Search Results - "Feagins, Alicia R."
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Ebola Virus VP24 Targets a Unique NLS Binding Site on Karyopherin Alpha 5 to Selectively Compete with Nuclear Import of Phosphorylated STAT1
Published in Cell host & microbe (13-08-2014)“…During antiviral defense, interferon (IFN) signaling triggers nuclear transport of tyrosine-phosphorylated STAT1 (PY-STAT1), which occurs via a subset of…”
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Rescue of a genotype 4 human hepatitis E virus from cloned cDNA and characterization of intergenotypic chimeric viruses in cultured human liver cells and in pigs
Published in Journal of general virology (01-10-2012)“…Hepatitis E virus (HEV) is an important but extremely understudied human pathogen. Genotypes 1 and 2 are restricted to humans, whereas genotypes 3 and 4 are…”
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3
Restricted Enzooticity of Hepatitis E Virus Genotypes 1 to 4 in the United States
Published in Journal of Clinical Microbiology (01-12-2011)“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Neisseria meningitidis Serogroup C Clonal Complex 10217 Outbreak in West Kpendjal Prefecture, Togo 2019
Published in Microbiology spectrum (27-04-2022)“…Togo has reported seasonal meningitis outbreaks caused by non-Neisseria meningitidis serogroup A (NmA) pathogens since the introduction of meningococcal…”
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5
Lloviu virus VP24 and VP35 proteins function as innate immune antagonists in human and bat cells
Published in Virology (New York, N.Y.) (01-11-2015)“…Abstract Lloviu virus (LLOV) is a new member of the filovirus family that also includes Ebola virus (EBOV) and Marburg virus (MARV). LLOV has not been…”
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Amino Acid Residue at Position 79 of Marburg Virus VP40 Confers Interferon Antagonism in Mouse Cells
Published in The Journal of infectious diseases (01-10-2015)“…Marburg viruses (MARVs) cause highly lethal infections in humans and nonhuman primates. Mice are not generally susceptible to MARV infection; however, if the…”
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7
Next generation rapid diagnostic tests for meningitis diagnosis
Published in The Journal of infection (01-11-2020)“…•Existing meningitis RDTs have characteristics that limit their global implementation at various levels of care.•Next generation meningitis RDTs will have…”
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The Strengthening of Laboratory Systems in the Meningitis Belt to Improve Meningitis Surveillance, 2008-2018: A Partners' Perspective
Published in The Journal of infectious diseases (31-10-2019)“…Laboratories play critical roles in bacterial meningitis disease surveillance in the African meningitis belt, where the highest global burden of meningitis…”
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The VP40 protein of Marburg virus exhibits impaired budding and increased sensitivity to human tetherin following mouse adaptation
Published in Journal of virology (01-12-2014)“…The Marburg virus VP40 protein is a viral matrix protein that spontaneously buds from cells. It also functions as an interferon (IFN) signaling antagonist by…”
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10
Implementation of Case-Based Surveillance and Real-time Polymerase Chain Reaction to Monitor Bacterial Meningitis Pathogens in Chad
Published in The Journal of infectious diseases (31-10-2019)“…Meningococcal serogroup A conjugate vaccine (MACV) was introduced in Chad during 2011-2012. Meningitis surveillance has been conducted nationwide since 2003,…”
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Senataxin suppresses the antiviral transcriptional response and controls viral biogenesis
Published in Nature immunology (01-05-2015)“…Mutations in the gene encoding the helicase senataxin have well established associations with the neurodegenerative disease ALS. Marazzi et al . show that…”
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Prior infection of pigs with a genotype 3 swine hepatitis E virus (HEV) protects against subsequent challenges with homologous and heterologous genotypes 3 and 4 human HEV
Published in Virus research (01-07-2011)“…► In this study, we determined if prior HEV infection protects against HEV challenge. ► The pigs inoculated with swine HEV developed anti-HEV antibodies prior…”
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Intergenotypic chimeric hepatitis E viruses (HEVs) with the genotype 4 human HEV capsid gene in the backbone of genotype 3 swine HEV are infectious in pigs
Published in Virus research (01-03-2011)“…Genotypes 1 and 2 hepatitis E virus (HEV) infect only humans whereas genotypes 3 and 4 HEV infect both humans and pigs. To evaluate the mechanism of…”
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Development of a fluorescent microbead-based immunoassay for the detection of hepatitis E virus IgG antibodies in pigs and comparison to an enzyme-linked immunoassay
Published in Journal of virological methods (01-11-2013)“…•Hepatitis E virus (HEV) infection in pigs is common and of zoonotic concern.•ELISA assays are currently used for detection of swine anti-HEV antibodies.•A…”
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15
The helicase senataxin suppresses the antiviral transcriptional response and controls viral biogenesis
Published in Nature immunology (30-03-2015)“…The human helicase senataxin (SETX) is implicated in the neurodegenerative diseases amyotrophic lateral sclerosis (ALS4) and ataxia with oculomotor apraxia…”
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Ebola virus VP24 targets a unique NLS-binding site on karyopherin5 to selectively compete with nuclear import of phosphorylated STAT1
Published in Cell host & microbe (13-08-2014)“…During anti-viral defense, interferon (IFN) signaling triggers nuclear transport of tyrosine phosphorylated STAT1 (PY-STAT1), which occurs via a subset of…”
Get full text
Journal Article -
17
Ebola Virus VP24 Targets a Unique NLS Binding Site on Karyopherin Alpha 5 to Selectively Compete with Nuclear Import of Phosphorylated STAT1
Published in Cell host & microbe (01-08-2014)Get full text
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