Search Results - "Fazzi, Gregorio E"

Expression of proteins associated with the Warburg‐effect and survival in colorectal cancer by Offermans, Kelly, Jenniskens, Josien CA, Simons, Colinda CJM, Samarska, Iryna, Fazzi, Gregorio E, Smits, Kim M, Schouten, Leo J, Weijenberg, Matty P, Grabsch, Heike I, Brandt, Piet A

“…Previous research has suggested that the expression of proteins related to the Warburg effect may have prognostic value in colorectal cancer (CRC), but results…”
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Association between mutational subgroups, Warburg‐subtypes, and survival in patients with colorectal cancer by Offermans, Kelly, Jenniskens, Josien C. A., Simons, Colinda C. J. M., Samarska, Iryna, Fazzi, Gregorio E., Meer, Jaleesa R. M., Smits, Kim M., Schouten, Leo J., Weijenberg, Matty P., Grabsch, Heike I., Brandt, Piet A.

“…Background Previous research suggests that Warburg‐subtypes are related to potentially important survival differences in colorectal cancer (CRC) patients. In…”
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Functional antagonism between endogenous neuropeptide Y and calcitonin gene-related peptide in mesenteric resistance arteries by De Mey, Jo G R, Megens, Remco, Fazzi, Gregorio E

“…To test the hypothesis that endogenous neuropeptide Y (NPY) counteracts the vasodilator effects of calcitonin gene-related peptide (CGRP), we used isolated…”
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Calcitonin gene-related peptide selectively relaxes contractile responses to endothelin-1 in rat mesenteric resistance arteries by Meens, Merlijn J P M T, Fazzi, Gregorio E, van Zandvoort, Marc A, De Mey, Jo G R

“…We tested the hypothesis that endothelin-1 (ET-1) modulates sensory-motor nervous arterial relaxation by prejunctional and postjunctional mechanisms. Isolated…”
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Irreversible renal damage after transient renin-angiotensin system stimulation: involvement of an AT1-receptor mediated immune response by Heijnen, Bart F J, Nelissen, Jelly, van Essen, Helma, Fazzi, Gregorio E, Cohen Tervaert, Jan W, Peutz-Kootstra, Carine J, Mullins, John J, Schalkwijk, Casper G, Janssen, Ben J A, Struijker-Boudier, Harry A J

“…Transient activation of the renin-angiotensin system (RAS) induces irreversible renal damage causing sustained elevation in blood pressure (BP) in Cyp1a1-Ren2…”
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Impaired flow-induced arterial remodeling in DOCA-salt hypertensive rats by Lemkens, Pieter, Nelissen, Jelly, Meens, Merlijn J P M T, Fazzi, Gregorio E, Janssen, Ger J M, Debets, Jacques J M, Janssen, Ben J A, Schiffers, Paul M H, De Mey, Jo G R

“…Arteries from young healthy animals respond to chronic changes in blood flow and blood pressure by structural remodeling. We tested whether the ability to…”
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Association between Long-term Energy Balance-Related Factors and Survival in Colorectal Cancer Overall and by Metabolic Warburg-Subtypes by Offermans, Kelly, Jenniskens, Josien C A, Simons, Colinda C J M, Samarska, Iryna, Fazzi, Gregorio E, Smits, Kim M, Schouten, Leo J, Weijenberg, Matty P, Grabsch, Heike I, van den Brandt, Piet A

“…Long-term energy balance-related factors (i.e., lifestyle and physiologic factors that influence the equilibrium between energy intake and energy expenditure…”
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Integrating multiplex immunofluorescent and mass spectrometry imaging to map myeloid heterogeneity in its metabolic and cellular context by Goossens, Pieter, Lu, Chang, Cao, Jianhua, Gijbels, Marion J., Karel, Joël M.H., Wijnands, Erwin, Claes, Britt S.R., Fazzi, Gregorio E., Hendriks, Tim F.E., Wouters, Kristiaan, Smirnov, Evgueni, van Zandvoort, Marc J.M., Balluff, Benjamin, Cuypers, Eva, Donners, Marjo M.P.C., Heeren, Ron M.A., Biessen, Erik A.L.

