The Enhancement of COVID-19 Severity on Coagulation Markers: a Cross-sectional Study in West Sumatra, Indonesia
Objective: This study aimed to determine the description of the coagulation marker and how it implicates COVID-19 patients based on clinical outcomes in the form of enhancement severity and death. Method: The subjects were collected from patients with positive COVID-19 RT-PCR with medical records in...
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| Published in: | Majalah kedokteran Andalas Vol. 46; no. 10; p. 1712 |
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| Main Authors: | , , , |
| Format: | Journal Article |
| Language: | English |
| Published: |
31-05-2024
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| Online Access: | Get full text |
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| Summary: | Objective: This study aimed to determine the description of the coagulation marker and how it implicates COVID-19 patients based on clinical outcomes in the form of enhancement severity and death. Method: The subjects were collected from patients with positive COVID-19 RT-PCR with medical records including demographic data, and laboratory results such as hemoglobin, hematocrit, leukocytes, platelets, coagulation markers (D-dimer, PT, and APTT), and patients outcomes post-treatment. Statistical analysis is performed by using chi-square and Mann-Whitney tests were considered statistically difference level of significant between variables. Result: The COVID-19 patients is classified into mild group with 27 subjects (44.2%) and moderate-severe group 34 subjects (55.8%). Leukocytes, D-dimer, and PT levels significantly differed between mild and moderate-severe groups. All coagulation markers had a symptomatic effect on Covid-19 patients, increased D-dimer and prolonged prothrombin time in adult COVID-19 patients tend to be followed by the enhancement of severe symptoms and death |
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| ISSN: | 0126-2092 2442-5230 |
| DOI: | 10.25077/mka.v46.i10.p1712-1723.2024 |