Search Results - "Federico Oppenheimer"
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Complement-Activating Anti-HLA Antibodies in Kidney Transplantation: Allograft Gene Expression Profiling and Response to Treatment
Published in Journal of the American Society of Nephrology (01-02-2018)“…Complement-activating anti-HLA donor-specific antibodies (DSAs) are associated with impaired kidney transplant outcome; however, whether these antibodies…”
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Application of the iBox prognostication system as a surrogate endpoint in the TRANSFORM randomised controlled trial: proof-of-concept study
Published in BMJ open (07-10-2021)“…ObjectivesDevelopment of pharmaceutical agents in transplantation is currently limited by long waits for hard endpoints. We applied a validated integrative…”
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3
Antiphospholipase A2 Receptor Antibody Levels Predict the Risk of Posttransplantation Recurrence of Membranous Nephropathy
Published in Transplantation (01-08-2015)“…Secretory phospholipase A2 receptor (PLA2R) is the target antigen of the auto-antibodies produced in most (∼ 70%) patients with primary membranous nephropathy…”
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mTOR inhibitor–associated proteinuria in kidney transplant recipients
Published in Transplantation reviews (Philadelphia, Pa.) (2012)“…Abstract The use of mammalian target of rapamycin inhibitor (mTOR-I) after kidney transplantation has been associated with a higher incidence of proteinuria…”
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Rituximab, plasma exchange and immunoglobulins: an ineffective treatment for chronic active antibody-mediated rejection
Published in BMC nephrology (11-10-2018)“…Chronic active antibody-mediated rejection (c-aABMR) is an important cause of allograft failure and graft loss in long-term kidney transplants. To determine…”
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Pharmacokinetic modeling of enterohepatic circulation of mycophenolic acid in renal transplant recipients
Published in Kidney international (01-06-2014)“…Several factors contribute to mycophenolic acid (MPA) between-patient variability. Here we characterize the metabolic pathways of MPA and quantify the effect…”
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Efficacy of Eculizumab in the Treatment of Recurrent Atypical Hemolytic-Uremic Syndrome After Renal Transplantation
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Tofacitinib halts progression of graft dysfunction in a rat model of mixed cellular and humoral rejection
Published in Transplantation (01-07-2018)“…BACKGROUNDThe progression from acute to chronic antibody-mediated rejection in kidney transplant recipients is usually not prevented by current therapeutic…”
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Psychosocial risk factors for impaired health-related quality of life in living kidney donors: results from the ELIPSY prospective study
Published in Scientific reports (07-12-2020)“…Living kidney donors’ follow-up is usually focused on the assessment of the surgical and medical outcomes. Whilst the psychosocial follow-up is advocated in…”
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Assessment of donor satisfaction as an essential part of living donor kidney transplantation: an eleven-year retrospective study
Published in Transplant international (01-12-2018)“…Living kidney donors seem highly satisfied with donation. However, previous studies measure satisfaction by a single-item or by simply questioning donors'…”
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Perioperative prophylaxis with ertapenem reduced infections caused by extended-spectrum betalactamase-producting Enterobacteriaceae after kidney transplantation
Published in BMC nephrology (22-07-2019)“…In recent years we have witnessed an increase in infections due to multidrug-resistant organisms in kidney transplant recipients (KTR). In our setting, we have…”
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Predictors of Success in Conversion from Calcineurin Inhibitor to Sirolimus in Chronic Allograft Dysfunction
Published in American journal of transplantation (01-11-2004)“…Chronic allograft dysfunction (CAD) is a major cause of graft loss in long‐term kidney transplant recipients. To identify predictors of successful conversion…”
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Antifungal prophylaxis with nebulized amphotericin-B in solid-organ transplant recipients with severe COVID-19: a retrospective observational study
Published in Frontiers in cellular and infection microbiology (27-04-2023)“…COVID-19-associated pulmonary aspergillosis (CAPA) has emerged as a frequent complication in the intensive care unit (ICU). However, little is known about this…”
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14
Impact of Mesenchymal Stromal Cells and Their Extracellular Vesicles in a Rat Model of Kidney Rejection
Published in Frontiers in cell and developmental biology (29-01-2020)“…Mesenchymal stromal cells (MSCs) from different sources possess great therapeutic potential due to their immunomodulatory properties associated with allograft…”
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The pharmacokinetics of mycophenolate mofetil in renal transplant recipients receiving standard-dose or low-dose cyclosporine, low-dose tacrolimus or low-dose sirolimus: the Symphony pharmacokinetic substudy
Published in Nephrology, dialysis, transplantation (01-07-2009)“…Background. Exposure to mycophenolic acid (MPA), the primary active metabolite of mycophenolate mofetil (MMF), is correlated with therapeutic efficacy of MMF…”
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Long-term outcome of antineutrophil cytoplasmic antibody-associated small vessel vasculitis after renal transplantation
Published in Clinical transplantation (01-05-2013)“…The survival after renal transplantation of patients with antineutrophil cytoplasmic antibody (ANCA)‐associated to systemic vasculitis is as good as in other…”
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Recommendations for the use of everolimus in de novo kidney transplantation: False beliefs, myths and realities
Published in Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia (01-05-2017)“…The immunosuppressive combination most commonly used in de novo kidney transplantation comprises a calcineurin inhibitor (CI), tacrolimus, a mycophenolic acid…”
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B Cell-Derived Extracellular Vesicles Reveal Residual B Cell Activity in Kidney Graft Recipients Undergoing Pre-Transplant Desensitization
Published in Frontiers in medicine (16-12-2021)“…Living-donor kidney transplant (LDKT) recipients undergoing desensitization for Human Leukocyte Antigen (HLA)-incompatibility have a high risk of developing…”
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Influence of Persistent Inflammation in Follow-Up Biopsies After Antibody-Mediated Rejection in Kidney Transplantation
Published in Frontiers in medicine (12-11-2021)“…Background: Despite recent advances in immunosuppression treatment, antibody-mediated rejection (ABMR) remains the leading cause of kidney graft loss…”
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An mTOR-inhibitor-based protocol and calcineurin inhibitor (CNI)-free treatment in kidney transplant recipients from donors after cardiac death: good renal function, but high incidence of conversion to CNI
Published in Transplant international (01-03-2016)“…Donor after cardiac death (DCD) grafts have excellent survival despite the high incidence of delayed graft function (DGF). We assessed the feasibility of a…”
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