Search Results - "Fayez, Ahmed M"

A Brain-Targeted Approach to Ameliorate Memory Disorders in a Sporadic Alzheimer's Disease Mouse Model via Intranasal Luteolin-Loaded Nanobilosomes by Elsheikh, Manal A, El-Feky, Yasmin A, Al-Sawahli, Majid Mohammad, Ali, Merhan E, Fayez, Ahmed M, Abbas, Haidy

“…Impaired memory and cognitive function are the main features of Alzheimer's disease (AD). Unfortunately, currently available treatments cannot cure or delay AD…”
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Microporation-Mediated Transdermal Delivery of In Situ Gel Incorporating Etodolac-Loaded PLGA Nanoparticles for Management of Rheumatoid Arthritis by El Sorogy, Heba M, Fayez, Sahar M, Khalil, Islam A, Abdel Jaleel, Gehad A, Fayez, Ahmed M, Eliwa, Hesham A, Teba, Hoda E

“…Management of rheumatoid arthritis (RA) requires long-term administration of different medications since there has been no cure until now. Etodolac (ETD) is a…”
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Novel Luteolin-Loaded Chitosan Decorated Nanoparticles for Brain-Targeting Delivery in a Sporadic Alzheimer's Disease Mouse Model: Focus on Antioxidant, Anti-Inflammatory, and Amyloidogenic Pathways by Abbas, Haidy, Sayed, Nesrine S El, Youssef, Nancy Abdel Hamid Abou, M E Gaafar, Passent, Mousa, Mohamed R, Fayez, Ahmed M, Elsheikh, Manal A

“…Preparation and evaluation of a non-invasive intranasal luteolin delivery for the management of cognitive dysfunction in Alzheimer's disease (AD) using novel…”
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Aspirin-Based Organoiron Dendrimers as Promising Anti-Inflammatory, Anticancer, and Antimicrobial Drugs by Abd-El-Aziz, Alaa S, Benaaisha, Maysun R, Abdelghani, Amani A, Bissessur, Rabin, Abdel-Rahman, Laila H, Fayez, Ahmed M, El-Ezz, Doaa Abou

“…Designing nanocarriers with actions directed at a specific organ or tissue is a very promising strategy since it can significantly reduce the toxicity of a…”
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Hepatoprotective effect of Moringa oleifera extract on TNF-α and TGF-β expression in acetaminophen-induced liver fibrosis in rats by Aly, Omnia, Abouelfadl, Dalia M, Shaker, Olfat G, Hegazy, Gehan A, Fayez, Ahmed M, Zaki, Hanan Hassan

“…BackgroundIt has been reported that Moringa oleifera (MO) has different medicinal properties. The aim of this study was to evaluate the hepatoprotective role…”
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Alpha lipoic acid exerts antioxidant effect via Nrf2/HO-1 pathway activation and suppresses hepatic stellate cells activation induced by methotrexate in rats by Fayez, Ahmed M., Zakaria, Soad, Moustafa, Dina

“…[Display omitted] •Alpha lipoic acid protected from methotrexate-induced hepatic injury.•Alpha lipoic acid suppressed oxidative stress and inflammatory…”
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Non-invasive management of rheumatoid arthritis using hollow microneedles as a tool for transdermal delivery of teriflunomide loaded solid lipid nanoparticles by Abd-El-Azim, Heba, Abbas, Haidy, El Sayed, Nesrine S., Fayez, Ahmed M., Zewail, Mariam

“…[Display omitted] Conventional RA treatments required prolonged therapy courses that have been accompanied with numerous side effects impairing the patient’s…”
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Coconut oil based self-nano emulsifying delivery systems mitigate ulcerogenic NSAIDs side effect and enhance drug dissolution: Formula optimization, in-vitro, and in-vivo assessments by Fayez, Sahar M., Elnahas, Osama S., Fayez, Ahmed M., El-Mancy, Shereen S.

“…[Display omitted] •High percentage of the world population is subjected to gastric ulcer disease due to the excess use of NSAIDs.•Diclofenac potassium (as a…”
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Characterization and Pharmacological Evaluation of Anti-Cellulite Herbal Product(s) Encapsulated in 3D-Fabricated Polymeric Microneedles by Amer, Reham I., El-Osaily, Ghada H., Bakr, Riham O., El Dine, Riham Salah, Fayez, Ahmed M.

