Search Results - "Fayed, Eman A"

Quinoline derivatives bearing pyrazole moiety: Synthesis and biological evaluation as possible antibacterial and antifungal agents by El Shehry, Mohamed F., Ghorab, Mostafa M., Abbas, Samir Y., Fayed, Eman A., Shedid, Said A., Ammar, Yousry A.

“…In an attempt for development of new antimicrobial agents, three series of quinoline derivatives bearing pyrazole moiety have been synthesized. The first…”
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One-Pot Synthesis and Molecular Modeling Studies of New Bioactive Spiro-Oxindoles Based on Uracil Derivatives as SARS-CoV-2 Inhibitors Targeting RNA Polymerase and Spike Glycoprotein by El-Kalyoubi, Samar A, Ragab, Ahmed, Abu Ali, Ola A, Ammar, Yousry A, Seadawy, Mohamed G, Ahmed, Aya, Fayed, Eman A

“…The first outbreak in Wuhan, China, in December 2019 was reported about severe acute coronaviral syndrome 2 (SARS-CoV-2). The global coronavirus disease 2019…”
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Fluorinated indeno-quinoxaline bearing thiazole moieties as hypoglycaemic agents targeting α -amylase, and α -glucosidase: synthesis, molecular docking, and ADMET studies by Gohar, Nirvana A, Fayed, Eman A, A Ammar, Yousry, A Abu Ali, Ola, Ragab, Ahmed, Mahfoz, Amal M, Abusaif, Moustafa S

“…Inhibition of α-glucosidase and -amylase are key tactics for managing blood glucose levels. Currently, stronger, and more accessible inhibitors are needed to…”
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Erratum to “Facile synthesis and in vitro anticancer evaluation of a new series of tetrahydroquinoline” [Heliyon 7(10) (October 2021) e08117] by Fathy, Usama, Abd El Salam, Hayam A., Fayed, Eman A., Elgamal, Abdelbaset M., Gouda, Ahmed

“…[This corrects the article DOI: 10.1016/j.heliyon.2021.e08117.]…”
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One pot synthesis, antimicrobial and antioxidant activities of fused uracils: pyrimidodiazepines, lumazines, triazolouracil and xanthines by El-Kalyoubi, Samar A., Fayed, Eman A., Abdel-Razek, Ahmed S.

“…Background Uracil derivatives have a great attraction because they play an important role in pharmacological activities. Pyrimidodiazepines, lumazines,…”
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Interception of Epoxide ring to quorum sensing system in Enterococcus faecalis and Staphylococcus aureus by Refai, Mohammed Y., Elazzazy, Ahmed M., Desouky, Said E., Abu-Elghait, Mohammed, Fayed, Eman A., Alajel, Sulaiman M., Alajlan, Abdullah A., Albureikan, Mona O., Nakayama, Jiro

“…Quorum sensing inhibitor (QSI) has been attracting attention as anti-virulence agent which disarms pathogens of their virulence rather than killing them. QSI…”
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Secondary Metabolites of Actinomycetales as Potent Quorum Sensing Inhibitors Targeting Gram-Positive Pathogens: In Vitro and In Silico Study by Desouky, Said E, Abu-Elghait, Mohammed, Fayed, Eman A, Selim, Samy, Yousuf, Basit, Igarashi, Yasuhiro, Abdel-Wahab, Basel A, Mohammed Alsuhaibani, Amnah, Sonomoto, Kenji, Nakayama, Jiro

“…Anti-virulence agents are non-bacteriostatic and non-bactericidal emerging therapeutic options which hamper the production of virulence factors in pathogenic…”
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Facile synthesis and in vitro anticancer evaluation of a new series of tetrahydroquinoline by Fathy, Usama, Abd El Salam, Hayam A., Fayed, Eman A., Elgamal, Abdelbaset M., Gouda, Ahmed

“…Tetrahydroquinoline (THQ) is an important structure for synthesizing multiple biologically active derivatives. Thus, we developed new quinoline derivatives and…”
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Erratum to: One pot synthesis, antimicrobial and antioxidant activities of fused uracils: pyrimidodiazepines, lumazines, triazolouracil and xanthines by El-Kalyoubi, Samar A., Fayed, Eman A., Abdel-Razek, Ahmed S.

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Apoptosis induction, PARP-1 inhibition, and cell cycle analysis of leukemia cancer cells treated with novel synthetic 1,2,3-triazole-chalcone conjugates by Othman, Esraa M., Fayed, Eman A., Husseiny, Ebtehal M., Abulkhair, Hamada S.

