Search Results - "Fazzari, Pietro"

Nrg1 haploinsufficiency alters inhibitory cortical circuits by Navarro-Gonzalez, Carmen, Carceller, Héctor, Benito Vicente, Marina, Serra, Irene, Navarrete, Marta, Domínguez-Canterla, Yaiza, Rodríguez-Prieto, Ángela, González-Manteiga, Ana, Fazzari, Pietro

“…Neuregulin 1 (NRG1) and its receptor ERBB4 are schizophrenia (SZ) risk genes that control the development of both excitatory and inhibitory cortical circuits…”
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A Novel In Vivo Model for Multiplexed Analysis of Callosal Connections upon Cortical Damage by González-Manteiga, Ana, Navarro-González, Carmen, Sebestyén, Valentina Evita, Saborit-Torres, Jose Manuel, Talhada, Daniela, Vayá, María de la Iglesia, Ruscher, Karsten, Fazzari, Pietro

“…Brain damage is the major cause of permanent disability and it is particularly relevant in the elderly. While most studies focused on the immediate phase of…”
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Semaphorin signals in cell adhesion and cell migration: functional role and molecular mechanisms by Casazza, Andrea, Fazzari, Pietro, Tamagnone, Luca

“…Cell migration is pivotal in embryo development and in the adult. During development a wide range of progenitor cells travel over long distances before…”
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Aging Increases Hippocampal DUSP2 by a Membrane Cholesterol Loss-Mediated RTK/p38MAPK Activation Mechanism by Martín-Segura, Adrián, Casadomé-Perales, Álvaro, Fazzari, Pietro, Mas, José Manuel, Artigas, Laura, Valls, Raquel, Nebreda, Angel R, Dotti, Carlos G

“…Numerous studies suggest that the increased activity of p38MAPK plays an important role in the abnormal immune and inflammatory response observed in the course…”
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Transcription factors make a turn into migration by Fazzari, Pietro

“…The formation of the brain depends on a tightly regulated process of proliferation, neuronal fate specification and migration which eventually leads to the…”
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FAK: Dynamic integration of guidance signals at the growth cone by Chacón, Mariola R., Fazzari, Pietro

“…During the formation of neural circuitry, axons are known to be guided to their specific targets by a relatively small arsenal of guidance signals. However,…”
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Plexin-B3 is a functional receptor for semaphorin 5A by Artigiani, Stefania, Conrotto, Paolo, Fazzari, Pietro, Gilestro, Giorgio F, Barberis, Davide, Giordano, Silvia, Comoglio, Paolo M, Tamagnone, Luca

“…Semaphorins are a large family of molecular cues implicated in neural development and in a variety of functions outside the nervous system. Semaphorin 5A…”
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Cell autonomous regulation of hippocampal circuitry via Aph1b-γ-secretase/neuregulin 1 signalling by Fazzari, Pietro, Snellinx, An, Sabanov, Victor, Ahmed, Tariq, Serneels, Lutgarde, Gartner, Annette, Shariati, S Ali M, Balschun, Detlef, De Strooper, Bart

“…Neuregulin 1 (NRG1) and the γ-secretase subunit APH1B have been previously implicated as genetic risk factors for schizophrenia and schizophrenia relevant…”
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Functional Regulation of Semaphorin Receptors by Proprotein Convertases by Artigiani, Stefania, Barberis, Davide, Fazzari, Pietro, Longati, Paola, Angelini, Paola, van de Loo, Jan-Willem, Comoglio, Paolo M, Tamagnone, Luca

“…PLEXIN genes encode receptors for secreted and membrane-bound semaphorins. It was proposed that the extracellular domain of plexins acts as an inhibitory…”
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Cortical distribution of GABAergic interneurons is determined by migration time and brain size by Fazzari, Pietro, Mortimer, Niall, Yabut, Odessa, Vogt, Daniel, Pla, Ramon

“…Cortical interneurons (CINs) originate in the ganglionic eminences (GEs) and migrate tangentially to the cortex guided by different attractive and repulsive…”
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Control of cortical GABA circuitry development by Nrg1 and ErbB4 signalling by Marín, Oscar, Rico, Beatriz, Lloyd, Kent, Valiente, Manuel, Lerma, Juan, Fazzari, Pietro, Pla, Ramón, Luján, Rafael, Paternain, Ana V