“…Skin health is vital for a healthy body. Herbal remedies have long been used for skin care, and their global use has tremendously increased over the past three…”
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Amelioration of autoimmunity and inflammation by zinc oxide nanoparticles in experimental rheumatoid arthritis by Gad, Sameh S., Fayez, Ahmed M., Abdelaziz, Mahmoud, Abou El-ezz, Doaa

“…Rheumatoid arthritis (RA) is a chronic autoimmune disease that affects the lining of the synovial joints and approximately affects 0.5 − 1% of the total…”
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Thioacetamide-induced acute hepatic encephalopathy: central vs peripheral effect of Allicin by Saleh, Dalia O., Mansour, Dina F., Fayez, Ahmed M.

“…Hepatic encephalopathy (HE) is a debilitating and life-threatening disease. Results from acute or chronic liver failure and is characterized by abnormal…”
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Evaluation of the hepatoprotective activity of Pulicaria incisa subspecies candolleana and in silico screening of its isolated phenolics by Bakr, Riham O., Shahat, Esraa A., Elissawy, Ahmed E., Fayez, Ahmed M., Eldahshan, Omayma A.

“…Pulicaria incisa sub. candolleana E. Gamal-Eldin (Asteraceae) was traditionally used by Bedouins as a refreshing tea and as hypoglycemic, in gastrointestinal…”
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Neuroprotective effects of Sophora secundiflora , Sophora tomentosa leaves and formononetin on scopolamine-induced dementia by Aly, Shaza H, Elissawy, Ahmed M, Fayez, Ahmed M, Eldahshan, Omayma A, Elshanawany, Mohamed A, Singab, Abdel Nasser B

“…Five flavonoids were isolated from the ethyl acetate fraction of leaves of ; formononetin , 5-hydroxy-4'-methoxyflavone , genistein ,…”
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Neuroprotective effects of zafirlukast, piracetam and their combination on L‐Methionine‐induced vascular dementia in rats by Fayez, Ahmed M., Elnoby, Ahmed S., Bahnasawy, Nada H., Hassan, Omar

“…Vascular dementia is considered a vascular cognitive impairment disease caused by neuronal degeneration in the brain. Several studies have supported the…”
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Morin post-treatment surpassed calpeptin in ameliorating 3-NP-induced cortical neurotoxicity via modulation of glutamate/calpain axis, Kidins220, and BDNF/TrkB/AKT/CREB trajectory by Mohamed, Ola E., Abdallah, Dalaal M., Fayez, Ahmed M., Mohamed, Reem A., El-Abhar, Hanan S.

“…MH and/or CP mitigate HD via deactivating glutamate/calpain, KIDINS220, neuro-inflammation, and oxidative stress, while activating the BDNF/TrkB/AKT/CREB…”
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Pharmaceutical and Pharmacological Evaluation of the Effect of Nano-Formulated Spironolactone and Progesterone on Inflammation and Hormonal Levels for Managing Hirsutism Experimentally Induced in Rats by Amer, Reham I., Yassin, Ghada E., Mohamed, Reem A., Fayez, Ahmed M.

“…Hirsutism is a dermatological condition that refers to the excessive growth of hair in androgen-sensitive areas in women. Recently, the enhancement of the…”
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Uro-protective role of chrysin against cyclophosphamide-induced hemorrhagic cystitis in rats involving the turning-off NF-κB/P38-MAPK, NO/PARP-1 and STAT-3 signaling cascades by Saleh, Dalia O., El-Nasr, Nesma M.E. Abo, Fayez, Ahmed M., Ahmed, Kawkab A., Mohamed, Reem A.

“…Chemotherapeutic agents are used to treat a wide range of cancer types, but they cause serious side effects which must be managed after treatment…”
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Comparative lyophilized platelet-rich plasma wafer and powder for wound-healing enhancement: formulation, in vitro and in vivo studies by Yassin, Ghada E., Dawoud, Marwa H. S., Wasfi, Reham, Maher, Ahmed, Fayez, Ahmed M.

“…Platelet-rich plasma (PRP) accelerates wound healing, as it is an excellent source of growth factors. PRP was separated from whole human blood by…”
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Novel tetrazole-based selective COX-2 inhibitors: Design, synthesis, anti-inflammatory activity, evaluation of PGE2, TNF-α, IL-6 and histopathological study by Labib, Madlen B., Fayez, Ahmed M., EL-Nahass, EL-Shaymaa, Awadallah, M., Halim, Peter A.

“…[Display omitted] •Novel tetrazole derivatives were designed and synthesized.•Bioisosteric replacement of SO2NH2 in celecoxib with tetrazole ring was…”
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Eicosapentaenoic Acid and Vitamin E Against Doxorubicin Induced Cardiac and Renal Damages: Role of Cytochrome c and iNOS by Fayez, Ahmed M, Zaafan, Mai A

“…Background: The current study aimed to evaluate the mechanisms involved in protection against doxorubicin-induced cardiac and renal toxicities upon treatment…”
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