Search Results - "Fazekas de St Groth, Barbara"
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Immunoprofiling reveals cell subsets associated with the trajectory of cytomegalovirus reactivation post stem cell transplantation
Published in Nature communications (11-05-2022)“…Human cytomegalovirus reactivation is a major opportunistic infection after allogeneic haematopoietic stem cell transplantation and has a complex relationship…”
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2
Stable and Highly Efficient Antibody–Nanoparticles Conjugation
Published in Bioconjugate chemistry (16-06-2021)“…Functional ligands and polymers have frequently been used to yield target-specific bio-nanoconjugates. Herein, we provide a systematic insight into the effect…”
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3
Langerhans cells are precommitted to immune tolerance induction
Published in Proceedings of the National Academy of Sciences - PNAS (01-11-2011)“…Antigen-dependent interactions between T lymphocytes and dendritic cells (DCs) can produce two distinct outcomes: tolerance and immunity. It is generally…”
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4
Selective Treg reconstitution during lymphopenia normalizes DC costimulation and prevents graft-versus-host disease
Published in The Journal of clinical investigation (01-09-2015)“…Regulatory T cells (Tregs) have been shown to enhance immune reconstitution and prevent graft-versus-host disease (GVHD) after hematopoietic stem cell…”
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5
Condensation of the plasma membrane at the site of T lymphocyte activation
Published in The Journal of cell biology (10-10-2005)“…After activation, T lymphocytes restructure their cell surface to form membrane domains at T cell receptor (TCR)-signaling foci and immunological synapses…”
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6
Mass Cytometry Discovers Two Discrete Subsets of CD39 - Treg Which Discriminate MGUS From Multiple Myeloma
Published in Frontiers in immunology (02-08-2019)“…Multiple Myeloma (MM) is preceded by the clinically stable condition monoclonal gammopathy of undetermined significance (MGUS). Critical immune events that…”
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7
Cutaneous immunosurveillance and regulation of inflammation by group 2 innate lymphoid cells
Published in Nature immunology (01-06-2013)“…Innate lymphoid cells (ILCs) have been found in gut and lungs. Weninger and colleagues identify IL-13-producing ILCs in the skin, where they interact with mast…”
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8
Anti-PD-1-induced high-grade hepatitis associated with corticosteroid-resistant T cells: a case report
Published in Cancer Immunology, Immunotherapy (01-04-2018)“…Effective treatment or prevention of immune side effects associated with checkpoint inhibitor therapy of cancer is an important goal in this new era of…”
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9
Effects of storage time and temperature on highly multiparametric flow analysis of peripheral blood samples; implications for clinical trial samples
Published in Bioscience reports (26-02-2021)“…We sought to determine the effect of time and temperature of blood sample storage before preparation of human peripheral blood mononuclear cells (PBMCs) by…”
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10
Infection of CD127+ (Interleukin-7 Receptor+) CD4+ Cells and Overexpression of CTLA-4 Are Linked to Loss of Antigen-Specific CD4 T Cells during Primary Human Immunodeficiency Virus Type 1 Infection
Published in Journal of Virology (01-10-2006)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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11
Accelerated age-dependent transition of human regulatory T cells to effector memory phenotype
Published in International immunology (01-03-2008)“…We and others recently described a method for isolating viable forkhead boxp3 (FoxP3+) T regulatory cells (Tregs) by means of the surface phenotype…”
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12
Pembrolizumab for anaplastic thyroid cancer: a case study
Published in Cancer Immunology, Immunotherapy (01-12-2019)“…Blockade of the PD-1/PD-L1 pathway with targeted monoclonal antibodies has demonstrated encouraging anti-tumour activity in multiple cancer types. We present…”
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13
IL-2 is a critical regulator of group 2 innate lymphoid cell function during pulmonary inflammation
Published in Journal of allergy and clinical immunology (01-12-2015)“…Background Group 2 innate lymphoid cells (ILC2) have been implicated in the pathogenesis of allergic lung diseases. However, the upstream signals that regulate…”
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14
Metabolite-based dietary supplementation in human type 1 diabetes is associated with microbiota and immune modulation
Published in Microbiome (19-01-2022)“…Short-chain fatty acids (SCFAs) produced by the gut microbiota have beneficial anti-inflammatory and gut homeostasis effects and prevent type 1 diabetes (T1D)…”
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15
Cellular and genetic mechanisms of self tolerance and autoimmunity
Published in Nature (02-06-2005)“…The mammalian immune system has an extraordinary potential for making receptors that sense and neutralize any chemical entity entering the body. Inevitably,…”
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16
Mass Cytometry for the Assessment of Immune Reconstitution After Hematopoietic Stem Cell Transplantation
Published in Frontiers in immunology (26-07-2018)“…Mass cytometry, or Cytometry by Time-Of-Flight, is a powerful new platform for high-dimensional single-cell analysis of the immune system. It enables the…”
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17
MHCII restriction demonstrates B cells have very limited capacity to activate tumour-specific CD4 + T cells in vivo
Published in Oncoimmunology (31-12-2024)“…There has been growing interest in the role of B cells in antitumour immunity and potential use in adoptive cellular therapies. To date, the success of such…”
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18
Titration of Mass Cytometry Reagents
Published in Methods in molecular biology (Clifton, N.J.) (2019)“…Mass cytometry (MC) is a powerful research tool enabling high-dimensional analysis of single cells in suspension and within tissue sections following laser…”
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19
High-Dimensional Mass Cytometric Analysis Reveals an Increase in Effector Regulatory T Cells as a Distinguishing Feature of Colorectal Tumors
Published in The Journal of immunology (1950) (15-03-2019)“…T cell infiltration of tumors plays an important role in determining colorectal cancer disease progression and has been incorporated into the Immunoscore…”
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20
Faecal microbial transfer and complex carbohydrates mediate protection against COPD
Published in Gut (08-02-2024)“…Chronic obstructive pulmonary disease (COPD) is a major cause of global illness and death, most commonly caused by cigarette smoke. The mechanisms of…”
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