Search Results - "Fearing, Bailey V."
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In vitro response of macrophage polarization to a keratin biomaterial
Published in Acta biomaterialia (01-07-2014)“…Treatment of THP-1 derived macrophages with keratin results in a predominance of M2 (anti-inflammatory) macrophages. [Display omitted] Macrophage response to…”
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Journal Article -
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Mechanosensitive transcriptional coactivators MRTF‐A and YAP/TAZ regulate nucleus pulposus cell phenotype through cell shape
Published in The FASEB journal (01-12-2019)“…Cells of the adult nucleus pulposus (NP) are critically important in maintaining overall disc health and function. NP cells reside in a soft, gelatinous matrix…”
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Journal Article -
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Mechanotransduction and cell biomechanics of the intervertebral disc
Published in JOR-spine (01-09-2018)“…Mechanical loading of the intervertebral disc (IVD) initiates cell‐mediated remodeling events that contribute to disc degeneration. Cells of the IVD, nucleus…”
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Journal Article -
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Control of adhesive ligand density for modulation of nucleus pulposus cell phenotype
Published in Biomaterials (01-08-2020)“…Cells of the nucleus pulposus have been observed to undergo a shift from their notochordal-like juvenile phenotype to a more fibroblast-like state with age and…”
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Journal Article -
5
Regulation of human nucleus pulposus cells by peptide-coupled substrates
Published in Acta biomaterialia (01-06-2017)“…[Display omitted] Nucleus pulposus (NP) cells are derived from the notochord and differ from neighboring cells of the intervertebral disc in phenotypic marker…”
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Journal Article -
6
Verteporfin treatment controls morphology, phenotype, and global gene expression for cells of the human nucleus pulposus
Published in JOR-spine (01-12-2020)“…Cells of the nucleus pulposus (NP) are essential contributors to extracellular matrix synthesis and function of the intervertebral disc. With age and…”
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Journal Article -
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Aged adipose derived stem cells are more proliferative and less responsive to differentiation cues
Published in The FASEB journal (01-04-2009)“…Abstract only…”
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Journal Article -
8
A keratin biomaterial for treatment following spinal cord hemisection injury and investigation of secondary damage mechanisms
Published 2014“…Spinal cord injuries (SCI) are a severely debilitating injury that affects about 200,000 people in the United States alone. The only current treatment options…”
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Dissertation -
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The development of biomaterials from porcine skeletal muscle extracellular matrix
Published in The FASEB journal (01-04-2009)“…Abstract only…”
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Journal Article