T., Fedick, Patrick W., Cooks, R. Graham

“…There are many cases in which limited information is obtained from a single stage of tandem mass spectrometry (MS2 or MS/MS). For example, isomeric cathinones…”
Get full text

Screening of the Suzuki Cross-Coupling Reaction Using Desorption Electrospray Ionization in High-Throughput and in Leidenfrost Droplet Experiments by Fedick, Patrick W., Iyer, Kiran, Wei, Zhenwei, Avramova, Larisa, Capek, Grace O., Cooks, R. Graham

“…Suzuki cross-coupling is a widely performed reaction, typically using metal catalysts under heated conditions. Acceleration of the Suzuki cross-coupling…”
Get full text

Novel Selectivity-Based Forensic Toxicological Validation of a Paper Spray Mass Spectrometry Method for the Quantitative Determination of Eight Amphetamines in Whole Blood by Teunissen, Sebastiaan F., Fedick, Patrick W., Berendsen, Bjorn J. A., Nielen, Michel W. F., Eberlin, Marcos N., Graham Cooks, R., van Asten, Arian C.

“…Paper spray tandem mass spectrometry is used to identify and quantify eight individual amphetamines in whole blood in 1.3 min. The method has been optimized…”
Get full text

Inspiring Future Rocket Chemists: A Hands-On Instructional Event Highlighting the Role Chemistry plays in the Fundamentals of Rocketry by Fedick, Patrick W., Bryan, Aimee M., Smith, Robert D., Austin, Jessica S., DeKorver, Brittland K.

“…Motivational hands-on workshops for grade-school level future scientists are needed to inspire young and receptive minds. Described here is an educational…”
Get full text

Accelerated Chemical Synthesis: Three Ways of Performing the Katritzky Transamination Reaction by Schrader, Robert L, Fedick, Patrick W, Mehari, Tsdale F, Cooks, R. Graham

“…Typical laboratory exercises for undergraduate organic chemistry students involve bulk phase reactions with work up of product. In this study, students…”
Get full text

Analysis of Residual Explosives by Swab Touch Spray Ionization Mass Spectrometry by Bain, Ryan M., Fedick, Patrick W., Dilger, Jonathan M., Cooks, R. Graham

“…Swab touch spray ionization mass spectrometry, an ambient ionization technique, has been applied to the analysis of six explosives from various surfaces…”
Get full text

Process Analytical Technology for Online Monitoring of Organic Reactions by Mass Spectrometry and UV–Vis Spectroscopy by Fedick, Patrick W, Schrader, Robert L, Ayrton, Stephen T, Pulliam, Christopher J, Cooks, R. Graham

“…Process analytical technologies (PATs) are used in the pharmaceutical and other industries to monitor chemical processes in real-time with analytical…”
Get full text

Simultaneous Online Monitoring of Multiple Reactions Using a Miniature Mass Spectrometer by Pulliam, Christopher J, Bain, Ryan M, Osswald, Heather L, Snyder, Dalton T, Fedick, Patrick W, Ayrton, Stephen T, Flick, Tawnya G, Cooks, R. Graham

“…Advances in chemical sampling using miniature mass spectrometer technology are used to monitor slow reactions at a frequency of ca. 180 h–1 (on the Mini 12)…”
Get full text

Solubility of hydrocarbon oils in alcohols (≤C) and synthesis of difusel carbonate for degreasing by Davis, Matthew C, Fedick, Patrick W, Lupton, David V, Ostrom, Gregory S, Quintana, Roxanne, Woodroffe, Josanne-Dee

“…The empirical solubility of hydrocarbon fluids, polyalphaolefin (PAO) and mineral oil, in thirteen small molecular weight alcohols (C 1 -C 6 ) was determined…”
Get full text

A Low-Cost, Simplified Platform of Interchangeable, Ambient Ionization Sources for Rapid, Forensic Evidence Screening on Portable Mass Spectrometric Instrumentation by Fedick, Patrick, Fatigante, William, Lawton, Zachary, O’Leary, Adam, Hall, Seth, Bain, Ryan, Ayrton, Stephen, Ludwig, Joseph, Mulligan, Christopher

“…Portable mass spectrometers (MS) are becoming more prevalent due to improved instrumentation, commercialization, and the robustness of new ionization…”
Get full text