Search Results - "Fedetz, Maria"
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Associative Conditioning Is a Robust Systemic Behavior in Unicellular Organisms: An Interspecies Comparison
Published in Frontiers in microbiology (19-07-2021)“…The capacity to learn new efficient systemic behavior is a fundamental issue of contemporary biology. We have recently observed, in a preliminary analysis, the…”
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Self-Organization and Information Processing: From Basic Enzymatic Activities to Complex Adaptive Cellular Behavior
Published in Frontiers in genetics (21-05-2021)“…One of the main aims of current biology is to understand the origin of the molecular organization that underlies the complex dynamic architecture of cellular…”
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Polymorphisms in ARNTL/BMAL1 and CLOCK Are Not Associated with Multiple Sclerosis in Spanish Population
Published in Biology (Basel, Switzerland) (28-09-2022)“…Disrupted circadian cycle has been reported in multiple sclerosis (MS). Previous genome-wide association studies (GWAS) singled out over 230 variants…”
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Genome-wide association study of multiple sclerosis confirms a novel locus at 5p13.1
Published in PloS one (03-05-2012)“…Multiple Sclerosis (MS) is the most common progressive and disabling neurological condition affecting young adults in the world today. From a genetic point of…”
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High ACSL5 transcript levels associate with systemic lupus erythematosus and apoptosis in Jurkat T lymphocytes and peripheral blood cells
Published in PloS one (06-12-2011)“…Systemic lupus erythematosus (SLE) is a prototypical autoimmune disease in which increased apoptosis and decreased apoptotic cells removal has been described…”
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Fine mapping and functional analysis of the multiple sclerosis risk gene CD6
Published in PloS one (24-04-2013)“…CD6 has recently been identified and validated as risk gene for multiple sclerosis (MS), based on the association of a single nucleotide polymorphism (SNP),…”
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Effects of the multiple sclerosis associated −330 promoter polymorphism in IL2 allelic expression
Published in Journal of neuroimmunology (01-03-2004)“…The −330 IL2 gene promoter polymorphism has been associated with multiple sclerosis (MS) [J. Neuroimmunol. 119 (2001) 101], but the basis underlying this…”
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The high producer variant of the Fc-receptor like-3 ( FCRL3 ) gene is involved in protection against multiple sclerosis
Published in Journal of neuroimmunology (01-03-2008)“…Abstract Some polymorphisms in the FCRL3 gene, a member of the Fc-receptor like family, have been associated with several autoimmune diseases and recently with…”
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Evidence of conditioned behavior in amoebae
Published in Nature communications (15-08-2019)“…Associative memory is the main type of learning by which complex organisms endowed with evolved nervous systems respond efficiently to certain environmental…”
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Splice-site variant in ACSL5: a marker promoting opposing effect on cell viability and protein expression
Published in European journal of human genetics : EJHG (01-12-2019)“…Long-chain Acyl-CoA synthetases (ACSLs) activate fatty acids (FAs) by thioesterification with Coenzyme A (CoA), generating FA-CoAs. These products are…”
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SP140 regulates the expression of immune-related genes associated with multiple sclerosis and other autoimmune diseases by NF-κB inhibition
Published in Human molecular genetics (01-12-2018)“…Abstract SP140 locus has been associated with multiple sclerosis (MS) as well as other autoimmune diseases by genome-wide association studies (GWAS). The…”
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High susceptibility of a human oligodendroglial cell line to herpes simplex type 1 infection
Published in Journal of neurovirology (01-04-2005)“…More than 20 infectious agents, ranging from retroviruses to mycobacteria, have been associated with multiple sclerosis onset or relapses in which…”
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Multiple sclerosis risk variant HLA-DRB11501 associates with high expression of DRB1 gene in different human populations
Published in PloS one (13-01-2012)“…The human leukocyte antigen (HLA) DRB1*1501 has been consistently associated with multiple sclerosis (MS) in nearly all populations tested. This points to a…”
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The multiple sclerosis-associated regulatory variant rs10877013 affects expression of CYP27B1 and VDR under inflammatory or vitamin D stimuli
Published in Multiple sclerosis (01-07-2016)“…Background: Vitamin D deficit is considered an important risk factor for many inflammatory and autoimmune diseases. Objective: To investigate the influence of…”
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Human endogenous retrovirus HERV-Fc1 association with multiple sclerosis susceptibility: a meta-analysis
Published in PloS one (03-03-2014)“…Human endogenous retroviruses (HERVs) are repetitive sequences derived from ancestral germ-line infections by exogenous retroviruses and different HERV…”
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The nucleus does not significantly affect the migratory trajectories of amoeba in two-dimensional environments
Published in Scientific reports (08-11-2019)“…For a wide range of cells, from bacteria to mammals, locomotion movements are a crucial systemic behavior for cellular life. Despite its importance in a…”
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IL2RA/CD25 gene polymorphisms: uneven association with multiple sclerosis (MS) and type 1 diabetes (T1D)
Published in PloS one (2009)“…IL-2 receptor (IL2R) alpha is the specific component of the high affinity IL2R system involved in the immune response and in the control of autoimmunity. Here…”
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A splice variant in the ACSL5 gene relates migraine with fatty acid activation in mitochondria
Published in European journal of human genetics : EJHG (01-11-2016)“…Genome-wide association studies (GWAS) in migraine are providing the molecular basis of this heterogeneous disease, but the understanding of its aetiology is…”
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Genome-wide CTCF distribution in vertebrates defines equivalent sites that aid the identification of disease-associated genes
Published in Nature structural & molecular biology (01-06-2011)“…Identifying genes associated with SNPs in non-coding regions is difficult as the SNPs are often located far from the promoters they impact. Cross-species…”
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Dynamic properties of calcium-activated chloride currents in Xenopus laevis oocytes
Published in Scientific reports (13-02-2017)“…Chloride is the most abundant permeable anion in the cell, and numerous studies in the last two decades highlight the great importance and broad physiological…”
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