“…[Display omitted] •A novel series of 1,2,3-triazoles bearing chalcone fragments was designed, synthesized.•The cytotoxic activity of the synthesized compounds…”
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Hydrazonoyl bromide precursors as DHFR inhibitors for the synthesis of bis-thiazolyl pyrazole derivatives; antimicrobial activities, antibiofilm, and drug combination studies against MRSA by Ibrahim, Seham A., Fayed, Eman A., Rizk, Hala F., Desouky, Said E., Ragab, Ahmed

“…[Display omitted] •A series of new bis-thiazolyl pyrazole derivatives 3-6 were synthetized.•Antimicrobial screening activity and MIC and SAR study were…”
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Novel structural hybrids of quinoline and thiazole moieties: Synthesis and evaluation of antibacterial and antifungal activities with molecular modeling studies by Eissa, Sally I., Farrag, Amel M., Abbas, Samir Y., El Shehry, Mohamed F., Ragab, Ahmed, Fayed, Eman A., Ammar, Yousry A.

“…Various new three series of quinoline derivatives bearing thiazole moiety have been synthesized and evaluated for antibacterial and antifungal activities…”
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The effect of novel synthetic semicarbazone- and thiosemicarbazone-linked 1,2,3-triazoles on the apoptotic markers, VEGFR-2, and cell cycle of myeloid leukemia by Othman, Esraa M., Fayed, Eman A., Husseiny, Ebtehal M., Abulkhair, Hamada S.

“…[Display omitted] •Twelve 1,2,3-triazoles bearing semicarbazone and thiosemicarbazone fragments were designed and synthesized.•Their cytotoxicity was evaluated…”
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Synthetic coumarin derivatives with anticoagulation and antiplatelet aggregation inhibitory effects by Ramsis, Triveena M., Ebrahim, Maha A., Fayed, Eman A.

“…Thrombosis is the leading cause of illness and mortality worldwide, posing a serious risk to human health and life. Because antithrombotic drugs can prevent…”
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The role of current synthetic and possible plant and marine phytochemical compounds in the treatment of acne by Ramsis, Triveena, Refat M Selim, Heba Mohammed, Elseedy, Howida, Fayed, Eman A

“…Acne is a long-standing skin condition characterized by plugged hair follicles due to the accumulation of dead skin cells, sebum, and ( ) bacteria, causing…”
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Development of new spiro[1,3]dithiine-4,11′-indeno[1,2-b]quinoxaline derivatives as S. aureus Sortase A inhibitors and radiosterilization with molecular modeling simulation by Ragab, Ahmed, Abusaif, Moustafa S., Gohar, Nirvana A., Aboul-Magd, Dina S., Fayed, Eman A., Ammar, Yousry A.

“…[Display omitted] •New spiro-1,3-dithiinoindenoquinoxaline derivatives were efficiently synthesized.•The structures of all obtained products were elucidated by…”
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Design, synthesis, biological evaluation and molecular modeling of new coumarin derivatives as potent anticancer agents by Fayed, Eman A., Sabour, Rehab, Harras, Marwa F., Mehany, Ahmed B. M.

“…A novel series of coumarin-pyridine/fused pyridine hybrids were designed and synthesized. Their anticancer activity was evaluated against human cancer cell…”
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In vivo screening and toxicity studies of indolinone incorporated thiosemicarbazone, thiazole and piperidinosulfonyl moieties as anticonvulsant agents by Fayed, Eman A., Ragab, Ahmed, Ezz Eldin, Rogy R., Bayoumi, Ashraf H., Ammar, Yousry A.

“…[Display omitted] •A series of thiazoles and thiosemicarbazones based piperidino-sulfonyl indoline-2,3-dione were designed and synthesized.•Twenty-five of…”
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In vitro cytotoxic activity of thiazole-indenoquinoxaline hybrids as apoptotic agents, design, synthesis, physicochemical and pharmacokinetic studies by Fayed, Eman A., Ammar, Yousry A., Ragab, Ahmed, Gohar, Nirvana A., Mehany, Ahmed B.M., Farrag, Amel M.

“…In silico assessment of all the potent compounds pharmacokinetic, drug-likeness and PAINS alerts profiles was performed. [Display omitted] •Novel 25…”
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In vitro antimicrobial evaluation and in silico studies of coumarin derivatives tagged with pyrano-pyridine and pyrano-pyrimidine moieties as DNA gyrase inhibitors by Fayed, Eman A., Nosseir, Eman S., Atef, Ahmed, El‑Kalyoubi, Samar A.

“…Several coumarin-containing substitute nitrogen heterocycles have recently received considerable importance due to their diverse pharmacological properties…”
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