Search Results - "Federlein, Anna"

Empagliflozin increases kidney weight due to increased cell size in the proximal tubule S3 segment and the collecting duct by Sinha, Frederick, Federlein, Anna, Biesold, Annika, Schwarzfischer, Magdalena, Krieger, Katharina, Schweda, Frank, Tauber, Philipp

“…The inhibition of renal SGLT2 glucose reabsorption has proven its therapeutic efficacy in chronic kidney disease. SGLT2 inhibitors (SGLTi) have been…”
Get full text

Natriuretic peptides relax human intrarenal arteries through natriuretic peptide receptor type‐A recapitulated by soluble guanylyl cyclase agonists by Frees, Andreas, Assersen, Kasper B., Jensen, Mia, Hansen, Pernille B.L., Vanhoutte, Paul M., Madsen, Kirsten, Federlein, Anna, Lund, Lars, Toft, Anja, Jensen, Boye L.

“…Aim Natriuretic peptides, BNP and ANP increase renal blood flow in experimental animals. The signalling pathway in human kidney vasculature is unknown. It was…”
Get full text

Natriuretic Peptide Receptor Guanylyl Cyclase-A in Podocytes is Renoprotective but Dispensable for Physiologic Renal Function by Staffel, Janina, Valletta, Daniela, Federlein, Anna, Ehm, Katharina, Volkmann, Regine, Füchsl, Andrea M, Witzgall, Ralph, Kuhn, Michaela, Schweda, Frank

“…The cardiac natriuretic peptides (NPs), atrial NP and B-type NP, regulate fluid homeostasis and arterial BP through renal actions involving increased GFR and…”
Get full text

Natriuretic Peptides Exert Marked Renoprotective Effects Via Activation of the Natriuretic Peptide Receptor GC‐A in Podocytes by Staffel, Janina, Valletta, Daniela, Federlein, Anna, Kuhn, Michaela, Schweda, Frank

“…Abstract only…”
Get full text

Renin cells with defective Gsα/cAMP signaling contribute to renal endothelial damage by Steglich, Anne, Kessel, Friederike, Hickmann, Linda, Gerlach, Michael, Lachmann, Peter, Gembardt, Florian, Lesche, Mathias, Dahl, Andreas, Federlein, Anna, Schweda, Frank, Hugo, Christian P. M., Todorov, Vladimir T.

“…Synthesis of renin in renal renin-producing cells (RPCs) is controlled via the intracellular messenger cAMP. Interference with cAMP-mediated signaling by…”
Get full text

Abstract B08: The role of periostin in pancreatic carcinogenesis and metastatic spread by Hausmann, Simone, Regel, Ivonne, Federlein, Anna, Mazur, Pawel K., Steiger, Katja, Michalski, Christoph W., Erkan, Mert, Kleeff, Jörg

“…Background: Excessive desmoplasia is a typical feature of pancreatic ductal adenocarcinoma (PDAC) and is highly associated with an aggressive tumor phenotype…”
Get full text

Periostin promotes pancreatic carcinogenesis and metastatic spread by Hausmann, Simone, Regel, Ivonne, Mazur, Pawel, Federlein, Anna, Wagner, Nadine, Steiger, Katja, Michalski, Christoph, Erkan, Mert, Friess, Helmut, Kleeff, Joerg

“…[...]the development of therapeutic drugs directed against periostin and its downstream targets might be a promising approach to inhibit pancreatic…”
Get full text