“…Cells often adopt different phenotypes, dictated by tissue-specific or local signals such as cell-cell and cell-matrix contacts or molecular micro-environment…”
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Tumour infiltrating lymphocytes and survival after adjuvant chemotherapy in patients with gastric cancer: post-hoc analysis of the CLASSIC trial by Liu, Drolaiz H. W., Kim, Young-Woo, Sefcovicova, Nina, Laye, Jon P., Hewitt, Lindsay C., Irvine, Andrew F., Vromen, Vincent, Janssen, Yannick, Davarzani, Naser, Fazzi, Gregorio E., Jolani, Shahab, Melotte, Veerle, Magee, Derek R., Kook, Myeong-Cherl, Kim, Hyunki, Langer, Rupert, Cheong, Jae-Ho, Grabsch, Heike I.

“…Background Only a subset of gastric cancer (GC) patients with stage II–III benefits from chemotherapy after surgery. Tumour infiltrating lymphocytes per area…”
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Energy balance‐related factors in childhood and adolescence and risk of colorectal cancer expressing different levels of proteins involved in the Warburg‐effect by Jenniskens, Josien C. A., Offermans, Kelly, Simons, Colinda C. J. M., Samarska, Iryna, Fazzi, Gregorio E., Smits, Kim M., Schouten, Leo J., Weijenberg, Matty P., Grabsch, Heike I., Brandt, Piet A.

“…Early‐life (childhood to adolescence) energy balance‐related factors (height, energy restriction, BMI) have been associated with adult colorectal cancer (CRC)…”
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Energy Balance-Related Factors and Risk of Colorectal Cancer Expressing Different Levels of Proteins Involved in the Warburg Effect by Jenniskens, Josien C A, Offermans, Kelly, Simons, Colinda C J M, Samarska, Iryna, Fazzi, Gregorio E, Smits, Kim M, Schouten, Leo J, Weijenberg, Matty P, Grabsch, Heike I, van den Brandt, Piet A

“…Energy balance-related factors [body mass index (BMI), waist circumference, physical activity] have been associated with colorectal cancer risk. Warburg effect…”
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Validity and Reproducibility of Immunohistochemical Scoring by Trained Non-Pathologists on Tissue Microarrays by Jenniskens, Josien C A, Offermans, Kelly, Samarska, Iryna, Fazzi, Gregorio E, Simons, Colinda C J M, Smits, Kim M, Schouten, Leo J, Weijenberg, Matty P, van den Brandt, Piet A, Grabsch, Heike I

“…Scoring of immunohistochemistry (IHC) staining is often done by non-pathologists, especially in large-scale tissue microarray (TMA)-based studies. Studies on…”
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Pollination of Specklinia by nectar-feeding Drosophila: the first reported case of a deceptive syndrome employing aggregation pheromones in Orchidaceae by Karremans, Adam P., Pupulin, Franco, Grimaldi, David, Beentjes, Kevin K., Butôt, Roland, Fazzi, Gregorio E., Kaspers, Karsten, Kruizinga, Jaco, Roessingh, Peter, Smets, Erik F., Gravendeel, Barbara

“…The first documented observation of pollination in Pleurothallidinae was that of Endrés, who noticed that the 'viscid sepals' of Specklinia endotrachys were…”
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Association between adjuvant therapy and survival in colorectal cancer patients according to metabolic Warburg-subtypes by Offermans, Kelly, Jenniskens, Josien C. A., Simons, Colinda C. J. M., Samarska, Iryna, Fazzi, Gregorio E., Smits, Kim M., Schouten, Leo J., Weijenberg, Matty P., Grabsch, Heike I., van den Brandt, Piet A.

“…Purpose Tumor location and tumor node metastasis (TNM) stage guide treatment decisions in colorectal cancer (CRC) patients. However, patients with the same…”
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Relationship between the Warburg effect in tumour cells and the tumour microenvironment in colorectal cancer patients: Results from a large multicentre study by Steeghs, Jorn P.J.M., Offermans, Kelly, Jenniskens, Josien C.A., Samarska, Iryna, Fazzi, Gregorio E., van den Brandt, Piet A., Grabsch, Heike I.