“…Schizophrenia is a complex disorder that interferes with the function of several brain systems required for cognition and normal social behaviour. Although the…”
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PLD3 gene and processing of APP by Fazzari, Pietro, Horre, Katrien, Arranz, Amaia M., Frigerio, Carlo Sala, Saito, Takashi, Saido, Takaomi C., De Strooper, Bart

“…We tested the relevance of PLD3 for APP processing in vivo in physiological conditions and in a relevant Alzheimer's disease mouse model and found that PLD3…”
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Protein misfolding and clearance in the pathogenesis of a new infantile onset ataxia caused by mutations in PRDX3 by Martínez-Rubio, Dolores, Rodríguez-Prieto, Ángela, Sancho, Paula, Navarro-González, Carmen, Gorría-Redondo, Nerea, Miquel-Leal, Javier, Marco-Marín, Clara, Jenkins, Alison, Soriano-Navarro, Mario, Hernández, Alberto, Pérez-Dueñas, Belén, Fazzari, Pietro, Aguilera-Albesa, Sergio, Espinós, Carmen

“…Peroxiredoxin 3 (PRDX3) encodes a mitochondrial antioxidant protein, which is essential for the control of reactive oxygen species homeostasis. So far, PRDX3…”
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Nrgl Intracellular Signaling Is Neuroprotective upon Stroke by Navarro-Gonzalez, Carmen, Huerga-Gomez, Alba, Fazzari, Pietro

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Nrg1 Intracellular Signaling Is Neuroprotective upon Stroke by Navarro-González, Carmen, Fazzari, Pietro, Huerga-Gómez, Alba

“…The schizophrenia risk gene NRG1 controls the formation of excitatory and inhibitory synapses in cortical circuits. While the expression of different NRG1…”
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Nrg1 intracellular signaling regulates the development of interhemispheric callosal axons in mice by Rodríguez-Prieto, Ángela, Mateos-White, Isabel, Aníbal-Martínez, Mar, Navarro-González, Carmen, Gil-Sanz, Cristina, Domínguez-Canterla, Yaiza, González-Manteiga, Ana, Del Buey Furió, Verónica, López-Bendito, Guillermina, Fazzari, Pietro

“…Schizophrenia is associated with altered cortical circuitry. Although the schizophrenia risk gene is known to affect the wiring of inhibitory interneurons, its…”
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Nrg1 reverse signaling in cortical pyramidal neurons by Pedrique, Sandra Peregrin, Fazzari, Pietro

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The semaphorin 4D-plexin-B signalLing complex regulates dendritic and axonal complexity in developing neurons via diverse pathways by Vodrazka, Peter, Korostylev, Alexander, Hirschberg, Alexandra, Swiercz, Jakub M., Worzfeld, Thomas, Deng, Suhua, Fazzari, Pietro, Tamagnone, Luca, Offermanns, Stefan, Kuner, Rohini

“…Semaphorins and their receptors, plexins, have emerged as key regulators of various aspects of neuronal development. In contrast to the Plexin‐A family, the…”
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Overexpression of GAP-43 modifies the distribution of the receptors for myelin-associated growth-inhibitory proteins in injured Purkinje axons by Foscarin, Simona, Gianola, Sara, Carulli, Daniela, Fazzari, Pietro, Mi, Sha, Tamagnone, Luca, Rossi, Ferdinando

“…Neurons with enhanced intrinsic growth capabilities can elongate their axons into non‐permissive territories, but the mechanisms that enable the outgrowing…”
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Sema4C-Plexin B2 signalling modulates ureteric branching in developing kidney by Perälä, Nina, Jakobson, Madis, Ola, Roxana, Fazzari, Pietro, Penachioni, Junia Y., Nymark, Mariann, Tanninen, Tiina, Immonen, Tiina, Tamagnone, Luca, Sariola, Hannu

“…Semaphorins, originally identified as axon guidance molecules, have also been implicated in angiogenesis, function of the immune system and cancerous growth…”
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