“…Colorectal cancer (CRC) remains one of the most prevalent and deadly cancers worldwide. The tumour-node-metastasis stage (TNM) is currently the most clinically…”
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Energy balance-related factors and risk of colorectal cancer based on KRAS, PIK3CA, and BRAF mutations and MMR status by Jenniskens, Josien C. A., Offermans, Kelly, Simons, Colinda C. J. M., Samarska, Iryna, Fazzi, Gregorio E., van der Meer, Jaleesa R. M., Smits, Kim M., Schouten, Leo J., Weijenberg, Matty P., Grabsch, Heike I., van den Brandt, Piet A.

“…Introduction KRAS mutations ( KRAS mut ), PIK3CA mut , BRAF mut , and mismatch repair deficiency (dMMR) have been associated with the Warburg-effect. We…”
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Energy balance‐related factors in childhood and adolescence and risk of colorectal cancer based on KRAS, PIK3CA, and BRAF mutations and MMR status by Jenniskens, Josien C. A., Offermans, Kelly, Simons, Colinda C. J. M., Samarska, Iryna, Fazzi, Gregorio E., Meer, Jaleesa R. M., Smits, Kim M., Schouten, Leo J., Weijenberg, Matty P., Grabsch, Heike I., van den Brandt, Piet A.

“…KRAS mutations (KRASmut), PIK3CAmut, BRAFmut, and deficient DNA mismatch repair (dMMR) have been associated with the Warburg effect. We previously reported…”
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Integrative multiomics analysis of human atherosclerosis reveals a serum response factor‐driven network associated with intraplaque hemorrhage by Jin, Han, Goossens, Pieter, Juhasz, Peter, Eijgelaar, Wouter, Manca, Marco, Karel, Joël M. H., Smirnov, Evgueni, Sikkink, Cornelis J. J. M., Mees, Barend M. E., Waring, Olivia, van Kuijk, Kim, Fazzi, Gregorio E., Gijbels, Marion J. J., Kutmon, Martina, Evelo, Chris T. A., Hedin, Ulf, Daemen, Mat J. A. P., Sluimer, Judith C., Matic, Ljubica, Biessen, Erik A. L.

“…Background While single‐omics analyses on human atherosclerotic plaque have been very useful to map stage‐ or disease‐related differences in expression, they…”
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Role of the Rhoa/Rho kinase system in flow-related remodeling of rat mesenteric small arteries in vivo by Wesselman, Jos P M, Kuijs, Robin, Hermans, J J Rob, Janssen, Ger M J, Fazzi, Gregorio E, van Essen, Helma, Evelo, Chris T A, Struijker-Boudier, Harry A J, De Mey, Jo G R

“…In small arteries, a chronic blood flow reduction leads to inward hypotrophic remodeling, while a chronic blood flow elevation induces outward hypertrophic…”
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Impaired Autonomic Regulation of Resistance Arteries in Mice With Low Vascular Endothelial Growth Factor or Upon Vascular Endothelial Growth Factor Trap Delivery by STORKEBAUM, Erik, RUIZ DE ALMODOVAR, Carmen, JANSSEN, Ger M. J, FAZZI, Gregorio E, VERSTREKEN, Patrik, HAIGH, Jody, SCHIFFERS, Paul M, ROHRER, Hermann, VAN DER LINDEN, Annemie, DE MEY, Jo G. R, CARMELIET, Peter, MEENS, Merlijn, ZACCHIGNA, Serena, MAZZONE, Massimiliano, VANHOUTTE, Greet, VINCKIER, Stefan, MISKIEWICZ, Katarzyna, POESEN, Koen, LAMBRECHTS, Diether

“…Control of peripheral resistance arteries by autonomic nerves is essential for the regulation of blood flow. The signals responsible for the maintenance of…”
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